InAADR

Drug Information

Drug Name: Lacidipine (103890-78-4)
PubChem ID: 5311217
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2/C=C/C(=O)OC(C)(C)C)C(=O)OCC)C)C
InchiKey: GKQPCPXONLDCMU-CCEZHUSRSA-N
Therapeutic Category: Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators

Computed Drug Properties

Molecular Weight (dalton): 455.551
LogP: 4.4025
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 90.93

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Acantholysis MetaADEDB
Accident MetaADEDB
Acidosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Afib MetaADEDB
Aggression MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Alopecia MetaADEDB
Angina MetaADEDB
Anisocoria MetaADEDB
Anticholinergic Syndrome MetaADEDB
Apoplexy MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriovenous Fistula Thrombosis MetaADEDB
Arthropathy MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Asthmatic Crisis MetaADEDB
Ataxia MetaADEDB
Autoimmune Disorder MetaADEDB
Black Stools MetaADEDB
Bladder Retention MetaADEDB
Blood Creatine Abnormal MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Bone Disorder MetaADEDB
Bradyarrhythmia MetaADEDB
Brain Oedema MetaADEDB
Bulbar Palsy MetaADEDB
Burning Sensation MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Hypertrophy MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Carotid Artery Stenosis MetaADEDB
Cerebral Disorder MetaADEDB
Cmv Infection MetaADEDB
Conjunctival Deposit MetaADEDB
Coronary Artery Stenosis MetaADEDB
Csf Protein MetaADEDB
Cystitis Noninfective MetaADEDB
Deglutition Disorder MetaADEDB
Dermatitis Psoriasiform MetaADEDB
Dermographism MetaADEDB
Device Malfunction MetaADEDB
Diabetes MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Drowsiness MetaADEDB
Dry Throat MetaADEDB
Duodenal Ulcer Perforation MetaADEDB
Ear Haemorrhage MetaADEDB
Ejection Fraction Decreased MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Eye Swelling MetaADEDB
Femoral Artery Occlusion MetaADEDB
General Physical Health Deterioration MetaADEDB
Glomerulonephritis Chronic MetaADEDB
Glucose Intolerance MetaADEDB
Granulocytosis MetaADEDB
Haemoglobin Abnormal MetaADEDB
Haemorrhage Intracranial MetaADEDB
Hepatic Trauma MetaADEDB
Hepatocellular Damage MetaADEDB
Hernia Hiatal MetaADEDB
Impaired Healing MetaADEDB
Interstitial Nephritis MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Jaw Disorder MetaADEDB
Kidney Failure MetaADEDB
Knee Operation MetaADEDB
Left Ventricular End-Diastolic Pressure Increased MetaADEDB
Livedo Reticularis MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Mastication Disorder MetaADEDB
Miosis MetaADEDB
Motor Retardation MetaADEDB
Mouth Ulcer MetaADEDB
Movement Disorder MetaADEDB
Muscle Weakness MetaADEDB
Myocardial Fibrosis MetaADEDB
Nasal Septal Operation MetaADEDB
Nasal Septum Disorder MetaADEDB
Oliguria MetaADEDB
Onycholysis MetaADEDB
Palsies MetaADEDB
Pemphigus MetaADEDB
Peripheral Arterial Occlusive Disease MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Polyuria MetaADEDB
Psychiatric Symptom MetaADEDB
Rash Generalised MetaADEDB
Retinal Bleeding MetaADEDB
Retinal Vein Occlusion MetaADEDB
Rhabdomyolysis MetaADEDB
Small Intestinal Ulcer Haemorrhage MetaADEDB
Splenitis MetaADEDB
Sudden Death MetaADEDB
Tachycardia Ventricular MetaADEDB
Transaminases Increased MetaADEDB
Ventricular Hypokinesia MetaADEDB

InAADR: Drug-Protein-ADRs database