| Drug Name: | Nitrofurantoin (67-20-9) |
|---|---|
| PubChem ID: | 6604200 |
| SMILES: | C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-] |
| InchiKey: | NXFQHRVNIOXGAQ-YCRREMRBSA-N |
| Therapeutic Category: | Anti-Infective Agents, Renal Agents |
| Molecular Weight (dalton) | : | 238.159 |
| LogP | : | 0.0735 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 118.05 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Phenytoin (57-41-0) | Seizure Control Lost | Antagonistic | Not understood | Interaction of nitrofurantoin with diphenylhydantoin |
| Fluconazole (86386-73-4) | Pulmonary Toxicity | Additive | Not fully understood | Pulmonary and hepatic toxicity due to nitrofurantoin and fluconazole treatment |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category