InAADR

Drug Information

Drug Name: Fosphenytoin (93390-81-9)
PubChem ID: 56339
SMILES: C1=CC=C(C=C1)C2(C(=O)N(C(=O)N2)COP(=O)(O)O)C3=CC=CC=C3
InchiKey: XWLUWCNOOVRFPX-UHFFFAOYSA-N
Therapeutic Category: Anticonvulsants, Central Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 362.278
LogP: 1.5488
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 116.17

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Accidental Injury ADReCS
Accommodation Disorder MetaADEDB
Acidosis ADReCS
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenitis MetaADEDB
Affect Lability ADReCS
Ageusia ADReCS
Agitated MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agraphia MetaADEDB
Akathisia ADReCS
Albuminuria ADReCS
Alkalosis ADReCS
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Altered State Of Consciousness ADReCS
Alveolitis MetaADEDB
Amblyopia ADReCS
Ammonia Increased MetaADEDB
Amnesia ADReCS
Anaemia ADReCS
Angina MetaADEDB
Angioedema MetaADEDB
Anhedonia MetaADEDB
Anion Gap Increased MetaADEDB
Anisocytosis MetaADEDB
Anorectal Discomfort ADReCS
Anorexia ADReCS
Anoxia MetaADEDB
Anticonvulsant Drug Level Abnormal MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Anuria MetaADEDB
Anxiety MetaADEDB
Aortic Atherosclerosis MetaADEDB
Aphasia ADReCS
Apnea MetaADEDB
Apnoea ADReCS
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arthralgia ADReCS
Arthropathy MetaADEDB
Ascites MetaADEDB
Aspiration ADReCS
Asthenia ADReCS
Asthma ADReCS
Astrocytoma MetaADEDB
Asystole MetaADEDB
Ataxia ADReCS
Atelectasis ADReCS
Atherosclerosis MetaADEDB
Athetosis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Flutter ADReCS
Atrial Tachycardia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Biopsy Skin MetaADEDB
Birth Defect MetaADEDB
Bleb MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urine Present MetaADEDB
Bone Debridement MetaADEDB
Bone Disorder MetaADEDB
Bone Formation Increased MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Neoplasm Malignant MetaADEDB
Bone Pain MetaADEDB
Bone Spur MetaADEDB
Bone Trimming MetaADEDB
Bradycardia ADReCS
Bradycardia Neonatal MetaADEDB
Brain Oedema ADReCS
Breast Cancer Metastatic MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchitis ADReCS
Bruise MetaADEDB
Bulging MetaADEDB
Bundle Branch Block ADReCS
Cachexia ADReCS
Candida Infection MetaADEDB
Candidiasis ADReCS
Cardiac Arrest ADReCS
Cardiac Disease MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Flutter ADReCS
Cardiac Ischemia MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomegaly ADReCS
Cellulitis MetaADEDB
Central Venous Pressure Increased MetaADEDB
Cerebral Haemorrhage ADReCS
Cerebral Infarction ADReCS
Cervicalgia MetaADEDB
Cervix Disorder MetaADEDB
Chills ADReCS
Cholangiolitis MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Circumoral Paresthesia ADReCS
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cns Depression Nos SIDER
Coated Tongue MetaADEDB
Cognitive Deterioration MetaADEDB
Cognitive Disorder MetaADEDB
Coma ADReCS
Confabulation MetaADEDB
Confusional State ADReCS
Conjunctivitis ADReCS
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Coronary Artery Stenosis MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Cryptococcosis ADReCS
Culture Positive MetaADEDB
Culture Wound Positive MetaADEDB
Cyanosis ADReCS
Cytolytic Hepatitis MetaADEDB
Deafness ADReCS
Decreased Appetite ADReCS
Decreased Interest MetaADEDB
Deep Vein Thromboses MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration ADReCS
Delirium ADReCS
Demyelination MetaADEDB
Depersonalisation ADReCS
Depressed Level Of Consciousness ADReCS
Depression ADReCS
Dermatitis ADReCS
Dermatitis Bullous MetaADEDB
Dermatitis Contact ADReCS
Dermatitis Exfoliative MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Dermatosis MetaADEDB
Device Interaction MetaADEDB
Diabetes Insipidus ADReCS
Diabetes Mellitus ADReCS
Dialysis MetaADEDB
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drug Dispensing Error MetaADEDB
Drug Hypersensitivity MetaADEDB
Dry Mouth ADReCS
Dysarthria ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Dysuria ADReCS
Ear Ache MetaADEDB
Ear Pain ADReCS
Ecchymosis ADReCS
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Electrocardiogram Qt Prolonged ADReCS
Electrocardiogram T Wave Abnormal MetaADEDB
Embolism ADReCS
Embolus SIDER
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalitis ADReCS
Encephalopathy ADReCS
Enterococcal Infection MetaADEDB
Epilepsy MetaADEDB
Epistaxis ADReCS
Eruption MetaADEDB
Erythema Multiforme MetaADEDB
Excess Potassium MetaADEDB
Extensor Plantar Response ADReCS
Extrapyramidal Disorder ADReCS
Extrasystoles ADReCS
Eye Pain ADReCS
Face Oedema ADReCS
Facial Palsy MetaADEDB
Failure To Thrive MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Flashing Lights MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Fluid Retention ADReCS
Folliculitis MetaADEDB
Fungal Disease MetaADEDB
Gastritis ADReCS
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Sounds Abnormal MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Oedema ADReCS
Gingival Pain MetaADEDB
Glomerulosclerosis MetaADEDB
Haematoma ADReCS
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemoptysis ADReCS
Haemorrhage Subcutaneous MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hematoma Subdural MetaADEDB
Hemiparesis MetaADEDB
Hemiplegia ADReCS
Hepatic Failure MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatitis MetaADEDB
Hepatorenal Failure MetaADEDB
Hostility ADReCS
Hydrocephalus MetaADEDB
Hyperacusis ADReCS
Hyperaesthesia ADReCS
Hyperammonaemic Encephalopathy MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hyperkinesia ADReCS
Hyperphosphataemia MetaADEDB
Hyperreflexia ADReCS
Hypertension ADReCS
Hypertensive Heart Disease MetaADEDB
Hyperventilation ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Oral MetaADEDB
Hypochromasia MetaADEDB
Hypochromic Anaemia ADReCS
Hypokalaemia ADReCS
Hypokinesia ADReCS
Hypophagia MetaADEDB
Hypophosphataemia ADReCS
Hyporeflexia ADReCS
Hypotension ADReCS
Hypotonia ADReCS
Hypovolaemia MetaADEDB
Hypoxia ADReCS
Ileus ADReCS
Ill-Defined Disorder ADReCS
Immune System Disorder MetaADEDB
Impaired Healing MetaADEDB
Inborn Error Of Metabolism MetaADEDB
Incontinence ADReCS
Incorrect Dose Administered MetaADEDB
Increased Bronchial Secretion ADReCS
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Inflammation ADReCS
Influenza ADReCS
Infusion Related Reaction MetaADEDB
Infusion Site Erythema MetaADEDB
Infusion Site Infection MetaADEDB
Infusion Site Pain MetaADEDB
Infusion Site Reaction MetaADEDB
Infusion Site Swelling MetaADEDB
Injection Site Haemorrhage ADReCS
Injection Site Inflammation ADReCS
Injection Site Oedema ADReCS
Injection Site Reaction ADReCS
Insomnia ADReCS
International Normalised Ratio Increased MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intracranial Pressure Increased ADReCS
Intracranial Tumour Haemorrhage MetaADEDB
Iron Binding Capacity Total Decreased MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Ischaemic Hepatitis MetaADEDB
Itch MetaADEDB
Ketosis ADReCS
Kidney Failure MetaADEDB
Laboratory Test Interference MetaADEDB
Laceration MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Leg Cramps ADReCS
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukocytosis ADReCS
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Lichen Planus MetaADEDB
Life Expectancy Shortened MetaADEDB
Liver Function Test Abnormal ADReCS
Localised Oedema MetaADEDB
Loss Of Consciousness ADReCS
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Lyell MetaADEDB
Lymphadenopathy ADReCS
Lymphocytes Decreased MetaADEDB
Macrocytosis MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Mastication Disorder MetaADEDB
Mastoiditis MetaADEDB
Mediastinal Disorder MetaADEDB
Meningitides MetaADEDB
Meningitis ADReCS
Mental Disability ADReCS
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Acidosis MetaADEDB
Metastases To Abdominal Cavity MetaADEDB
Metastases To Skin MetaADEDB
Migraine ADReCS
Mood Swings ADReCS
Mouth Bleeding MetaADEDB
Mouth Injury MetaADEDB
Mouth Pain MetaADEDB
Mouth Ulcer MetaADEDB
Mucosal Inflammation MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Relaxant Therapy ADReCS
Muscle Spasms ADReCS
Muscle Twitching ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder MetaADEDB
Myalgia ADReCS
Myasthenia SIDER
Mydriasis ADReCS
Myoclonus ADReCS
Myopathy ADReCS
Nausea ADReCS
Neonatal Anoxia MetaADEDB
Neonatal Aspiration MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neurosis ADReCS
No Therapeutic Response MetaADEDB
Nodule ADReCS
Nystagmus ADReCS
Occult Blood Positive MetaADEDB
Oedema ADReCS
Oedema Genital ADReCS
Oedema Mouth MetaADEDB
Oliguria ADReCS
Open Wound MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Osteolysis MetaADEDB
Ovarian Cyst MetaADEDB
Overdose MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Paraesthesia ADReCS
Paraesthesia Oral ADReCS
Paralysis ADReCS
Parosmia ADReCS
Pelvic Pain ADReCS
Periarthritis MetaADEDB
Personality Disorder ADReCS
Petechia MetaADEDB
Petechiae ADReCS
Pharyngitis ADReCS
Phlebitis MetaADEDB
Photophobia ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pitting Oedema MetaADEDB
Platelet Count MetaADEDB
Platelet Toxicity MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia ADReCS
Pneumonia Aspiration ADReCS
Pneumothorax ADReCS
Polyuria ADReCS
Post Procedural Complication MetaADEDB
Post Procedural Pain MetaADEDB
Proctalgia ADReCS
Pruritus ADReCS
Psychotic Disorder ADReCS
Pulmonary Artery Dilatation MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Embolism ADReCS
Pyrexia ADReCS
Rales MetaADEDB
Rash ADReCS
Rash Generalised MetaADEDB
Rash Maculo-Papular ADReCS
Rash Pustular ADReCS
Rectal Tenesmus ADReCS
Red Blood Cell Schistocytes Present MetaADEDB
Renal Failure ADReCS
Renal Function Test Abnormal MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Failure MetaADEDB
Resuscitation MetaADEDB
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Rhinitis ADReCS
Salivary Hypersecretion ADReCS
Salivation SIDER
Scar MetaADEDB
Scotoma ADReCS
Sepsis ADReCS
Serum Ferritin Increased MetaADEDB
Serum Sickness MetaADEDB
Shock ADReCS
Sinus Bradycardia ADReCS
Sinusitis ADReCS
Skin Desquamation MetaADEDB
Skin Discolouration ADReCS
Skin Discomfort MetaADEDB
Skin Mass ADReCS
Skin Nodule ADReCS
Somnolence ADReCS
Speech Disorder ADReCS
Spleen Disorder MetaADEDB
Sputum Increased ADReCS
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stupor ADReCS
Subarachnoid Haemorrhage MetaADEDB
Subdural Haematoma ADReCS
Sweating SIDER
Swollen Tongue MetaADEDB
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Temporomandibular Joint Syndrome MetaADEDB
Tension ADReCS
Thinking Abnormal ADReCS
Thrombocytopenia ADReCS
Thrombophlebitis ADReCS
Thrombotic Microangiopathy MetaADEDB
Tingling Sensation SIDER
Tinnitus ADReCS
Tongue Disorder ADReCS
Tongue Oedema ADReCS
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Impacted MetaADEDB
Tracheostomy MetaADEDB
Tremor ADReCS
Type 2 Diabetes Mellitus ADReCS
Urethral Pain ADReCS
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Infection Pseudomonal MetaADEDB
Urine Output Increased ADReCS
Urosepsis MetaADEDB
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vaginal Moniliasis SIDER
Vasodilatation ADReCS
Vasodilation SIDER
Vasodilation Procedure ADReCS
Venous Stenosis MetaADEDB
Ventricular Extrasystoles ADReCS
Vertigo ADReCS
Visual Field Defect ADReCS
Vitamin B 12 Deficiency MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Mycotic Infection ADReCS
Wisdom Teeth Removal MetaADEDB

InAADR: Drug-Protein-ADRs database