| Drug Name: | Phenprocoumon (435-97-2) |
|---|---|
| PubChem ID: | 54680692 |
| SMILES: | CCC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O |
| InchiKey: | DQDAYGNAKTZFIW-UHFFFAOYSA-N |
| Therapeutic Category: | Anticoagulants, Hematologic Agents |
| Molecular Weight (dalton) | : | 280.323 |
| LogP | : | 4.0405 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 50.44 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Amiodarone (1951-25-3) | Bleeding | Antagonistic | Amiodarone inhibits the metabolism of Phenprocoumon, probably because it,and/'or its metabolite desethylamiodarone, inhibit the cytochrome P450isoenzyme CYP2C9, CYP3A4 and CYP1A3 | Dangers of amiodarone and anticoagulant treatment |
| Clarithromycin (81103-11-9) | Bleeding | Antagonistic | Not understood | Interaction between clarithromycin and oral anticoagulants |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category