InAADR

Drug Information

Drug Name: Paliperidone (144598-75-4)
PubChem ID: 115237
SMILES: CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
InchiKey: PMXMIIMHBWHSKN-UHFFFAOYSA-N
Therapeutic Category: Antipsychotic Agents, Central Nervous System Agents, Central Nervous System Depressants, Psychotropic Drugs, Tranquilizing Agents

Computed Drug Properties

Molecular Weight (dalton): 426.492
LogP: 3.08132
Ring Count: 3
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 84.39

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abnormal Involuntary Movements ADReCS
Acarodermatitis PROTECT
Acne PROTECT
Aggression ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Akathisia ADReCS
Akinesia PROTECT
Alanine Aminotransferase Increased SIDER
Alopecia PROTECT
Amenorrhoea ADReCS
Anaemia PROTECT
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anorgasmia PROTECT
Antiemetic Supportive Care ADReCS
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Arrhythmia ADReCS
Arthralgia ADReCS
Aspartate Aminotransferase Increased SIDER
Aspiration ADReCS
Asthenia ADReCS
Athetosis PROTECT
Atrial Fibrillation PROTECT
Atrioventricular Block SIDER
Atrioventricular Block First Degree ADReCS
Back Pain ADReCS
Balance Disorder PROTECT
Blepharospasm PROTECT
Blood Cholesterol Abnormal ADReCS
Blood Cholesterol Increased ADReCS
Blood Creatine Phosphokinase Increased ADReCS
Blood Glucose Increased ADReCS
Blood Insulin Abnormal ADReCS
Blood Insulin Increased ADReCS
Blood Pressure Increased ADReCS
Blood Test Abnormal ADReCS
Blood Triglycerides Abnormal ADReCS
Blood Triglycerides Increased ADReCS
Blunted Affect PROTECT
Body Temperature Decreased PROTECT
Body Temperature Increased ADReCS
Bradycardia ADReCS
Bradykinesia ADReCS
Breast Discharge ADReCS
Breast Discomfort ADReCS
Breast Disorder SIDER
Breast Engorgement ADReCS
Breast Enlargement PROTECT
Breast Pain ADReCS
Breast Swelling ADReCS
Breast Tenderness ADReCS
Bronchitis ADReCS
Bundle Branch Block ADReCS
Bundle Branch Block Left ADReCS
Cardiac Arrest PROTECT
Cardiac Disorder ADReCS
Cellulitis PROTECT
Cerebral Ischaemia PROTECT
Cerebrovascular Accident ADReCS
Cerebrovascular Disorder ADReCS
Cheilitis PROTECT
Chest Discomfort PROTECT
Chest Pain PROTECT
Chills PROTECT
Choreoathetosis ADReCS
Cognitive Disorder ADReCS
Cogwheel Rigidity ADReCS
Completed Suicide ADReCS
Conduction Disorder PROTECT
Confusional State ADReCS
Conjunctivitis PROTECT
Connective Tissue Disorder SIDER
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Cough ADReCS
Creatine Phosphokinase Increased SIDER
Cystitis PROTECT
Dandruff PROTECT
Death ADReCS
Decreased Appetite ADReCS
Deep Vein Thrombosis PROTECT
Dementia ADReCS
Dementia With Lewy Bodies ADReCS
Depressed Level Of Consciousness PROTECT
Depression PROTECT
Dermatitis ADReCS
Diabetes Mellitus ADReCS
Diabetic Coma PROTECT
Diabetic Ketoacidosis PROTECT
Diarrhoea ADReCS
Discomfort ADReCS
Disturbance In Attention PROTECT
Dizziness ADReCS
Dizziness Postural ADReCS
Drooling ADReCS
Drug Eruption ADReCS
Drug Withdrawal Syndrome PROTECT
Drug Withdrawal Syndrome Neonatal PROTECT
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Skin PROTECT
Dysarthria ADReCS
Dysgeusia PROTECT
Dyskinesia ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphonia PROTECT
Dyspnoea ADReCS
Dystonia ADReCS
Dysuria PROTECT
Ear Infection PROTECT
Ear Pain PROTECT
Eczema PROTECT
Ejaculation Disorder PROTECT
Elastosis Perforans SIDER
Elderly ADReCS
Electrocardiogram Abnormal ADReCS
Electrocardiogram Qt Corrected Interval Prolonged SIDER
Electrocardiogram Qt Prolonged ADReCS
Electrocardiogram T Wave Inversion SIDER
Embolism ADReCS
Embolism Venous PROTECT
Embolus SIDER
Endocrine Disorder SIDER
Eosinophil Count Increased PROTECT
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Eruption SIDER
Erythema ADReCS
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Eye Disorder SIDER
Eye Infection PROTECT
Eye Movement Disorder ADReCS
Eye Rolling ADReCS
Face Oedema PROTECT
Facial Spasm PROTECT
Faecal Incontinence PROTECT
Faecaloma PROTECT
Fall PROTECT
Fasting ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Flatulence ADReCS
Flushing PROTECT
Gait Disturbance PROTECT
Galactorrhoea ADReCS
Gamma-Glutamyltransferase Increased PROTECT
Gastric Disorder ADReCS
Gastroenteritis PROTECT
Gastrointestinal Disorder ADReCS
Gastrointestinal Obstruction ADReCS
Gastrointestinal Pain ADReCS
Generalised Oedema PROTECT
Glabellar Reflex Abnormal PROTECT
Glaucoma PROTECT
Glucose Increased SIDER
Glucose Urine Present PROTECT
Grand Mal Convulsion ADReCS
Gynaecomastia ADReCS
Haematocrit Decreased PROTECT
Haematology Test Abnormal ADReCS
Haemodynamic Test Abnormal ADReCS
Head Titubation PROTECT
Headache ADReCS
Hepatic Enzyme Increased PROTECT
High Density Lipoprotein Increased ADReCS
Hormone Level Abnormal SIDER
Hyperaemia ADReCS
Hyperaesthesia ADReCS
Hyperglycaemia ADReCS
Hyperinsulinaemia ADReCS
Hyperinsulinism ADReCS
Hyperkeratosis PROTECT
Hyperkinesia ADReCS
Hyperprolactinaemia ADReCS
Hypersensitivity ADReCS
Hypersomnia ADReCS
Hypertension ADReCS
Hypertonia ADReCS
Hypertriglyceridaemia ADReCS
Hyperventilation PROTECT
Hypoaesthesia PROTECT
Hypoglycaemia PROTECT
Hypokinesia ADReCS
Hypotension ADReCS
Hypothermia PROTECT
Immune System Disorder SIDER
Impaired Fasting Glucose ADReCS
Inappropriate Antidiuretic Hormone Secretion PROTECT
Incontinence ADReCS
Increased Appetite ADReCS
Induration ADReCS
Infection ADReCS
Infestation SIDER
Infestation Nos SIDER
Influenza PROTECT
Initial Insomnia SIDER
Injection Site Abscess PROTECT
Injection Site Cellulitis PROTECT
Injection Site Cyst PROTECT
Injection Site Haematoma PROTECT
Injection Site Induration PROTECT
Injection Site Necrosis PROTECT
Injection Site Nodule PROTECT
Injection Site Pain ADReCS
Injection Site Pruritus PROTECT
Injection Site Reaction ADReCS
Injection Site Ulcer PROTECT
Insomnia ADReCS
Insulin C-Peptide Abnormal ADReCS
Intestinal Obstruction ADReCS
Ischaemia ADReCS
Jaundice PROTECT
Joint Stiffness ADReCS
Joint Swelling PROTECT
Lacrimation Increased PROTECT
Laryngospasm PROTECT
Lethargy ADReCS
Leukopenia ADReCS
Libido Decreased PROTECT
Loss Of Consciousness ADReCS
Low Density Lipoprotein Increased ADReCS
Malaise PROTECT
Malignant Syndrome Nos SIDER
Mania PROTECT
Masked Facies ADReCS
Mediastinal Disorder SIDER
Menstrual Disorder ADReCS
Menstruation Delayed ADReCS
Menstruation Irregular ADReCS
Mental Disorder SIDER
Metabolic Disorder ADReCS
Middle Insomnia PROTECT
Movement Disorder ADReCS
Movements Involuntary SIDER
Muscle Contractions Involuntary ADReCS
Muscle Contracture ADReCS
Muscle Rigidity ADReCS
Muscle Spasms ADReCS
Muscle Tightness ADReCS
Muscle Twitching ADReCS
Muscular Weakness PROTECT
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myoclonus ADReCS
Myotonia PROTECT
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Pain ADReCS
Nervous System Disorder ADReCS
Nervousness PROTECT
Neuroleptic Malignant Syndrome ADReCS
Neutropenia ADReCS
Nightmare ADReCS
Nuchal Rigidity ADReCS
Obstruction ADReCS
Ocular Hyperaemia PROTECT
Oculogyric Crisis ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oligomenorrhoea PROTECT
Onychomycosis PROTECT
Opisthotonus ADReCS
Oromandibular Dystonia ADReCS
Oropharyngeal Pain ADReCS
Oropharyngeal Spasm PROTECT
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Pain ADReCS
Pain During Injection SIDER
Pain In Extremity ADReCS
Palpitations ADReCS
Pancreatitis PROTECT
Paraesthesia PROTECT
Paralysis ADReCS
Parkinsonian Gait ADReCS
Parkinsonian Rest Tremor PROTECT
Parkinsonism ADReCS
Periorbital Oedema ADReCS
Pharyngolaryngeal Pain SIDER
Photophobia PROTECT
Pleurothotonus PROTECT
Pneumonia ADReCS
Pneumonia Aspiration ADReCS
Pollakiuria PROTECT
Polydipsia PROTECT
Postural Orthostatic Tachycardia Syndrome SIDER
Posture Abnormal PROTECT
Priapism ADReCS
Protrusion Tongue ADReCS
Pruritus ADReCS
Pruritus Generalised ADReCS
Psychomotor Hyperactivity ADReCS
Psychotic Disorder ADReCS
Pulmonary Congestion PROTECT
Pulmonary Embolism ADReCS
Purpura ADReCS
Pyrexia PROTECT
Rales PROTECT
Rash ADReCS
Rash Papular ADReCS
Redness SIDER
Respiratory Tract Congestion PROTECT
Respiratory Tract Infection ADReCS
Restless Legs Syndrome ADReCS
Restlessness ADReCS
Retrograde Ejaculation ADReCS
Rhabdomyolysis PROTECT
Rhinitis ADReCS
Salivary Hypersecretion ADReCS
Schizoaffective Disorder ADReCS
Seborrhoeic Dermatitis PROTECT
Sedation ADReCS
Seizures SIDER
Sexual Dysfunction ADReCS
Shock ADReCS
Shoulder Pain ADReCS
Sinus Arrhythmia ADReCS
Sinus Tachycardia ADReCS
Sinusitis PROTECT
Skin Discolouration PROTECT
Sleep Apnoea Syndrome PROTECT
Sleep Disorder ADReCS
Small Intestinal Obstruction SIDER
Somnolence ADReCS
Stiffness SIDER
Stomach Discomfort ADReCS
Stroke ADReCS
Subcutaneous Abscess PROTECT
Sudden Death PROTECT
Suicidal Ideation ADReCS
Suicide SIDER
Suicide Attempt ADReCS
Swelling ADReCS
Swollen Tongue ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tardive Dyskinesia ADReCS
Temperature Regulation Disorder ADReCS
Tenderness ADReCS
Thirst PROTECT
Throat Tightness ADReCS
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thrombosis ADReCS
Thrombotic Thrombocytopenic Purpura ADReCS
Tinnitus PROTECT
Tongue Paralysis ADReCS
Tongue Spasm PROTECT
Tonsillitis PROTECT
Toothache ADReCS
Torsade De Pointes PROTECT
Torticollis ADReCS
Transaminases Increased PROTECT
Transient Ischaemic Attack ADReCS
Tremor ADReCS
Trismus ADReCS
Unresponsive To Stimuli PROTECT
Upper Respiratory Tract Infection ADReCS
Upset Stomach SIDER
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Infection ADReCS
Urine Analysis Abnormal ADReCS
Urticaria ADReCS
Vaginal Discharge PROTECT
Vascular Purpura ADReCS
Venous Thrombosis ADReCS
Ventricular Arrhythmia PROTECT
Ventricular Fibrillation PROTECT
Ventricular Tachycardia PROTECT
Vertigo ADReCS
Viral Infection ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Water Intoxication PROTECT
Weight Decreased ADReCS
Weight Increased ADReCS
Wheezing PROTECT
White Blood Cell Count Decreased PROTECT

InAADR: Drug-Protein-ADRs database