InAADR

Drug Information

Drug Name: Nadolol (42200-33-9)
PubChem ID: 39147
SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1C[C@@H]([C@@H](C2)O)O)O
InchiKey: VWPOSFSPZNDTMJ-UCWKZMIHSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Antagonists, Adrenergic beta-Antagonists, Anti-Arrhythmia Agents, Antihypertensive Agents, Autonomic Agents, Cardiovascular Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Sympatholytics

Computed Drug Properties

Molecular Weight (dalton): 309.406
LogP: 0.6348
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 81.95

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Increased Beta-Blockade CYP2D6 (P10635) Increased beta-blockade [ ADR Type 1 ] Drugs in special patient groups: clinical importance of genomics in drug effects In: Carruthers GS, Hoffmann BB,Melmon KL, Nierenberg DW

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension SIDER
Abdominal Distension ADReCS
Abnormal Behaviour ADReCS
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Ache SIDER
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Affect Lability ADReCS
Age Indeterminate Myocardial Infarction MetaADEDB
Agoraphobia MetaADEDB
Agranulocytosis ADReCS
Agraphia MetaADEDB
Akathisia Drug-Induced MetaADEDB
Alcohol Consumption MetaADEDB
Alcoholic Cirrhosis MetaADEDB
Allergic Alveolitis MetaADEDB
Allergic Rhinitis MetaADEDB
Alopecia ADReCS
Amentia MetaADEDB
Ammonia Increased MetaADEDB
Amnesia ADReCS
Anaemia MetaADEDB
Anal Fissure MetaADEDB
Analgesia MetaADEDB
Anaphylactic Reaction MetaADEDB
Anorexia ADReCS
Antidepressant Drug Level Increased MetaADEDB
Anxiety MetaADEDB
Aortic Dissection MetaADEDB
Aortic Valve Sclerosis MetaADEDB
Application Site Discolouration MetaADEDB
Aptyalism MetaADEDB
Areflexia MetaADEDB
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stenosis MetaADEDB
Arterial Thrombosis ADReCS
Arteriosclerotic Heart Disease MetaADEDB
Arthritis Infective MetaADEDB
Arthroscopy MetaADEDB
Ascites MetaADEDB
Asthenia ADReCS
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrial Fibrillation MetaADEDB
Atrioventricular Block ADReCS
Atrioventricular Block Complete ADReCS
Atrioventricular Block First Degree MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Barrett Oesophagus MetaADEDB
Basedow Disease MetaADEDB
Bladder Neck Obstruction MetaADEDB
Blepharospasm MetaADEDB
Block Heart SIDER
Blood Albumin Increased MetaADEDB
Blood Iron Decreased MetaADEDB
Blood Iron Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Body Temperature Increased ADReCS
Bradycardia ADReCS
Brain Damage MetaADEDB
Breast Enlargement MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchitis MetaADEDB
Bronchospasm ADReCS
Bursitis MetaADEDB
Cardiac Aneurysm MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cartilage Development Disorder MetaADEDB
Cataract Operation MetaADEDB
Catatonia ADReCS
Cellulitis MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Pain MetaADEDB
Chill MetaADEDB
Choking Sensation MetaADEDB
Chromaturia MetaADEDB
Cirrhosis MetaADEDB
Claustrophobia MetaADEDB
Cold Extremities MetaADEDB
Cold Sweat MetaADEDB
Colitis ADReCS
Colitis Ischaemic ADReCS
Colon Cancer Metastatic MetaADEDB
Colpitis MetaADEDB
Complication Of Device Insertion MetaADEDB
Condition Aggravated MetaADEDB
Congenital Heart Disease MetaADEDB
Conjunctival Deposit MetaADEDB
Constipation ADReCS
Coronary Artery Disease MetaADEDB
Costovertebral Angle Tenderness MetaADEDB
Cough ADReCS
Cutaneous Mycosis MetaADEDB
Cyanopsia MetaADEDB
Cyst Rupture MetaADEDB
Cystitis Interstitial MetaADEDB
Decreased Appetite ADReCS
Decreased Libido MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Dental Abscess MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Allergic ADReCS
Diabetes MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Foot Infection MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Dilatation Ventricular MetaADEDB
Discomfort ADReCS
Disorder Peripheral Vascular MetaADEDB
Disorder Retinal MetaADEDB
Disorientation ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Tolerance MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Dysarthria ADReCS
Dyspepsia ADReCS
Early Morning Awakening MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy MetaADEDB
Erectile Dysfunction ADReCS
Esophageal And Gastric Varices MetaADEDB
Excess Potassium MetaADEDB
Excoriation MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Oedema MetaADEDB
Eye Pruritus MetaADEDB
Facial Flushing MetaADEDB
Facial Swelling ADReCS
Fatigue ADReCS
Feeling Cold MetaADEDB
Fibula Fracture MetaADEDB
Flashing Lights MetaADEDB
Flatulence ADReCS
Foot Amputation MetaADEDB
Fractured Sacrum MetaADEDB
Fungaemia MetaADEDB
Fungal Oesophagitis MetaADEDB
Gall Bladder MetaADEDB
Gambling MetaADEDB
Gastric Antral Vascular Ectasia MetaADEDB
Gastrointestinal Hemorrhage MetaADEDB
Gingival Hemorrhage MetaADEDB
Gout MetaADEDB
Haematochezia MetaADEDB
Haemodynamic Instability MetaADEDB
Haemorrhage Rectum MetaADEDB
Hallucination ADReCS
Headache ADReCS
Heart Rate Decreased ADReCS
Hepatic Enzyme Increased ADReCS
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis C MetaADEDB
High Frequency Ablation MetaADEDB
Hilar Lymphadenopathy MetaADEDB
Hip Surgery MetaADEDB
Hodgkin Disease MetaADEDB
Hot Flash MetaADEDB
Hyperhidrosis ADReCS
Hypertension ADReCS
Hypertensive SIDER
Hyperthyroidism MetaADEDB
Hypertonia MetaADEDB
Hypertrichosis MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypoxia MetaADEDB
Immune Reconstitution Syndrome MetaADEDB
Immunosuppressant Drug Level MetaADEDB
Implant Site Pain MetaADEDB
Incoherent MetaADEDB
Incorrect Dose Administered MetaADEDB
Injection Site Erythema MetaADEDB
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
Intestinal Polyp MetaADEDB
Joint Injury MetaADEDB
Joint Stiffness MetaADEDB
Knee Arthroplasty MetaADEDB
Lacrimation Increased MetaADEDB
Laryngeal Inflammation MetaADEDB
Laryngospasm ADReCS
Laxative Abuse MetaADEDB
Left Atrial Dilatation MetaADEDB
Lethargy MetaADEDB
Leukopenia Neonatal MetaADEDB
Libido Decreased ADReCS
Lipids Increased MetaADEDB
Lung Neoplasm MetaADEDB
Lymphocytes Decreased MetaADEDB
Madarosis MetaADEDB
Malignant Hypertension MetaADEDB
Melanocytic Naevus MetaADEDB
Memory Loss SIDER
Mental Status Changes MetaADEDB
Mesenteric Artery Thrombosis ADReCS
Metabolic Encephalopathy MetaADEDB
Microalbuminuria MetaADEDB
Micturition Urgency MetaADEDB
Mood Swings ADReCS
Movement Disorder MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Tightness MetaADEDB
Musculoskeletal Pain MetaADEDB
Nasal Congestion ADReCS
Nasal Sinus Congestion MetaADEDB
Nausea ADReCS
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Neuromuscular Block Prolonged MetaADEDB
Neuropsychological Test Abnormal ADReCS
Ocular Vascular Disorder MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Off Label Use MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Osteoarthritis ADReCS
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palpitation MetaADEDB
Palsies MetaADEDB
Panic Attack MetaADEDB
Paraesthesia ADReCS
Pemphigoid ADReCS
Pericardial Effusion MetaADEDB
Peyronie Disease ADReCS
Phaeochromocytoma ADReCS
Phimosis MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pollakiuria MetaADEDB
Polycystic Ovaries MetaADEDB
Poor Quality Drug Administered MetaADEDB
Poor Quality Sleep MetaADEDB
Portal Hypertension MetaADEDB
Portal Vein Thrombosis MetaADEDB
Procedural Complication MetaADEDB
Productive Cough MetaADEDB
Pruritus ADReCS
Psychosexual Disorder MetaADEDB
Pulmonary Hypertension MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Purpura ADReCS
Purpura Non-Thrombocytopenic ADReCS
Rash ADReCS
Raynaud Disease SIDER
Raynaud Phenomenon SIDER
Renal Atrophy MetaADEDB
Renal Impairment MetaADEDB
Respiratory Distress ADReCS
Respiratory Rate Increased MetaADEDB
Respiratory Sounds MetaADEDB
Rheumatoid Factor Increased MetaADEDB
Sedation ADReCS
Sensory Loss MetaADEDB
Sinus Bradycardia MetaADEDB
Skin Discolouration MetaADEDB
Sleep Apnea MetaADEDB
Sleep Disorder ADReCS
Sleep Disturbance SIDER
Slurred Speech SIDER
Smoker MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Fracture MetaADEDB
Spinning Sensation MetaADEDB
Staphylococcal Abscess MetaADEDB
Stress MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sweating SIDER
Swelling ADReCS
Swelling Face ADReCS
Swollen Tongue MetaADEDB
Tachycardia MetaADEDB
Tachycardia Supraventricular MetaADEDB
Tachycardia Ventricular MetaADEDB
Tenderness ADReCS
Thought Blocking MetaADEDB
Throat Sore SIDER
Thrombosis ADReCS
Tinnitus ADReCS
Torsade De Pointes MetaADEDB
Treatment Noncompliance MetaADEDB
Tremor MetaADEDB
Urosepsis MetaADEDB
Vaginal Swelling MetaADEDB
Vascular Insufficiency ADReCS
Vascular Purpura ADReCS
Ventricular Fibrillation MetaADEDB
Violence-Related Symptom MetaADEDB
Vision Blurred ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vitamin B12 Increased MetaADEDB
Vomiting ADReCS
Vulvovaginal Discomfort MetaADEDB
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS

InAADR: Drug-Protein-ADRs database