InAADR

Drug Information

Drug Name: Meropenem (119478-56-7)
PubChem ID: 441130
SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O
InchiKey: DMJNNHOOLUXYBV-PQTSNVLCSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 383.47
LogP: -0.308
Ring Count: 0
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 110.18

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Valproic Acid (99-66-1) Seizures Antagonistic Unknown Pharmacokinetic interaction between valproic acid and meropenem

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Distension ADReCS
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abdominal Sepsis MetaADEDB
Abnormal Vision MetaADEDB
Abscess Bacterial MetaADEDB
Accidental Injury ADReCS
Acidosis MetaADEDB
Actinomycosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Activated Partial Thromboplastin Time Shortened ADReCS
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenoma MetaADEDB
Adenopathy MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Altered State Of Consciousness MetaADEDB
Anaemia ADReCS
Anaphylactic Reaction MetaADEDB
Anaphylactic Shock ADReCS
Aneurysm Ruptured MetaADEDB
Angioedema ADReCS
Angiopathy ADReCS
Anorexia ADReCS
Anosmia MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Apnea MetaADEDB
Apnoea ADReCS
Arthritis Infective MetaADEDB
Ascites MetaADEDB
Ascites Infection MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Aspergillosis MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Asystole MetaADEDB
Atelectasis MetaADEDB
Back Pain ADReCS
Bacterial Disease Carrier MetaADEDB
Bacterial Infection ADReCS
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Fibrosis MetaADEDB
Biopsy Liver Abnormal MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Injury MetaADEDB
Blast Cell Count Increased MetaADEDB
Blindness Unilateral MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Amylase Increased MetaADEDB
Blood Beta-D-Glucan Increased MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholinesterase Decreased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Culture Positive MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Osmolarity Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Abnormal MetaADEDB
Blood Urea Abnormal MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Urea Increased ADReCS
Blood Urine Present MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Failure MetaADEDB
Bone Swelling MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Bradycardia ADReCS
Brain Death MetaADEDB
Bronchial Haemorrhage MetaADEDB
Bronchoalveolar Lavage MetaADEDB
Bronchopneumonia MetaADEDB
Bundle Branch Block Left MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Sepsis MetaADEDB
Candidiasis ADReCS
Candidiasis Of Mouth MetaADEDB
Cardiac Arrest ADReCS
Cardiac Failure ADReCS
Cardiac Fibrillation MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Central Nervous System Infection SIDER
Central Nervous System Lesion MetaADEDB
Cerebellar Infarction MetaADEDB
Cerebral Haemorrhage MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Chloroma MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Cholestasis ADReCS
Chromaturia ADReCS
Chronic Left Ventricular Failure MetaADEDB
Citrobacter Infection MetaADEDB
Clotting MetaADEDB
Cmv Infection MetaADEDB
Colitis ADReCS
Colitis Pseudomembranous MetaADEDB
Complications Of Transplanted Liver MetaADEDB
Confusional State ADReCS
Constipation ADReCS
Convulsion ADReCS
Coombs Test Positive ADReCS
Corneal Clouding MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Creatinine Increased SIDER
Cyst MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Delirium ADReCS
Depressed Level Of Consciousness MetaADEDB
Depressed Mood MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Detached Retina MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diffuse Large B-Cell Lymphoma MetaADEDB
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drug Interaction SIDER
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Dyspnoea Exacerbated MetaADEDB
Dysuria ADReCS
Effusion ADReCS
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Embolism ADReCS
Embolus SIDER
Encephalitis Viral MetaADEDB
Encephalopathy MetaADEDB
Enlarged Liver MetaADEDB
Enlargement Abdomen SIDER
Enterococcal Infection MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased ADReCS
Eosinophilia ADReCS
Eosinophilic Pneumonia Chronic MetaADEDB
Epistaxis ADReCS
Erosive Oesophagitis MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Escherichia Infection MetaADEDB
Esophageal Ulcer MetaADEDB
Exfoliative Rash MetaADEDB
Eye Rolling MetaADEDB
Eyelid Margin Crusting MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Fibrin D Dimer MetaADEDB
Fibrin Increased MetaADEDB
Fistula Discharge MetaADEDB
Flatulence ADReCS
Fluid Overload ADReCS
Fungal Disease MetaADEDB
Fungus Serology Test Positive MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Hypomotility MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Glossitis ADReCS
Granulocyte Count Decreased MetaADEDB
Haematocrit Decreased ADReCS
Haemoglobin ADReCS
Haemoglobin Decreased ADReCS
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Haemorrhagic Ascites ADReCS
Hallucination ADReCS
Headache ADReCS
Heart Rate Abnormal MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal MetaADEDB
Hepatitis ADReCS
Hepatitis Fulminant MetaADEDB
Hereditary Spastic Paraplegia MetaADEDB
Herpes Ophthalmic MetaADEDB
Hiccough MetaADEDB
Hiv Disease MetaADEDB
Hypercapnia MetaADEDB
Hyperchloraemia MetaADEDB
Hypercoagulation MetaADEDB
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertrophy ADReCS
Hypervolaemia ADReCS
Hypoaesthesia MetaADEDB
Hypochromic Anaemia ADReCS
Hypogammaglobulinaemia MetaADEDB
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypokinesia MetaADEDB
Hypomagnesaemia ADReCS
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Hypoxia ADReCS
Ild MetaADEDB
Ileus ADReCS
Ill-Defined Disorder ADReCS
Immunodeficiency Common Variable MetaADEDB
Incontinence ADReCS
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection In An Immunocompromised Host MetaADEDB
Infection Susceptibility Increased MetaADEDB
Inflammation ADReCS
Injection Site Inflammation ADReCS
Injection Site Oedema ADReCS
Injection Site Pain ADReCS
Injection Site Reaction ADReCS
Insomnia ADReCS
Intestinal Obstruction ADReCS
Intestinal Perforation MetaADEDB
Intravascular Haemolysis MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Kidney Failure MetaADEDB
Klebsiella Infection MetaADEDB
Laceration MetaADEDB
Leucopenia MetaADEDB
Leukocytosis ADReCS
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Lipase MetaADEDB
Loss Of Consciousness ADReCS
Lung Edema MetaADEDB
Lung Hyperinflation MetaADEDB
Lung Infection Pseudomonal MetaADEDB
Lyell MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphoma MetaADEDB
Lymphoplasmacytoid Lymphoma/Immunocytoma MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Melaena ADReCS
Meningitides MetaADEDB
Meningitis Listeria MetaADEDB
Metastatic Neoplasm MetaADEDB
Middle Ear Inflammation MetaADEDB
Miosis MetaADEDB
Mitral Valve Prolapse MetaADEDB
Monocyte Percentage Decreased MetaADEDB
Monocyte Percentage Increased MetaADEDB
Motor Dysfunction MetaADEDB
Mouth Ulcer MetaADEDB
Mucosal Inflammation MetaADEDB
Mucosal Ulceration MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Necrosis MetaADEDB
Myocardial Infarction ADReCS
Nausea ADReCS
Necrolysis Epidermal SIDER
Nervousness ADReCS
Neumonia MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neurosis MetaADEDB
Neutropenia ADReCS
Neutropenic Sepsis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Obliterative Bronchiolitis MetaADEDB
Obstruction ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oligohydramnios MetaADEDB
Oliguria MetaADEDB
Oral Candidiasis ADReCS
Oral Herpes MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain During Injection SIDER
Pancreatitis MetaADEDB
Paraesthesia ADReCS
Pathogen Resistance MetaADEDB
Pco2 Decreased MetaADEDB
Pelvic Pain ADReCS
Pericardial Effusion MetaADEDB
Peripheral Vascular Disorder ADReCS
Perirectal Abscess MetaADEDB
Peritoneal Haemorrhage ADReCS
Peritoneal Tuberculosis MetaADEDB
Peritonitis MetaADEDB
Pharyngitis ADReCS
Pharyngolaryngeal Pain MetaADEDB
Phlebitis ADReCS
Platelet Count MetaADEDB
Platelet Count Decreased ADReCS
Platelet Count Increased ADReCS
Pleural Adhesion MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumococcal Infection MetaADEDB
Pneumonia ADReCS
Pneumonia Cytomegaloviral MetaADEDB
Pneumonia Klebsiella MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumothorax MetaADEDB
Polyneuropathy MetaADEDB
Polyuria MetaADEDB
Postoperative Infection MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pseudomembranous Colitis ADReCS
Pseudomonas Infection MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Embolism ADReCS
Pulmonary Function Test Decreased MetaADEDB
Pulmonary Oedema ADReCS
Pus In Stool MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Red Blood Cells Urine Positive ADReCS
Red Urine SIDER
Renal Abscess MetaADEDB
Renal Failure ADReCS
Renal Impairment ADReCS
Respiratory Disorder ADReCS
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Rhabdomyolysis MetaADEDB
Right Atrial Dilatation MetaADEDB
Scar MetaADEDB
Seizures SIDER
Sensory Disturbance MetaADEDB
Sepsis ADReCS
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Shock ADReCS
Shock Haemorrhagic MetaADEDB
Sickness SIDER
Skin Swelling MetaADEDB
Skin Ulcer ADReCS
Small Intestinal Haemorrhage MetaADEDB
Somnolence ADReCS
Sputum Culture Positive MetaADEDB
Staphylococcal Skin Infection MetaADEDB
Stem Cell Transplant MetaADEDB
Stenotrophomonas Sepsis MetaADEDB
Stevens-Johnson Syndrome ADReCS
Streptococcal Bacteraemia MetaADEDB
Sudden Cardiac Death MetaADEDB
Sweating SIDER
Syncope ADReCS
Tachycardia ADReCS
Tension ADReCS
Thrombocytopenia ADReCS
Thrombocytosis ADReCS
Thrombophlebitis ADReCS
Thrombosis In Device MetaADEDB
Tooth Extraction MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Encephalopathy MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Tracheobronchitis MetaADEDB
Transaminases Increased MetaADEDB
Tricuspid Valve Disease MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Ulcer ADReCS
Ureteric Cancer MetaADEDB
Urinary Incontinence ADReCS
Urinary Tract Infection Fungal MetaADEDB
Urosepsis MetaADEDB
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vaginal Moniliasis SIDER
Vanishing Bile Duct Syndrome MetaADEDB
Vascular Graft Occlusion MetaADEDB
Vertigo Positional MetaADEDB
Viral Rash MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Mycotic Infection ADReCS
White Blood Cell Count Decreased ADReCS
Wound Secretion MetaADEDB

InAADR: Drug-Protein-ADRs database