| Drug Name: | Phenindione (83-12-5) |
|---|---|
| PubChem ID: | 4760 |
| SMILES: | C1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O |
| InchiKey: | NFBAXHOPROOJAW-UHFFFAOYSA-N |
| Therapeutic Category: | Anticoagulants, Hematologic Agents |
| Molecular Weight (dalton) | : | 222.243 |
| LogP | : | 2.8494 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 34.14 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Cefixime (79350-37-1) | Anticoagulation | Additive | Cephalosporins with an N-methylthiotetrazole side-chain can, like the oral anticoagulants, act as vitamin K antagonists to reduce the production of some blood clotting factors. They can therefore cause bleeding on their own. | Influence of cephalosporin antibiotics on blood coagulation and platelet function |
| Ethylestrenol (965-90-2) | Bleeding | Antagonistic | Not understood | Suspected interaction between phenindione and ethyloestrenol |
| Oxymetholone (434-07-1) | Bleeding | Antagonistic | Not understood | EFFECTS OF ANABOLIC STEROIDS ON ANTICOAGULANT REQUIREMENTS |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category