InAADR

Drug Information

Drug Name: Perphenazine (58-39-9)
PubChem ID: 4748
SMILES: C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
InchiKey: RGCVKNLCSQQDEP-UHFFFAOYSA-N
Therapeutic Category: Antipsychotic Agents, Central Nervous System Agents, Central Nervous System Depressants, Dopamine Agents, Dopamine Antagonists, Neurotransmitter Agents, Psychotropic Drugs, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 403.979
LogP: 3.9427
Ring Count: 2
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 29.95

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Minocycline (10118-90-8) Galactorrhoea Additive Unknown Black galactorrhea as a consequence of minocycline and phenothiazine therapy

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abnormal Behaviour ADReCS
Abnormal Dreams ADReCS
Abnormal Gait MetaADEDB
Abscess MetaADEDB
Abscess Drainage MetaADEDB
Acetonaemia MetaADEDB
Ache SIDER
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Actinomycosis MetaADEDB
Acute Febrile Neutrophilic Dermatosis MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adverse Drug Effect MetaADEDB
Affective Disorder MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Akathisia ADReCS
Allergy To Metals MetaADEDB
Alopecia MetaADEDB
Alveolar Osteitis MetaADEDB
Alzheimer Disease MetaADEDB
Amenorrhea MetaADEDB
Amenorrhoea ADReCS
Amnesia MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Angioedema ADReCS
Angiopathy MetaADEDB
Anhedonia MetaADEDB
Anorexia ADReCS
Anti-Thyroid Antibody Positive MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Anxiety MetaADEDB
Apathy MetaADEDB
Artificial Crown Procedure MetaADEDB
Asphyxia ADReCS
Aspiration Pleural Cavity MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Asystole MetaADEDB
Ataxia ADReCS
Atrial Tachycardia MetaADEDB
Atrioventricular Block Second Degree MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Back Ache MetaADEDB
Back Injury MetaADEDB
Bad Breath MetaADEDB
Balance Disorder MetaADEDB
Basal Ganglia Diseases MetaADEDB
Benign Tumour Excision MetaADEDB
Beta Haemolytic Streptococcal Infection MetaADEDB
Bile Duct Stone MetaADEDB
Bipolar Disorder MetaADEDB
Bladder Disorder MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Bleeding Hemorrhoids MetaADEDB
Blood Bicarbonate MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Disorder SIDER
Blood Iron Increased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bone Debridement MetaADEDB
Bone Giant Cell Tumour MetaADEDB
Bone Graft MetaADEDB
Bone Marrow Oedema MetaADEDB
Bone Spur MetaADEDB
Bradycardia ADReCS
Brain Oedema ADReCS
Brain Operation MetaADEDB
Breast Enlargement ADReCS
Breast Feeding ADReCS
Breath Sounds Abnormal MetaADEDB
Bronchitis MetaADEDB
Bronchitis MetaADEDB
Bruxism MetaADEDB
Bulbar Palsy MetaADEDB
Bulging MetaADEDB
Calculus Urethral MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Arrest ADReCS
Cardiac Disease MetaADEDB
Cardiac Murmur MetaADEDB
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Cataract MetaADEDB
Catatonia ADReCS
Central Nervous System Stimulation MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebellar Diseases MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Chill MetaADEDB
Choking Sensation MetaADEDB
Cholestasis ADReCS
Chorea MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Circadian Rhythm Sleep Disorder MetaADEDB
Circulatory Collapse ADReCS
Cognitive Disorder MetaADEDB
Colitis Pseudomembranous MetaADEDB
Colon Spastic MetaADEDB
Communication Disorder MetaADEDB
Completed Suicide MetaADEDB
Concomitant Disease Aggravated MetaADEDB
Confusional State ADReCS
Conjunctival Deposit MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Convulsive Seizure SIDER
Cough ADReCS
Csf Protein MetaADEDB
Csf Protein Abnormal ADReCS
Cyst MetaADEDB
Cytolytic Hepatitis ADReCS
Deafness MetaADEDB
Deafness Congenital MetaADEDB
Death ADReCS
Decreased Activity MetaADEDB
Decreased Appetite ADReCS
Decreased Interest MetaADEDB
Decreased Libido MetaADEDB
Deglutition Disorders MetaADEDB
Dehydration MetaADEDB
Delusion MetaADEDB
Delusional Disorder Unspecified Type MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Caries MetaADEDB
Dental Examination MetaADEDB
Dental Operation MetaADEDB
Dental Pain MetaADEDB
Depressive Disorder MetaADEDB
Depressive Disorder Major MetaADEDB
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Dermatitis Contact ADReCS
Dermatitis Exfoliative ADReCS
Device Failure MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Complication MetaADEDB
Diabetic Eye Disease MetaADEDB
Diabetic Gastroparesis MetaADEDB
Diabetic Nephropathy MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Diabetic Ulcer MetaADEDB
Diabetic Vascular Disorder MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Progression MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Retinal MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Interaction MetaADEDB
Drug Tolerance MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Syndrome Neonatal MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dysarthria ADReCS
Dysgeusia MetaADEDB
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyskinesias MetaADEDB
Dyslipidaemia MetaADEDB
Dysphagia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dystonia ADReCS
Easy Bruisability MetaADEDB
Eating Disorder MetaADEDB
Eczema ADReCS
Edema Cerebral SIDER
Edema Extremities MetaADEDB
Effusion MetaADEDB
Ejaculation Disorder ADReCS
Electrocardiogram Abnormal ADReCS
Electrocardiogram Qrs Complex MetaADEDB
Electroencephalogram Abnormal ADReCS
Elevated Triglycerides MetaADEDB
Embolism Pulmonary MetaADEDB
Emphysema MetaADEDB
Endodontic Procedure MetaADEDB
Eosinophilia ADReCS
Eosinophilic Myocarditis MetaADEDB
Epidural Lipomatosis MetaADEDB
Epilepsy MetaADEDB
Epinephrine Abnormal ADReCS
Erythema ADReCS
Erythema Multiforme MetaADEDB
Excess Potassium MetaADEDB
Excitement SIDER
Exercise Tolerance Decreased MetaADEDB
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Extremity Pain MetaADEDB
Eye Disorder ADReCS
Eye Injury MetaADEDB
Eyelid Diseases MetaADEDB
Facial Neuralgia MetaADEDB
Facial Paralysis MetaADEDB
Faecalith ADReCS
Faecaloma ADReCS
Fat Tissue Increased MetaADEDB
Feeling Abnormal ADReCS
Feeling Drunk MetaADEDB
Fever MetaADEDB
Fibroids MetaADEDB
Fibrosis MetaADEDB
Flooding MetaADEDB
Foreign Body In Eye ADReCS
Fungal Disease MetaADEDB
Galactorrhea MetaADEDB
Galactorrhoea ADReCS
Gastric Hyperplasia MetaADEDB
Gastroenteritis MetaADEDB
Gingival Disorder MetaADEDB
Glaucoma ADReCS
Glossodynia ADReCS
Glucose Intolerance MetaADEDB
Glycosuria ADReCS
Granulocytosis MetaADEDB
Gynaecomastia ADReCS
Haematoma MetaADEDB
Haemolytic Anaemia ADReCS
Hallucinations MetaADEDB
Head Injury MetaADEDB
Head Titubation MetaADEDB
Headache ADReCS
Heart Attack MetaADEDB
Heart Rate Abnormal ADReCS
Hematoma Subdural MetaADEDB
Hemiparesis MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatitis A ADReCS
Hepatocellular Injury ADReCS
Hernia Repair MetaADEDB
Hiccup MetaADEDB
High Blood Pressure MetaADEDB
Hyperemesis Gravidarum MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkinesia ADReCS
Hyperlipaemia MetaADEDB
Hyperosmolar State MetaADEDB
Hyperphagia ADReCS
Hyperprolactinemia MetaADEDB
Hyperpyrexia ADReCS
Hyperreflexia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia MetaADEDB
Hypertrichosis MetaADEDB
Hypertrophy ADReCS
Hyperventilation MetaADEDB
Hypoaesthesia ADReCS
Hypoglycaemia ADReCS
Hypogonadism MetaADEDB
Hypoproteinaemia MetaADEDB
Hypotension ADReCS
Hypotensive SIDER
Hypoxia MetaADEDB
Ileus ADReCS
Ileus Paralytic ADReCS
Iliotibial Band Syndrome MetaADEDB
Impaired Healing MetaADEDB
Impingement Syndrome MetaADEDB
Inappropriate Antidiuretic Hormone Secretion ADReCS
Incisional Drainage MetaADEDB
Incontinence ADReCS
Increased Appetite ADReCS
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Injection Site Erythema MetaADEDB
Insomnia ADReCS
Insulin Resistance MetaADEDB
Intermittent Explosive Disorder MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intervertebral Disc Operation MetaADEDB
Intervertebral Disc Space Narrowing MetaADEDB
Ischaemia MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaw Disorder MetaADEDB
Keratopathy ADReCS
Kidney Failure MetaADEDB
Knee Deformity MetaADEDB
Lactose Intolerance MetaADEDB
Laryngeal Oedema ADReCS
Lens Disorder ADReCS
Lenticular Opacities ADReCS
Lethargy ADReCS
Leukopenia ADReCS
Libido Disorder ADReCS
Liver Injury ADReCS
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Lumbar Radiculopathy MetaADEDB
Lung Operation MetaADEDB
Lupus Erythematosus SIDER
Maculopathy ADReCS
Malignant Pleural Effusion MetaADEDB
Malignant Syndrome Nos SIDER
Mastication Disorder ADReCS
Medical Device Removal MetaADEDB
Melanocytic Naevus MetaADEDB
Menstrual Disorder ADReCS
Mental Disorders MetaADEDB
Mental Status Changes MetaADEDB
Mesenteric Occlusion MetaADEDB
Metabolic Acidosis MetaADEDB
Metabolic Disorder MetaADEDB
Metabolic Syndrome MetaADEDB
Metastatic Neoplasm MetaADEDB
Methemoglobinemia MetaADEDB
Miosis ADReCS
Mood Altered MetaADEDB
Motor Restlessness SIDER
Mouth Breathing MetaADEDB
Movement Disorders MetaADEDB
Movements Involuntary SIDER
Mucous Membrane Disorder ADReCS
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort MetaADEDB
Musculoskeletal Pain MetaADEDB
Mydriasis ADReCS
Myelopathy MetaADEDB
Myocarditis MetaADEDB
Myoglobin Blood Increased MetaADEDB
Myoglobinuria MetaADEDB
Myopia MetaADEDB
Nasal Congestion ADReCS
Nasal Septal Perforation MetaADEDB
Nasal Septum Deviation MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Neoplasia MetaADEDB
Neumonia MetaADEDB
Neurectomy MetaADEDB
Neurogenic Bladder ADReCS
Neuroleptic Malignant Syndrome ADReCS
Neuroma MetaADEDB
Neuropathy Peripheral MetaADEDB
Neutrophilia MetaADEDB
Numbness SIDER
Nystagmus MetaADEDB
Obstipation SIDER
Obstruction Gastric MetaADEDB
Ocular Motility Disorders MetaADEDB
Oculogyric Crisis ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Discomfort MetaADEDB
Oophorectomy Bilateral MetaADEDB
Opisthotonus ADReCS
Optic Neuropathy MetaADEDB
Oral Disorder MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Orthostatic Hypotension ADReCS
Osteitis Deformans MetaADEDB
Osteoarthritis ADReCS
Osteomyelitis MetaADEDB
Osteopetrosis MetaADEDB
Osteosclerosis MetaADEDB
Ovarian Cyst MetaADEDB
Pain ADReCS
Pain Pelvic MetaADEDB
Pallor ADReCS
Pancreatic Cyst MetaADEDB
Pancreatitis MetaADEDB
Pancreatitis Chronic MetaADEDB
Pancytopenia ADReCS
Paralysis ADReCS
Paralysis Of Bladder SIDER
Paranoia ADReCS
Parkinson Disease Secondary MetaADEDB
Parkinsonian Disorders MetaADEDB
Parkinsonism ADReCS
Parotid Gland Enlargement ADReCS
Parotid Swelling SIDER
Periodontal Operation MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phlebothrombosis MetaADEDB
Photophobia ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pigmentation SIDER
Pigmentation Disorder ADReCS
Pigmentation Skin SIDER
Platelet Adhesiveness Abnormal MetaADEDB
Pleural Effusion MetaADEDB
Poikilocytosis MetaADEDB
Pollakiuria ADReCS
Polychromasia MetaADEDB
Polymedication MetaADEDB
Polyneuropathy Idiopathic Progressive MetaADEDB
Polyuria ADReCS
Poor Personal Hygiene MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Pregnancy Test False Positive ADReCS
Pregnancy Test Positive ADReCS
Presbyopia MetaADEDB
Protrusion Tongue ADReCS
Pruritus ADReCS
Pseudodementia MetaADEDB
Psychomotor Agitation MetaADEDB
Psychomotor Disorders MetaADEDB
Psychomotor Hyperactivity ADReCS
Psychotic Disorder ADReCS
Psychotic Disorders MetaADEDB
Purpura ADReCS
Purulence MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Pyrexia ADReCS
Pyuria MetaADEDB
Qrs Axis Abnormal MetaADEDB
Radiculotomy MetaADEDB
Rectal Prolapse MetaADEDB
Renal Colic MetaADEDB
Restlessness ADReCS
Retinal Disorder ADReCS
Retinal Pigmentation ADReCS
Retinitis Pigmentosa ADReCS
Retrocollis MetaADEDB
Rhabdomyolysis MetaADEDB
Risus Sardonicus MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Schizophrenia MetaADEDB
Schizophrenia Paranoid MetaADEDB
Schizophrenia Paranoid Type MetaADEDB
Seizures SIDER
Sensitivity Of Teeth MetaADEDB
Sensorimotor Disorder MetaADEDB
Sensory Loss ADReCS
Septic Necrosis MetaADEDB
Serum Ferritin Decreased MetaADEDB
Shock ADReCS
Sinus Disorder MetaADEDB
Sinus Operation MetaADEDB
Sinus Polyp MetaADEDB
Skin Discolouration ADReCS
Skin Erosion MetaADEDB
Skin Pigmentation ADReCS
Sleep Initiation And Maintenance Disorders MetaADEDB
Slurred Speech SIDER
Soft Tissue Disorder MetaADEDB
Somnambulism MetaADEDB
Somnolence ADReCS
Spasm MetaADEDB
Speech Disorders MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Osteoarthritis MetaADEDB
Splenic Infarction MetaADEDB
Spondylolisthesis MetaADEDB
Sputum Discoloured MetaADEDB
Staphylococcal Infection MetaADEDB
Subcutaneous Abscess MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sudden Death ADReCS
Suicidal Behaviour MetaADEDB
Sweating SIDER
Swelling ADReCS
Syncope ADReCS
Systemic Lupus Erythematosus ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tardive Dyskinesia ADReCS
Tearfulness MetaADEDB
Temperature Regulation Disorder MetaADEDB
Tenderness ADReCS
Tendinitis MetaADEDB
Tendon Disorder MetaADEDB
Tendon Rupture MetaADEDB
Thoracotomy MetaADEDB
Throat Sore SIDER
Throat Tightness ADReCS
Thrombocytopenic Purpura ADReCS
Thrombophlebitis MetaADEDB
Thyroid Disease MetaADEDB
Tic Disorders MetaADEDB
Tinnitus MetaADEDB
Tobacco Abuse MetaADEDB
Toe Amputation MetaADEDB
Tongue Discolouration ADReCS
Tongue Paralysis MetaADEDB
Tooth Development Disorder MetaADEDB
Tooth Discolouration MetaADEDB
Tooth Extraction MetaADEDB
Tooth Impacted ADReCS
Tooth Repair MetaADEDB
Torticollis ADReCS
Tremor MetaADEDB
Trismus ADReCS
Troponin I Increased MetaADEDB
Urethral Stenosis MetaADEDB
Urinary Retention ADReCS
Urine Output Increased ADReCS
Urticaria ADReCS
Vascular Operation MetaADEDB
Vascular Purpura ADReCS
Vena Cava Filter Insertion MetaADEDB
Ventricular Fibrillation MetaADEDB
Vision Blurred ADReCS
Vision Disorders MetaADEDB
Vitamin B 12 Deficiency MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis MetaADEDB
Weakness SIDER
Weight Fluctuation MetaADEDB
Weight Gain MetaADEDB
Wheelchair User MetaADEDB
Wheeze MetaADEDB

InAADR: Drug-Protein-ADRs database