This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug |
Toxicity |
Interaction Type |
Mechanism |
Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity |
Interacting Protein |
Mechanism |
Reference |
| Hepatotoxicity | Cytochrome P450 2E1 (P05181) | Sevoflurane is metabolized by P-450 2E1@ so pathophysiologic factors and drug interactions altering P-450 2E1 activity will also influence sevoflurane metabolism (52) The extent of metabolism of sevoflurane@ 2% to 5%@ is less than that of all other volatile anesthetics except isoflurane and desflurane@ which might be associated with idiosyncratic hepatotoxicity [ ADR Type 2 ] | Biotransformation of sevoflurane
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This panel provides drug-food interactions and their ADRs along with references
This panel provides information on drug category