| Drug Name: | Glimepiride (93479-97-1) |
|---|---|
| PubChem ID: | 3476 |
| SMILES: | CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C |
| InchiKey: | WIGIZIANZCJQQY-UHFFFAOYSA-N |
| Therapeutic Category: | Anti-Arrhythmia Agents, Cardiovascular Agents, Hypoglycemic Agents, Immunologic Factors, Immunosuppressive Agents |
| Molecular Weight (dalton) | : | 490.626 |
| LogP | : | 3.074 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 5 |
| Hydrogen Bond Donor Count | : | 3 |
| Total Polar Surface Area | : | 124.68 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Blood Sugar Lowering Effect | sulfonylurea receptors (Q09429) | Drastic decrease of the dissociation rate constant of glimepiride leads to acute blood sugar lowering efficacy. [ ADR Type 1 ] | Differential interaction of glimepiride and glibenclamide with the beta-cell sulfonylurea receptor I Binding characteristics |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| with breakfast | Absolute Bioavailability | Food-Drug Interactions |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category