InAADR

Drug Information

Drug Name: Isoprenaline (7683-59-2)
PubChem ID: 3779
SMILES: CC(C)NCC(C1=CC(=C(C=C1)O)O)O
InchiKey: JWZZKOKVBUJMES-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Agonists, Adrenergic beta-Agonists, Anti-Asthmatic Agents, Autonomic Agents, Bronchodilator Agents, Cardiotonic Agents, Cardiovascular Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Protective Agents, Respiratory System Agents, Sympathomimetics

Computed Drug Properties

Molecular Weight (dalton): 211.261
LogP: 1.1292
Ring Count: 1
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 72.72

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Myocardial Cell Apoptosis Dystroglycan (Q14118) Sarcolemma integrity is stabilized by the dystrophin-associated glycoprotein complex@which is disrupted in acute myocardial injury after the isoproterenol overload and related to myocardial cell apoptosis in rats [ ADR Type 1 2 ] Dystrophin disruption might be related to myocardial cell apoptosis caused by isoproterenol

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Adams-Stokes Syndrome ADReCS
Airways Obstruction ADReCS
Angina Pectoris ADReCS
Anoxia MetaADEDB
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Atrial Fibrillation MetaADEDB
Atrial Flutter MetaADEDB
Atrioventricular Block MetaADEDB
Blood Pressure Fluctuation ADReCS
Bradycardia MetaADEDB
Bronchial Diseases MetaADEDB
Cardiac Arrest ADReCS
Cardiomegaly MetaADEDB
Cardiomyopathies MetaADEDB
Cardiomyopathy Hypertrophic MetaADEDB
Central Nervous System Stimulation ADReCS
Convulsion ADReCS
Coronary Artery Insufficiency ADReCS
Death Sudden MetaADEDB
Death Sudden Cardiac MetaADEDB
Dizziness ADReCS
Dyspnoea ADReCS
Edema MetaADEDB
Fibrosis MetaADEDB
Flushing ADReCS
Headache ADReCS
Heart Arrest MetaADEDB
Heart Block MetaADEDB
Heart Diseases MetaADEDB
Heart Failure MetaADEDB
Hemorrhage MetaADEDB
Hyperalgesia MetaADEDB
Hyperemia MetaADEDB
Hyperglycemia MetaADEDB
Hyperhidrosis ADReCS
Hyperplasia MetaADEDB
Hypertension ADReCS
Hypertension Portal MetaADEDB
Hypertrophy MetaADEDB
Hypertrophy Left Ventricular MetaADEDB
Hypokalemia MetaADEDB
Hyponatremia MetaADEDB
Hypotension ADReCS
Inflammation MetaADEDB
Insomnia ADReCS
Ischemia MetaADEDB
Long Qt Syndrome MetaADEDB
Mitochondrial Diseases MetaADEDB
Mitral Valve Insufficiency MetaADEDB
Myocardial Infarction MetaADEDB
Myocardial Ischemia MetaADEDB
Myocarditis MetaADEDB
Nausea ADReCS
Necrosis MetaADEDB
Nerve Degeneration MetaADEDB
Nervousness ADReCS
Ocular Hypertension MetaADEDB
Oedema ADReCS
Pain ADReCS
Pallor ADReCS
Palpitations ADReCS
Panic Disorder MetaADEDB
Personality Disorders MetaADEDB
Pre-Excitation Syndromes MetaADEDB
Pulmonary Edema MetaADEDB
Pulmonary Oedema ADReCS
Respiratory Insufficiency MetaADEDB
Seizures MetaADEDB
Sepsis MetaADEDB
Shock Cardiogenic MetaADEDB
Sinus Arrest Cardiac MetaADEDB
Sinus Rhythm ADReCS
Status Asthmaticus MetaADEDB
Sweating MetaADEDB
Syncope MetaADEDB
Syncope Vasovagal MetaADEDB
Tachyarrhythmia ADReCS
Tachycardia ADReCS
Tachycardia Atrioventricular Nodal Reentry MetaADEDB
Tachycardia Reciprocating MetaADEDB
Tachycardia Sinus MetaADEDB
Tachycardia Supraventricular MetaADEDB
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Torsades De Pointes MetaADEDB
Tremor ADReCS
Vasospasm Intracranial MetaADEDB
Ventricular Arrhythmia ADReCS
Ventricular Dysfunction MetaADEDB
Ventricular Dysfunction Left MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Premature Complexes MetaADEDB
Ventricular Remodeling MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Vomiting MetaADEDB
Weakness MetaADEDB
Wolff-Parkinson-White Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database