Drug Name: | Levofloxacin (100986-85-4) |
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PubChem ID: | 149096 |
SMILES: | C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O |
InchiKey: | GSDSWSVVBLHKDQ-JTQLQIEISA-N |
Therapeutic Category: | Anti-Infective Agents |
Molecular Weight (dalton) | : | 361.373 |
LogP | : | 1.544 |
Ring Count | : | 2 |
Hydrogen Bond Acceptor Count | : | 6 |
Hydrogen Bond Donor Count | : | 1 |
Total Polar Surface Area | : | 75.01 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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Amiodarone (1951-25-3) | Torsade De Pointes | Additive | Not established | Quinolone-induced QT interval prolongation: a not-so-unexpected class effect |
Warfarin (81-81-2) | Bleeding | Antagonistic | Uncertain. It is not clear what factors might have been responsible in those cases where the effects of the anticoagulants were increased | Adverse reaction reporting of interaction between warfarin and fluoroquinolones |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category