InAADR

Drug Information

Drug Name: Hydroxocobalamin (13422-51-0)
PubChem ID: 122361637
SMILES: CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(/C(=C(/C7=N/C(=CC8=N/C(=C(C4=N5)/C)/C(C8(C)C)CCC(=O)N)/C(C7(C)CC(=O)N)CCC(=O)N)C)/[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.O.Cl.[Co+2]
InchiKey: BBQILPBAMXKFOB-UHFFFAOYSA-L
Therapeutic Category: Growth Substances, Hematinics, Hematologic Agents, Micronutrients, Vitamin B Complex, Vitamins

Computed Drug Properties

Molecular Weight (dalton): 1383.84
LogP: 2.90994
Ring Count: 2
Hydrogen Bond Acceptor Count: 19
Hydrogen Bond Donor Count: 9
Total Polar Surface Area: 496.42

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain MetaADEDB
Abdominal Sepsis MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Failure MetaADEDB
Agitation ADReCS
Alveolitis Fibrosing MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylaxis MetaADEDB
Anemia Pernicious MetaADEDB
Angioedema PROTECT
Angiopathy ADReCS
Anhidrosis MetaADEDB
Anorexia MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Apoplexy MetaADEDB
Aptyalism MetaADEDB
Arteriovenous Graft Thrombosis MetaADEDB
Autoimmune Thrombocytopenia MetaADEDB
Bleb MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Pressure Decreased PROTECT
Blood Pressure Increased ADReCS
Blood Prolactin Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Brain Death MetaADEDB
Brain Oedema MetaADEDB
Bruise MetaADEDB
Burning Sensation Mucosal MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enlargement MetaADEDB
Cardiac Ventricular Disorder MetaADEDB
Cardiogenic Shock MetaADEDB
Cartilage Development Disorder MetaADEDB
Cerebral Atrophy MetaADEDB
Cheilitis MetaADEDB
Chest Discomfort ADReCS
Chest Infection MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Chromaturia ADReCS
Clostridial Infection MetaADEDB
Colon Cancer Metastatic MetaADEDB
Confabulation MetaADEDB
Constipated MetaADEDB
Coombs Indirect Test Positive MetaADEDB
Coughing Blood MetaADEDB
Deep Vein Thromboses MetaADEDB
Dehydration MetaADEDB
Dermatitis ADReCS
Device Failure MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Dislocation Of Joint Prosthesis MetaADEDB
Diverticulitis MetaADEDB
Dizziness ADReCS
Drug Hypersensitivity MetaADEDB
Dry Throat ADReCS
Duodenal Ulcer Perforation MetaADEDB
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Effusion ADReCS
Electrocardiogram Repolarisation Abnormality ADReCS
Electrolyte Disorder MetaADEDB
Embolism Pulmonary MetaADEDB
Epistaxis MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Escherichia Infection MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Extrasystoles ADReCS
Eye Disorder SIDER
Eye Irritation PROTECT
Eye Swelling PROTECT
Fatigue MetaADEDB
Fluid Imbalance MetaADEDB
Flushing ADReCS
Fractured Pelvis Nos MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Toxicity MetaADEDB
Haematochezia ADReCS
Haematological Malignancy MetaADEDB
Haematoma MetaADEDB
Head Banging MetaADEDB
Headache ADReCS
Heart Rate Increased ADReCS
Herpes Zoster MetaADEDB
Hip Surgery MetaADEDB
Hot Flush ADReCS
Hyperphosphataemia MetaADEDB
Hypersensitivity ADReCS
Hypoaesthesia Facial MetaADEDB
Ild MetaADEDB
Immune System Disorder SIDER
Incorrect Dose Administered MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Urinary Tract MetaADEDB
Influenza Like Illness MetaADEDB
Infusion Site Erythema MetaADEDB
Infusion Site Infection MetaADEDB
Infusion Site Inflammation MetaADEDB
Infusion Site Mass MetaADEDB
Infusion Site Pain MetaADEDB
Infusion Site Reaction ADReCS
Injection Site Pain ADReCS
Injection Site Reaction ADReCS
Irritability ADReCS
Kidney Infection MetaADEDB
Lip Ulceration MetaADEDB
Loss Of Weight MetaADEDB
Lung Fibrosis MetaADEDB
Lymphocyte Count Decreased ADReCS
Lymphocyte Percentage Decreased PROTECT
Mediastinal Disorder SIDER
Memory Impairment ADReCS
Menopausal Symptoms ADReCS
Mental Disorder SIDER
Mental Impairment MetaADEDB
Middle Ear Effusion MetaADEDB
Mouth Ulcer MetaADEDB
Muscle Disorder MetaADEDB
Muscle Weakness MetaADEDB
Myasthenia Gravis MetaADEDB
Nausea ADReCS
Nervous System Disorder SIDER
Neumonia MetaADEDB
Neutropenic Sepsis MetaADEDB
No Match PROTECT
Nuclear Magnetic Resonance Imaging Brain Abnormal MetaADEDB
Ocular Hyperaemia PROTECT
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Optic Neuritis MetaADEDB
Pain ADReCS
Pallor MetaADEDB
Pancreatitis MetaADEDB
Peroneal Nerve Palsy MetaADEDB
Petechia MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pruritus ADReCS
Rash ADReCS
Rash Pustular PROTECT
Redness SIDER
Restlessness ADReCS
Sensation Of Foreign Body ADReCS
Sinus Operation MetaADEDB
Sputum Abnormal MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Swelling ADReCS
Tachycardia ADReCS
Throat Tightness ADReCS
Urinary Tract Infection Bacterial MetaADEDB
Urinary Tract Infection Enterococcal MetaADEDB
Urticaria ADReCS
Vascular Access Complication MetaADEDB
Ventricular Extrasystoles ADReCS
Viith Nerve Paralysis MetaADEDB
Vision Disorders MetaADEDB
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database