InAADR

Drug Information

Drug Name: Orlistat (96829-58-2)
PubChem ID: 3034010
SMILES: CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
InchiKey: AHLBNYSZXLDEJQ-FWEHEUNISA-N
Therapeutic Category: Anti-Obesity Agents, Central Nervous System Agents, Enzyme Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 495.745
LogP: 6.8819
Ring Count: 0
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 81.7

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Enalapril (75847-73-3) Intracranial Haemorrhage Antagonistic Not Understood Interaction between orlistat and antihypertensive drugs

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abdominal Rigidity MetaADEDB
Abdominal Strangulated Hernia MetaADEDB
Abnormal Faeces MetaADEDB
Abnormal Mammogram MetaADEDB
Abscess Intestinal MetaADEDB
Acinetobacter Infection MetaADEDB
Acne ADReCS
Acute Pancreatitis MetaADEDB
Acute Prerenal Failure MetaADEDB
Adenoiditis MetaADEDB
Adrenal Neoplasm MetaADEDB
Adverse Drug Effect MetaADEDB
Adverse Reaction MetaADEDB
Alanine Aminotransferase Abnormal MetaADEDB
Allergic Rhinitis MetaADEDB
Alopecia ADReCS
Altered Bowel Function MetaADEDB
Anal Discomfort MetaADEDB
Anal Fissure MetaADEDB
Anal Haemorrhage MetaADEDB
Anal Pruritus MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Androgen Deficiency MetaADEDB
Angina MetaADEDB
Angioedema ADReCS
Animal Bite MetaADEDB
Ankle Fracture MetaADEDB
Anogenital Warts MetaADEDB
Anorectal Discomfort ADReCS
Anorectal Disorder MetaADEDB
Anorexia MetaADEDB
Anticoagulation Drug Level Above Therapeutic MetaADEDB
Anticonvulsant Drug Level Decreased MetaADEDB
Antisocial Personality Disorder MetaADEDB
Anxiety ADReCS
Aortic Atherosclerosis MetaADEDB
Aortic Valve Calcification MetaADEDB
Apathy MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Appendectomy MetaADEDB
Appendicitis MetaADEDB
Appendicitis Perforated MetaADEDB
Appendix Disorder MetaADEDB
Appetite Disorder MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arthritis ADReCS
Arthropathy ADReCS
Asthenia ADReCS
Asthma ADReCS
Atrophy Of Skin MetaADEDB
Back Ache MetaADEDB
Back Disorder MetaADEDB
Back Injury MetaADEDB
Back Pain ADReCS
Bad Breath MetaADEDB
Belching MetaADEDB
Benign Neoplasm MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dyskinesia MetaADEDB
Biliary Tract Disorder MetaADEDB
Bilirubinuria MetaADEDB
Binge Eating MetaADEDB
Biopsy Breast Abnormal MetaADEDB
Biopsy Liver MetaADEDB
Bladder Discomfort MetaADEDB
Bleeding Hemorrhoids MetaADEDB
Bleeding Time Abnormal ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Iron Decreased MetaADEDB
Blood Test Abnormal MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urine Present MetaADEDB
Blood Viscosity Increased MetaADEDB
Bloody Discharge MetaADEDB
Body Fat Disorder MetaADEDB
Bone Spur MetaADEDB
Bowel Movement Irregularity MetaADEDB
Brain Concussion MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Stem Stroke MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Cancer MetaADEDB
Breast Cyst Excision MetaADEDB
Breast Disorder SIDER
Breast Lump MetaADEDB
Breast Lump Removal MetaADEDB
Breast Pain MetaADEDB
Breast Reconstruction MetaADEDB
Bronchitis MetaADEDB
Bronchospasm ADReCS
Bruxism MetaADEDB
Bullous Eruption ADReCS
Bunion MetaADEDB
Bunion Operation MetaADEDB
Bursitis MetaADEDB
Calculus Bladder MetaADEDB
Candidiasis Of Vagina MetaADEDB
Carcinoma Of The Cervix MetaADEDB
Carcinoma Of The Colon MetaADEDB
Cardiac Asthma MetaADEDB
Cardiac Perforation MetaADEDB
Cardiovascular Disorder ADReCS
Carotid Bruit MetaADEDB
Cellulitis MetaADEDB
Cerumen Impaction MetaADEDB
Cervical Discharge MetaADEDB
Cervical Polyp MetaADEDB
Cervicalgia MetaADEDB
Cervix Disorder MetaADEDB
Chest Infection MetaADEDB
Cholecystectomies MetaADEDB
Cholecystitis MetaADEDB
Cholecystitis Acute MetaADEDB
Cholecystitis Infective MetaADEDB
Cholelithiasis PROTECT
Chromaturia MetaADEDB
Closed Head Injury MetaADEDB
Coagulation Test Abnormal MetaADEDB
Coagulation Time Shortened MetaADEDB
Coccydynia MetaADEDB
Colectomy MetaADEDB
Colitis MetaADEDB
Colon Operation MetaADEDB
Colon Spastic MetaADEDB
Colonoscopy MetaADEDB
Complement Factor C3 Decreased MetaADEDB
Compulsive Shopping MetaADEDB
Congenital Hand Malformation MetaADEDB
Conjunctival Primary Acquired Melanosis MetaADEDB
Constipated MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Crying MetaADEDB
Crystal Urine MetaADEDB
Dandruff MetaADEDB
Death ADReCS
Defaecation Urgency ADReCS
Dengue Fever MetaADEDB
Dental Pain MetaADEDB
Dental Prosthesis User MetaADEDB
Depressed Mood MetaADEDB
Depression ADReCS
Depression Suicidal MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diarrhoea Infectious ADReCS
Dilatation Atrial MetaADEDB
Dilatation Ventricular MetaADEDB
Discomfort ADReCS
Dislocation MetaADEDB
Disorder Of Globe MetaADEDB
Distractibility MetaADEDB
Diverticulitis PROTECT
Dizziness ADReCS
Drug Ineffective MetaADEDB
Drug Interaction SIDER
Drug Level Changed MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Skin ADReCS
Dyschezia MetaADEDB
Dysentery SIDER
Dysgeusia MetaADEDB
Dyslipidaemia MetaADEDB
Dysmenorrhea MetaADEDB
Dysmorphism MetaADEDB
Dyspepsia MetaADEDB
Ear ADReCS
Ear Ache MetaADEDB
Ear Infection ADReCS
Early Morning Awakening MetaADEDB
Economic Problem MetaADEDB
Eczema Infected MetaADEDB
Electrocardiogram Q Wave Abnormal MetaADEDB
Electrocardiogram Q Waves MetaADEDB
Electrocardiogram T Wave Peaked MetaADEDB
Elevated Triglycerides MetaADEDB
Emergency Care Examination MetaADEDB
Emotional Disorder MetaADEDB
Emotional Distress MetaADEDB
Endometriosis MetaADEDB
Energy Increased MetaADEDB
Enteritis Infectious MetaADEDB
Eosinophilic Oesophagitis MetaADEDB
Epilepsy MetaADEDB
Eruption SIDER
Excessive Thirst MetaADEDB
Extremity Pain MetaADEDB
Eye Injury MetaADEDB
Eyelid Retraction MetaADEDB
Facet Joint Syndrome MetaADEDB
Facial Neuralgia MetaADEDB
Faecal Incontinence ADReCS
Faecal Volume Decreased MetaADEDB
Faecal Volume Increased MetaADEDB
Faeces Discoloured ADReCS
Faeces Pale MetaADEDB
Fallopian Tube Obstruction MetaADEDB
Fascitis Plantar MetaADEDB
Fat Intolerance MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Fatty Stools MetaADEDB
Feeling Abnormal MetaADEDB
Feeling Cold MetaADEDB
Feelings Of Worthlessness MetaADEDB
Female Genital Operation MetaADEDB
Fibroids MetaADEDB
Fibromyalgia MetaADEDB
Fibula Fracture MetaADEDB
Flatulence ADReCS
Flooding MetaADEDB
Flu MetaADEDB
Food Allergy MetaADEDB
Food Aversion MetaADEDB
Food Craving MetaADEDB
Food Poisoning MetaADEDB
Foot Fracture MetaADEDB
Frequent Bowel Movements ADReCS
Frustration MetaADEDB
Furuncle MetaADEDB
Gall Bladder MetaADEDB
Gallbladder Oedema MetaADEDB
Gallbladder Operation MetaADEDB
Gastric Disorder MetaADEDB
Gastric Infection MetaADEDB
Gastroenteritis Viral MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Hypermotility MetaADEDB
Gastrointestinal Infection MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Sounds Abnormal MetaADEDB
Gastrointestinal Symptom Nos SIDER
Genital Disorder Female MetaADEDB
Genital Herpes MetaADEDB
Gingival Disorder ADReCS
Global Amnesia MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glucose Intolerance MetaADEDB
Glycosylated Haemoglobin MetaADEDB
Gnathostomiasis MetaADEDB
Groin Abscess MetaADEDB
Haematochezia MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Haemorrhoids MetaADEDB
Hair Disease MetaADEDB
Hair Texture Abnormal MetaADEDB
Hand Fracture MetaADEDB
Hangover MetaADEDB
Hay Fever MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heart Transplant MetaADEDB
Heat Exhaustion MetaADEDB
Heat Stroke MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure ADReCS
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatojugular Reflux MetaADEDB
Hernia MetaADEDB
Hernia Pain MetaADEDB
Hormone Level Abnormal MetaADEDB
Hot Flash MetaADEDB
Hyperalimentation MetaADEDB
Hyperamylasaemia MetaADEDB
Hypereosinophilic Syndrome MetaADEDB
Hyperlipaemia MetaADEDB
Hypermetabolism MetaADEDB
Hyperproteinaemia MetaADEDB
Hypersensitivity ADReCS
Hypertonia MetaADEDB
Hypoglycaemia ADReCS
Hypoglycaemia Neonatal MetaADEDB
Hypomenorrhea MetaADEDB
Hypometabolism MetaADEDB
Hypothyroid MetaADEDB
Hypothyroidism ADReCS
Hypovitaminosis MetaADEDB
Hysterectomy MetaADEDB
Ill-Defined Disorder MetaADEDB
Immunosuppressant Drug Level Decreased MetaADEDB
Impatience MetaADEDB
Impingement Syndrome MetaADEDB
Incision Site Complication MetaADEDB
Incision Site Haemorrhage MetaADEDB
Incision Site Pain MetaADEDB
Incontinence ADReCS
Increased Appetite MetaADEDB
Infected Cyst MetaADEDB
Infected Insect Bite MetaADEDB
Infection ADReCS
Infection Upper Respiratory MetaADEDB
Infection Viral MetaADEDB
Infectious Mononucleosis MetaADEDB
Influenza ADReCS
Infrequent Bowel Movements MetaADEDB
Ingrowing Nail MetaADEDB
Initial Insomnia MetaADEDB
Injection Site Burning MetaADEDB
International Normalised Ratio Increased ADReCS
Intertrigo Candida MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Cyst MetaADEDB
Intestinal Functional Disorder MetaADEDB
Intestinal Malrotation MetaADEDB
Intestinal Obstruction MetaADEDB
Intestinal Polyp MetaADEDB
Irregular Menstrual Cycle MetaADEDB
Joint Injury MetaADEDB
Joint Sprain MetaADEDB
Jugular Vein Distension MetaADEDB
Kidney Fibrosis MetaADEDB
Kidney Infection MetaADEDB
Kidney Pain MetaADEDB
Lack Of Satiety MetaADEDB
Lactescent Serum MetaADEDB
Laparoscopic Surgery MetaADEDB
Laziness MetaADEDB
Ligament Rupture MetaADEDB
Ligament Sprain MetaADEDB
Limb Discomfort MetaADEDB
Limb Injury MetaADEDB
Lip Pain MetaADEDB
Liver Transplant PROTECT
Local Swelling MetaADEDB
Lower Respiratory Tract Infection ADReCS
Lymphocytic Infiltration MetaADEDB
Magnesium Deficiency MetaADEDB
Malabsorption MetaADEDB
Marital Problem MetaADEDB
Medial Tibial Stress Syndrome MetaADEDB
Mediastinitis MetaADEDB
Medical Diet MetaADEDB
Meningitides MetaADEDB
Menopausal Disorder ADReCS
Menopausal Symptoms ADReCS
Menopause ADReCS
Menstrual Disorder MetaADEDB
Menstruation Delayed MetaADEDB
Menstruation Irregular ADReCS
Mental Disorder SIDER
Mental Impairment MetaADEDB
Mesangioproliferative Glomerulonephritis MetaADEDB
Metrorrhagia ADReCS
Micturition Urgency MetaADEDB
Migraine MetaADEDB
Modified Radical Mastectomy MetaADEDB
Mucous Stools MetaADEDB
Multiple Allergies MetaADEDB
Multiple Injuries MetaADEDB
Muscle Injury MetaADEDB
Muscle Spasms ADReCS
Muscle Strain MetaADEDB
Muscle Tightness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain MetaADEDB
Myalgia ADReCS
Mycosis Fungoides MetaADEDB
Mycotic Allergy MetaADEDB
Nail Disorder ADReCS
Nail Operation MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Negative Thoughts MetaADEDB
Nephrolithiasis MetaADEDB
Nerve Block MetaADEDB
Nervous Tension MetaADEDB
No Match PROTECT
Nocturia MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Nonspecific Reaction MetaADEDB
Nose And Throat Examination ADReCS
Obsessive Thoughts MetaADEDB
Occult Blood MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oily Skin SIDER
Oligodipsia MetaADEDB
Oligomenorrhea MetaADEDB
Onychoclasis MetaADEDB
Optic Neuritis MetaADEDB
Oral Herpes MetaADEDB
Oral Mucosal Blistering MetaADEDB
Organic Erectile Dysfunction MetaADEDB
Osteoarthritis ADReCS
Osteopenia MetaADEDB
Otitis SIDER
Pain ADReCS
Pain In Extremity ADReCS
Pancreatic Enzymes Increased MetaADEDB
Pancreatitis ADReCS
Papilloma Viral Infection MetaADEDB
Paraesthesia ADReCS
Pedal Edema ADReCS
Perirectal Abscess MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngitis Streptococcal MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Photosensitive Rash MetaADEDB
Pms MetaADEDB
Poikilocytosis MetaADEDB
Pollakiuria MetaADEDB
Polycystic Ovaries MetaADEDB
Polysubstance Dependence MetaADEDB
Poor Quality Sleep MetaADEDB
Post Procedural Swelling MetaADEDB
Postmenopausal Bleeding MetaADEDB
Postpartum Disorder MetaADEDB
Prinzmetal Angina MetaADEDB
Procedural Nausea MetaADEDB
Proctalgia ADReCS
Prothrombin Level Decreased ADReCS
Pruritus ADReCS
Pulmonary Arterial Pressure Increased MetaADEDB
Pulmonary Thrombosis MetaADEDB
Pulmonary Valve Incompetence MetaADEDB
Pulse Abnormal MetaADEDB
Rash ADReCS
Rectal Discharge PROTECT
Rectal Fissure MetaADEDB
Rectal Haemorrhage PROTECT
Rectal Prolapse MetaADEDB
Rectal Spasm MetaADEDB
Rectal Tenesmus MetaADEDB
Recurrent Cancer MetaADEDB
Renal Failure PROTECT
Respiratory Disorder ADReCS
Respiratory Tract Infection ADReCS
Rhinorrhea MetaADEDB
Right Atrial Dilatation MetaADEDB
Salt Craving MetaADEDB
Scan Lymph Nodes MetaADEDB
Scleral Discolouration MetaADEDB
Scrotal Swelling MetaADEDB
Seborrhoea ADReCS
Seborrhoeic Dermatitis SIDER
Self-Injurious Ideation MetaADEDB
Sensation Of Heaviness MetaADEDB
Sigmoidectomy MetaADEDB
Sigmoiditis MetaADEDB
Sinus Disorder MetaADEDB
Sinus Headache MetaADEDB
Sinusitis MetaADEDB
Skeletal Injury MetaADEDB
Skin Laceration MetaADEDB
Skin Odour Abnormal MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder ADReCS
Sleep Talking MetaADEDB
Social Avoidant Behaviour MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Disorder MetaADEDB
Spondylosis MetaADEDB
Starvation MetaADEDB
Stasis Dermatitis MetaADEDB
Steatorrhoea ADReCS
Streptococcal Infection MetaADEDB
Stress MetaADEDB
Stress Incontinence MetaADEDB
Subcutaneous Abscess MetaADEDB
Surgery MetaADEDB
Temperature Regulation Disorder MetaADEDB
Tendonitis ADReCS
Tension Headache MetaADEDB
Therapeutic Response Unexpected MetaADEDB
Thyroid Cancer MetaADEDB
Thyroid Disease MetaADEDB
Thyroid Neoplasia MetaADEDB
Thyroiditis MetaADEDB
Tobacco User MetaADEDB
Tongue Biting MetaADEDB
Tongue Discolouration MetaADEDB
Tonsillitis MetaADEDB
Tooth Disorder ADReCS
Transaminases Increased ADReCS
Tuberculin Test Positive MetaADEDB
Type 2 Diabetes Mellitus ADReCS
Upper Respiratory Tract Infection ADReCS
Urethral Disorder SIDER
Urethral Haemorrhage MetaADEDB
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urine Odour Abnormal MetaADEDB
Urticaria ADReCS
Uterine Cyst MetaADEDB
Uterine Pain MetaADEDB
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vitamin K Deficiency MetaADEDB
Volume Blood Decreased MetaADEDB
Volvulus MetaADEDB
Vomiting ADReCS
Waist Circumference Increased MetaADEDB
Weight Fluctuation MetaADEDB
Weight Gain MetaADEDB
Wisdom Teeth Removal MetaADEDB

InAADR: Drug-Protein-ADRs database