InAADR

Drug Information

Drug Name: Indapamide (26807-65-8)
PubChem ID: 3702
SMILES: CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N
InchiKey: NDDAHWYSQHTHNT-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Cardiovascular Agents, Diuretics, Membrane Transport Modulators, Natriuretic Agents, Sodium Chloride Symporter Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 365.842
LogP: 2.0834
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 92.5

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Tremors Cholecystokinin octapeptide (P01356) The CCK-like peptides may play a physiological role in the regulation of extrapyramidal motor activity,which leads to tremors induced by oxotremorine, harmine and ibogaine. [ ADR Type 5 ] Zetler G Cholecystokinin octapeptide (CCK-8), ceruletide and analogues of ceruletide: effects on tremors induced by oxotremorine, harmine and ibogaine A comparison with prolyl-leucylglycine amide (MIF), anti-Parkinsonian drugs and clonazepam Neuropharmaco

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Ecg MetaADEDB
Abscess Bacterial MetaADEDB
Accommodation Disorder MetaADEDB
Acinetobacter Infection MetaADEDB
Acne ADReCS
Acute Kidney Failure MetaADEDB
Acute Tonsillitis MetaADEDB
Adhesion MetaADEDB
Adrenocortical Insufficiency Acute MetaADEDB
Aerophagia MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Albuminuria MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Allergies MetaADEDB
Alveoloplasty MetaADEDB
Amblyopia ADReCS
Amnesia ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angiitis Necrotising SIDER
Angina MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Angioimmunoblastic T-Cell Lymphoma MetaADEDB
Anhidrosis MetaADEDB
Anorexia ADReCS
Anticonvulsant Drug Level Increased MetaADEDB
Anxiety ADReCS
Aortic Valve Sclerosis MetaADEDB
Apathy MetaADEDB
Aplastic Anaemia ADReCS
Appendicitis MetaADEDB
Application Site Bruising MetaADEDB
Application Site Reaction ADReCS
Aptyalism MetaADEDB
Arrhythmia ADReCS
Arterial Disorder MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arthralgia ADReCS
Arthritis ADReCS
Arthritis Rheumatoid MetaADEDB
Arthropathy ADReCS
Asthenia ADReCS
Asthma MetaADEDB
Asthmatic Crisis MetaADEDB
Ataxia ADReCS
Atrial Fibrillation ADReCS
Atrial Flutter ADReCS
Atrioventricular Block Complete MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Azotaemia MetaADEDB
Back Pain ADReCS
Bacteria Tissue Specimen Identified MetaADEDB
Bacterial Test Positive MetaADEDB
Bad Breath MetaADEDB
Beta 2 Microglobulin Increased MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Gums MetaADEDB
Blister ADReCS
Blood Albumin Increased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Growth Hormone Increased MetaADEDB
Blood Iron Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Magnesium Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Uric Acid Increased ADReCS
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Disorder ADReCS
Bone Operation MetaADEDB
Bone Pain ADReCS
Bone Spur MetaADEDB
Bone Swelling MetaADEDB
Bone Trimming MetaADEDB
Bradycardia ADReCS
Brain Ischemia MetaADEDB
Brain Oedema MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Pain MetaADEDB
Breast Swelling MetaADEDB
Bronchiectasis MetaADEDB
Bronchitis ADReCS
Brugada Syndrome MetaADEDB
Bullous Eruption ADReCS
Bundle Branch Block ADReCS
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cancer MetaADEDB
Candida Infection MetaADEDB
Candidiasis ADReCS
Candidiasis Of Mouth MetaADEDB
Carcinoma SIDER
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Fibrillation ADReCS
Cardiac Flutter ADReCS
Cardiac Stress Test Abnormal MetaADEDB
Cardiomyopathy MetaADEDB
Cataract ADReCS
Cataract Operation MetaADEDB
Cataract Operation Complication MetaADEDB
Catheter Site Pain MetaADEDB
Catheter Site Swelling MetaADEDB
Cell Death MetaADEDB
Cerebral Ischaemia MetaADEDB
Cerebrovascular Accident ADReCS
Cervical Discharge MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholangiolitis MetaADEDB
Cholelithiasis MetaADEDB
Cholestasis Intrahepatic MetaADEDB
Chondrocalcinosis MetaADEDB
Chondrodystrophy ADReCS
Chronic Kidney Disease MetaADEDB
Colon Neoplasm MetaADEDB
Coma ADReCS
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Convulsions Grand Mal MetaADEDB
Coordination Abnormal MetaADEDB
Corneal Disorder MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Crohn Disease MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Csf Protein Increased MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deafness Bilateral MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Dental Examination MetaADEDB
Denture Wearer MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatitis Exfoliative ADReCS
Detached Retina MetaADEDB
Diabetes MetaADEDB
Diabetes Complications MetaADEDB
Diabetes Mellitus ADReCS
Diabetic Hyperosmolar Coma ADReCS
Diabetic Nephropathy MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Diplopia MetaADEDB
Discomfort ADReCS
Dislocation Of Vertebra MetaADEDB
Disorder Lung MetaADEDB
Disorder Of Globe MetaADEDB
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness SIDER
Drug Effect Delayed MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Intolerance MetaADEDB
Drug Toxicity MetaADEDB
Dry Mouth ADReCS
Duodenectomy MetaADEDB
Duodenitis ADReCS
Dysgeusia ADReCS
Dysmenorrhoea ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysuria ADReCS
Ear Ache MetaADEDB
Ear Disorder ADReCS
Ear Infection ADReCS
Ear Pain ADReCS
Eating Disorder MetaADEDB
Ecchymosis ADReCS
Eczema Infected MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Electrocardiogram Normal SIDER
Electrocardiogram U Wave Present SIDER
Electrolyte Imbalance ADReCS
Electromechanical Dissociation MetaADEDB
Embolic Cerebral Infarction MetaADEDB
Emesis MetaADEDB
Emphysema MetaADEDB
Encephalitis Allergic MetaADEDB
Enlarged Liver MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilia MetaADEDB
Epidural Lipomatosis MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction ADReCS
Eruption SIDER
Erythema ADReCS
Erythema Migrans MetaADEDB
Erythema Multiforme ADReCS
Escherichia Urinary Tract Infection MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Extrasystoles ADReCS
Extremity Pain MetaADEDB
Face Oedema ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Femoral Neck Fracture MetaADEDB
Femoral Pulse Decreased MetaADEDB
Fistula MetaADEDB
Flank Pain MetaADEDB
Flatulence ADReCS
Fluid Intake Reduced MetaADEDB
Fluid Overload MetaADEDB
Flushing ADReCS
Foetal Growth Retardation MetaADEDB
Fungal Disease MetaADEDB
Gastric Irritation SIDER
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Glasgow Coma Scale MetaADEDB
Glycosuria ADReCS
Glycosylated Haemoglobin Increased MetaADEDB
Gout ADReCS
Haematoma MetaADEDB
Haemodialysis MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Haptoglobin Decreased MetaADEDB
Headache ADReCS
Heart Rate Abnormal MetaADEDB
Heart Rate Irregular ADReCS
Helicobacter Gastritis MetaADEDB
Helicobacter Infection MetaADEDB
Hemiparesis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Fibrosis MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis B Positive MetaADEDB
Hepatobiliary Disease MetaADEDB
Hernia ADReCS
Hyaluronic Acid Increased MetaADEDB
Hyperaesthesia ADReCS
Hyperammonaemia MetaADEDB
Hypercalciuria MetaADEDB
Hypercoagulation MetaADEDB
Hyperglycaemia ADReCS
Hyperglycemia MetaADEDB
Hyperhidrosis ADReCS
Hypertension MetaADEDB
Hypertonia ADReCS
Hypertrophy Left Ventricular MetaADEDB
Hyperuricaemia ADReCS
Hypoaesthesia ADReCS
Hypochloraemia ADReCS
Hypokalaemia ADReCS
Hypokalemia MetaADEDB
Hyponatraemia ADReCS
Hyponatremia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypovolaemia MetaADEDB
Ild MetaADEDB
Ill-Defined Disorder ADReCS
Immunoglobulins Increased MetaADEDB
Impaired Healing MetaADEDB
Increased Appetite ADReCS
Increased Platelet Count MetaADEDB
Infection ADReCS
Infection Urinary Tract MetaADEDB
Influenza ADReCS
Infusion Site Mobility Decreased MetaADEDB
Injection Site Induration MetaADEDB
Injection Site Mass MetaADEDB
Injection Site Warmth MetaADEDB
Insomnia ADReCS
Intervertebral Disc Disorder MetaADEDB
Intestinal Perforation MetaADEDB
Irritability ADReCS
Ischaemic Stroke MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaw Operation MetaADEDB
Joint Injury MetaADEDB
Kidney Diseases MetaADEDB
Kidney Failure MetaADEDB
Labile Hypertension MetaADEDB
Large Intestine Perforation MetaADEDB
Laryngitis ADReCS
Lethargy ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Lightheadedness SIDER
Limb Injury MetaADEDB
Lip Ulceration MetaADEDB
Listeria Sepsis MetaADEDB
Liver Function Test Abnormal ADReCS
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Lumbar Vertebral Fracture MetaADEDB
Lung Disorder ADReCS
Lung Infiltration MetaADEDB
Macular Oedema MetaADEDB
Malaise ADReCS
Meniere Disease MetaADEDB
Menopausal Symptoms MetaADEDB
Micturition Urgency MetaADEDB
Middle Ear Effusion MetaADEDB
Migraine ADReCS
Mixed Liver Injury MetaADEDB
Mouth Ulcer MetaADEDB
Mucosal Inflammation MetaADEDB
Multiple Allergies MetaADEDB
Muscle Spasms ADReCS
Muscle Twitching ADReCS
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myasthenia SIDER
Mycobacterium Tuberculosis Infection MetaADEDB
Myopathy ADReCS
Myopia ADReCS
Nail Disorder ADReCS
Nasal Congestion MetaADEDB
Nasal Polyp MetaADEDB
Nasal Septum Deviation MetaADEDB
Nasal Turbinate Hypertrophy MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Necrolysis Epidermal SIDER
Necrosis MetaADEDB
Neoplasm Malignant ADReCS
Nephritis ADReCS
Nephritis Interstitial SIDER
Nephroangiosclerosis MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuritis ADReCS
Neuropathy Peripheral ADReCS
Nipple Pain MetaADEDB
Nocturia ADReCS
Nodule ADReCS
Non-Cardiac Chest Pain MetaADEDB
Numbness SIDER
Numbness Of Limbs SIDER
Ocular Vascular Disorder MetaADEDB
Odynophagia MetaADEDB
Oedema Peripheral ADReCS
Oesophageal Candidiasis MetaADEDB
Oesophagitis ADReCS
Oesophagitis Ulcerative MetaADEDB
Oliguria ADReCS
Optic Disc Edema MetaADEDB
Optic Ischaemic Neuropathy MetaADEDB
Optic Neuritis ADReCS
Oral Candidiasis ADReCS
Oral Fungal Infection MetaADEDB
Oral Infection MetaADEDB
Oral Surgery MetaADEDB
Orthopnea MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Osteomyelitis MetaADEDB
Osteoporosis MetaADEDB
Osteoradionecrosis MetaADEDB
Osteosclerosis MetaADEDB
Otitis SIDER
Pain ADReCS
Palpitations ADReCS
Pancreatic Insufficiency MetaADEDB
Pancreatitis ADReCS
Pancytopenia MetaADEDB
Paraesthesia ADReCS
Paraesthesia Oral SIDER
Periodontal Disease MetaADEDB
Peritonitis MetaADEDB
Petechia MetaADEDB
Pharyngitis ADReCS
Phlebothrombosis MetaADEDB
Photophobia ADReCS
Photosensitive Rash MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pleural Effusion MetaADEDB
Pneumonia ADReCS
Pneumonitis ADReCS
Pollakiuria ADReCS
Polyuria ADReCS
Poor Dental Condition MetaADEDB
Post Procedural Haematoma MetaADEDB
Post Procedural Stroke MetaADEDB
Proctitis ADReCS
Productive Cough MetaADEDB
Prostatic Disorder ADReCS
Pruritus ADReCS
Pulmonary Hypertension MetaADEDB
Purpura ADReCS
Pyrexia ADReCS
Rash ADReCS
Renal Failure ADReCS
Renal Impairment MetaADEDB
Renal Pain ADReCS
Respiratory Distress ADReCS
Respiratory Tract Congestion MetaADEDB
Retinal Tear MetaADEDB
Rhabdomyolysis ADReCS
Rhinitis ADReCS
Rhinorrhoea ADReCS
Rhonchi MetaADEDB
Salivary Gland Inflammation MetaADEDB
Scar MetaADEDB
Scleroderma Renal Crisis MetaADEDB
Scotoma MetaADEDB
Scrotal Haematoma MetaADEDB
Sensory Loss ADReCS
Serum Ferritin Increased MetaADEDB
Shock ADReCS
Sialoadenitis ADReCS
Sick Sinus Syndrome MetaADEDB
Sinus Bradycardia ADReCS
Sinus Disorder MetaADEDB
Sinusitis ADReCS
Sjogren Syndrome MetaADEDB
Skin Laceration MetaADEDB
Skin Mass ADReCS
Skin Necrosis MetaADEDB
Skin Nodule ADReCS
Sleep Disorders MetaADEDB
Small Intestine Operation MetaADEDB
Somnolence ADReCS
Spinal Column Stenosis MetaADEDB
Spinal Cord Compression MetaADEDB
Spinal Fracture MetaADEDB
Spinal Fusion Surgery MetaADEDB
Spinal Myelogram Abnormal MetaADEDB
Spinning Sensation MetaADEDB
Sputum Discoloured MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stomach Ache SIDER
Stomatitis ADReCS
Stress MetaADEDB
Subcutaneous Emphysema MetaADEDB
Subcutaneous Haematoma MetaADEDB
Subcutaneous Nodule MetaADEDB
Supraventricular Tachycardia ADReCS
Sweating SIDER
Syncope ADReCS
Tachycardia ADReCS
Temporomandibular Joint Syndrome MetaADEDB
Tension ADReCS
Thrombocytopenia ADReCS
Thyroid Disorder SIDER
Thyroiditis Subacute MetaADEDB
Tingling Mouth SIDER
Tingling Sensation SIDER
Tinnitus ADReCS
Tongue Dry MetaADEDB
Tongue Injury MetaADEDB
Tooth Disease MetaADEDB
Tooth Disorder ADReCS
Tooth Extraction MetaADEDB
Torsades De Pointes MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Transaminases Increased MetaADEDB
Transferrin Saturation Increased MetaADEDB
Treatment Noncompliance MetaADEDB
Tri-Iodothyronine Increased MetaADEDB
Tricuspid Valve Sclerosis MetaADEDB
Troponin Increased MetaADEDB
Tubulointerstitial Nephritis ADReCS
Tumour Lysis Syndrome MetaADEDB
Urethral Disorder MetaADEDB
Urinary Calculi MetaADEDB
Urinary Tract Infection ADReCS
Urinary Tract Infection Bacterial MetaADEDB
Urine Colour Abnormal MetaADEDB
Urine Flow Decreased MetaADEDB
Urine Output Increased ADReCS
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vascular Purpura ADReCS
Vascular Skin Disorder MetaADEDB
Vasculitis ADReCS
Vasculitis Necrotising ADReCS
Vasodilation SIDER
Vasodilation Procedure ADReCS
Ventricular Arrhythmia ADReCS
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vitamin B12 Increased MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Decreased ADReCS
Wound Dehiscence MetaADEDB
Wound Infection MetaADEDB
Wound Infection Staphylococcal MetaADEDB
Wound Secretion MetaADEDB
Xanthopsia ADReCS

InAADR: Drug-Protein-ADRs database