InAADR

Drug Information

Drug Name: Isosorbide (652-67-5)
PubChem ID: 12597
SMILES: C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O)O
InchiKey: KLDXJTOLSGUMSJ-JGWLITMVSA-N
Therapeutic Category: Diuretics, Natriuretic Agents

Computed Drug Properties

Molecular Weight (dalton): 146.142
LogP: -1.4942
Ring Count: 0
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 58.92

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abnormal Gait MetaADEDB
Abnormal Vision MetaADEDB
Accommodation Disorder MetaADEDB
Acid Reflux MetaADEDB
Acne ADReCS
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Agitation ADReCS
Agoraphobia MetaADEDB
Albuminuria ADReCS
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Amaurosis ADReCS
Amaurosis Fugax ADReCS
Amentia MetaADEDB
Amnesia ADReCS
Anaemia ADReCS
Aneurysm MetaADEDB
Angina MetaADEDB
Angina Pectoris ADReCS
Angina Pectoris Aggravated ADReCS
Angina Unstable ADReCS
Anhedonia MetaADEDB
Anorectal Discomfort ADReCS
Anorexia MetaADEDB
Anticonvulsant Drug Level Above Therapeutic MetaADEDB
Anxiety ADReCS
Anxiety Disorder MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Dissection MetaADEDB
Aortic Valve Replacement MetaADEDB
Apoplexy MetaADEDB
Application Site Bruising MetaADEDB
Application Site Erythema MetaADEDB
Application Site Rash MetaADEDB
Application Site Vesicles MetaADEDB
Arrhythmia ADReCS
Arrhythmia Supraventricular ADReCS
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Arthropathy ADReCS
Asthenia ADReCS
Asystole MetaADEDB
Ataxia MetaADEDB
Atherosclerosis MetaADEDB
Atrial Fibrillation ADReCS
Atrophic Vaginitis ADReCS
Atrophic Vulvovaginitis ADReCS
Autonomic Neuropathy ADReCS
Axonal Neuropathy MetaADEDB
Back Injury MetaADEDB
Back Pain ADReCS
Bacteraemia MetaADEDB
Bacterial Infection ADReCS
Bacterial Pneumonia MetaADEDB
Biliary Colic ADReCS
Bladder Disorder MetaADEDB
Bladder Diverticulum ADReCS
Bladder Spasm MetaADEDB
Blindness ADReCS
Blindness Unilateral MetaADEDB
Blood Calcium MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Uric Acid Increased ADReCS
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bradycardia ADReCS
Brain Oedema MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Disorder Female ADReCS
Breast Pain ADReCS
Breast Pain Female ADReCS
Bronchitis ADReCS
Bronchospasm ADReCS
Bundle Branch Block ADReCS
Burning Sensation Mucosal MetaADEDB
Bursitis MetaADEDB
Calcinosis MetaADEDB
Candidiasis ADReCS
Carcinoma Of Prostate MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure ADReCS
Cardiac Fibrillation ADReCS
Cardiac Murmur ADReCS
Cardiac Pacemaker Insertion MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiovascular Disorder ADReCS
Carotid Artery Disease MetaADEDB
Carotid Artery Occlusion MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carpal Tunnel MetaADEDB
Cataract MetaADEDB
Cataract Nuclear MetaADEDB
Cerebrovascular Disorder ADReCS
Cervicalgia MetaADEDB
Chest Pain ADReCS
Chest Wall Pain MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis ADReCS
Chondrocalcinosis MetaADEDB
Chronic Fatigue Syndrome MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridium Colitis MetaADEDB
Cognitive Deterioration MetaADEDB
Cold Sweat ADReCS
Colitis Ischaemic MetaADEDB
Coma MetaADEDB
Concomitant Disease Progression MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Mitral Valve Incompetence MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Coordination Abnormal ADReCS
Coronary Artery Occlusion MetaADEDB
Coronary Artery Stenosis MetaADEDB
Cough ADReCS
Cutaneous Ulcer MetaADEDB
Dehydration MetaADEDB
Delusional Disorder Persecutory Type MetaADEDB
Dental Pain MetaADEDB
Dependence On Respirator MetaADEDB
Depressed Mood MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermatitis Psoriasiform ADReCS
Dermatosis MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus ADReCS
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes With Hyperosmolarity ADReCS
Diabetic Microangiopathy MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Difficulty In Walking MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disorientation ADReCS
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Diverticulum ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Ineffective MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dry Skin MetaADEDB
Duodenal Ulcer ADReCS
Dyspepsia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dyssomnia MetaADEDB
Dysstasia MetaADEDB
Dysuria ADReCS
Ear Pain ADReCS
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Eczema ADReCS
Ejection Fraction Decreased MetaADEDB
Electrocardiogram St-T Change MetaADEDB
Elevated Prostate Specific Antigen MetaADEDB
Emotional Distress MetaADEDB
Encephalopathy MetaADEDB
Epigastric Discomfort ADReCS
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Eructation ADReCS
Erythema MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Exfoliative Rash MetaADEDB
Extrasystoles ADReCS
Extremity Contracture MetaADEDB
Eyelid Ptosis ADReCS
Eyelid Retraction MetaADEDB
Facial Flushing MetaADEDB
Faecal Occult Blood Positive MetaADEDB
Faecaloma MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Feeling Abnormal ADReCS
Feeling Hot ADReCS
Finger Amputation MetaADEDB
Flashing Lights MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Flushing ADReCS
Gall Bladder MetaADEDB
Gamma-Glutamyltransferase Increased ADReCS
Gastric Disorder MetaADEDB
Gastric Ulcer ADReCS
Gastritis ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glossitis ADReCS
Glycosuria ADReCS
Gout ADReCS
Granulocytosis MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhage Rectum MetaADEDB
Haemorrhoids ADReCS
Hair Texture Abnormal ADReCS
Headache ADReCS
Heart Attack MetaADEDB
Heart Sounds Abnormal ADReCS
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatomegaly ADReCS
Hepatosplenomegaly MetaADEDB
Hernia MetaADEDB
Hiccups ADReCS
Hot Flush ADReCS
Hypercholesterolaemia ADReCS
Hyperhidrosis ADReCS
Hyperlipidaemia ADReCS
Hypernatraemia ADReCS
Hyperpigmentation MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hyperuricaemia ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Facial MetaADEDB
Hypocalcaemia ADReCS
Hypochromic Anaemia ADReCS
Hypoglycaemia Neonatal MetaADEDB
Hypokalaemia ADReCS
Hypokinesia ADReCS
Hypoparathyroidism MetaADEDB
Hypotension ADReCS
Hypovolaemia MetaADEDB
Ileal Ulcer MetaADEDB
Ill-Defined Disorder ADReCS
Immobile MetaADEDB
Impaired Work Ability MetaADEDB
Increased Appetite ADReCS
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Influenza ADReCS
Influenza Like Illness MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Insomnia ADReCS
Intermittent Claudication ADReCS
International Normalised Ratio Increased MetaADEDB
Intestinal Obstruction ADReCS
Intraductal Papilloma Of Breast MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Irritability ADReCS
Ischaemia ADReCS
Ischaemic Cardiomyopathy MetaADEDB
Itch MetaADEDB
Jaundice MetaADEDB
Joint Arthroplasty MetaADEDB
Joint Contracture MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Joint Sprain MetaADEDB
Large Intestinal Ulcer MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leg Amputation MetaADEDB
Lethargy ADReCS
Leukocytosis ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Ligament Sprain MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Infiltration ADReCS
Macula Lutea Degeneration MetaADEDB
Malaise ADReCS
Medication Residue MetaADEDB
Melaena ADReCS
Menopausal Symptoms ADReCS
Mental Disability ADReCS
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Methaemoglobinaemia ADReCS
Methicillin-Resistant Staphylococcal Aureus Test MetaADEDB
Microcytosis MetaADEDB
Migraine ADReCS
Mitral Valve Stenosis MetaADEDB
Movement Disorder MetaADEDB
Muscle Rupture MetaADEDB
Muscle Tightness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myelopathy MetaADEDB
Myocardial Infarction ADReCS
Myosclerosis MetaADEDB
Myositis ADReCS
Nail Tinea MetaADEDB
Nasal Congestion ADReCS
Nasal Dryness MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Neck Stiffness ADReCS
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nephrolithiasis ADReCS
Nervousness ADReCS
Neuritis ADReCS
Neuropathy Peripheral ADReCS
Nicotine Dependence MetaADEDB
Nightmare ADReCS
Nodule ADReCS
Nodule On Extremity MetaADEDB
Nuchal Rigidity ADReCS
Obstruction ADReCS
Obstructive Uropathy MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Onycholysis MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Paraesthesia ADReCS
Paresis ADReCS
Patellofemoral Pain Syndrome MetaADEDB
Periarthritis ADReCS
Peripheral Ischaemia ADReCS
Peritoneal Dialysis Complication MetaADEDB
Peritonitis Bacterial MetaADEDB
Pharyngeal Disorder ADReCS
Pharyngitis ADReCS
Pharyngolaryngeal Pain MetaADEDB
Photophobia ADReCS
Pitting Oedema MetaADEDB
Pneumonia ADReCS
Pollakiuria ADReCS
Polyuria ADReCS
Post Procedural Haematoma MetaADEDB
Presbyopia MetaADEDB
Prescribed Overdose MetaADEDB
Pressure Of Speech MetaADEDB
Procedural Pain MetaADEDB
Proctalgia ADReCS
Prostatic Disorder ADReCS
Pruritus ADReCS
Pruritus Generalised MetaADEDB
Purpura ADReCS
Rales ADReCS
Rash ADReCS
Rash Erythematous ADReCS
Reaction To Medical Agent Preservatives MetaADEDB
Rectal Tenesmus ADReCS
Renal Cyst MetaADEDB
Renal Insufficiency MetaADEDB
Respiratory Disorder ADReCS
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Rhinitis ADReCS
Scar MetaADEDB
Scleral Disorder MetaADEDB
Scrotal Haematoma MetaADEDB
Seborrhoeic Keratosis MetaADEDB
Sensory Loss MetaADEDB
Shock ADReCS
Sickle Cell Anaemia MetaADEDB
Sinus Bradycardia MetaADEDB
Sinusitis ADReCS
Skin Discolouration MetaADEDB
Skin Disorder ADReCS
Skin Fibrosis MetaADEDB
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Mass ADReCS
Skin Nodule ADReCS
Skin Plaque MetaADEDB
Skin Tightness MetaADEDB
Skin Turgor Decreased MetaADEDB
Skin Ulcer ADReCS
Somnolence ADReCS
Speech Disorder MetaADEDB
Stress Incontinence MetaADEDB
Supraventricular Tachycardia ADReCS
Surgery MetaADEDB
Syncope ADReCS
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tendon Disorder ADReCS
Tenosynovitis Stenosans MetaADEDB
Tension ADReCS
Therapeutic Response Decreased MetaADEDB
Thirst ADReCS
Thrombocytopenia ADReCS
Thyroid Disease MetaADEDB
Tinnitus ADReCS
Tongue Blistering MetaADEDB
Tooth Disorder ADReCS
Torticollis ADReCS
Transferrin Saturation Decreased MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Trigger Finger MetaADEDB
Ulcer ADReCS
Urinary Tract Infection ADReCS
Urine Output Increased ADReCS
Uterovaginal Prolapse ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Varicose Vein ADReCS
Vascular Pseudoaneurysm MetaADEDB
Vascular Purpura ADReCS
Vasospasm ADReCS
Venous Insufficiency MetaADEDB
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation MetaADEDB
Ventricular Tachycardia ADReCS
Vertigo ADReCS
Viral Infection ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Bearing Difficulty MetaADEDB
Weight Decreased ADReCS
Weight Increased ADReCS
Withdrawal Hypertension ADReCS

InAADR: Drug-Protein-ADRs database