InAADR

Drug Information

Drug Name: Febuxostat (144060-53-7)
PubChem ID: 134018
SMILES: CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O
InchiKey: BQSJTQLCZDPROO-UHFFFAOYSA-N
Therapeutic Category: Antirheumatic Agents, Gout Suppressants

Computed Drug Properties

Molecular Weight (dalton): 316.382
LogP: 3.7232
Ring Count: 2
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 83.21

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abnormal Faeces ADReCS
Acne ADReCS
Activated Partial Thromboplastin Time Prolonged ADReCS
Acute Coronary Syndrome ADReCS
Affect Lability ADReCS
Aggression ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Alopecia ADReCS
Amylase Increased SIDER
Anaemia ADReCS
Anaphylactic Reaction PROTECT
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anencephaly ADReCS
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anorexia ADReCS
Antinuclear Antibody Positive ADReCS
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy ADReCS
Aplastic Anaemia ADReCS
Arrhythmia Supraventricular ADReCS
Arthralgia ADReCS
Arthritis ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Asthma ADReCS
Ataxia ADReCS
Atrial Fibrillation ADReCS
Atrial Flutter ADReCS
Balance Disorder ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Amylase Increased ADReCS
Blood Bicarbonate Decreased ADReCS
Blood Cholesterol Increased ADReCS
Blood Creatine Increased ADReCS
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Glucose Increased ADReCS
Blood Lactate Dehydrogenase Increased ADReCS
Blood Potassium Increased ADReCS
Blood Sodium Increased ADReCS
Blood Thyroid Stimulating Hormone Increased ADReCS
Blood Triglycerides Increased ADReCS
Blood Urea Increased ADReCS
Blood Urea Nitrogen/Creatinine Ratio Increased ADReCS
Bradycardia ADReCS
Brain Oedema ADReCS
Breast Pain ADReCS
Bronchitis ADReCS
Bursitis PROTECT
Cardiac Arrest ADReCS
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Fibrillation ADReCS
Cardiac Flutter ADReCS
Cardiac Murmur ADReCS
Cardiovascular Disorder ADReCS
Cerebrovascular Accident ADReCS
Cerebrovascular Disorder ADReCS
Chest Discomfort ADReCS
Chest Pain ADReCS
Chills ADReCS
Cholecystitis ADReCS
Cholelithiasis ADReCS
Choreoathetosis ADReCS
Coagulation Test Abnormal ADReCS
Coagulopathy ADReCS
Coma ADReCS
Confusional State ADReCS
Congenital Genital Malformation ADReCS
Conjunctivitis ADReCS
Connective Tissue Disorder SIDER
Constipation ADReCS
Contusion ADReCS
Cough ADReCS
Creatine Increased SIDER
Creatinine Increased SIDER
Deafness ADReCS
Death ADReCS
Decreased Appetite ADReCS
Defaecation Urgency ADReCS
Dehydration ADReCS
Delusion ADReCS
Depression ADReCS
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Diabetes Mellitus ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Disseminated Intravascular Coagulation ADReCS
Distention SIDER
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drug Hypersensitivity PROTECT
Dry Mouth ADReCS
Dysarthria ADReCS
Dysgeusia ADReCS
Dyskinesia ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Dystonia ADReCS
Dysuria ADReCS
Ecchymosis ADReCS
Eczema ADReCS
Electrocardiogram Abnormal ADReCS
Electroencephalogram Abnormal ADReCS
Encephalocele ADReCS
Encephalopathy ADReCS
Enteritis ADReCS
Eosinophilia ADReCS
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erythema PROTECT
Erythema Multiforme ADReCS
Euphoric Mood ADReCS
Exfoliative Rash PROTECT
Extrapyramidal Disorder ADReCS
Eye Disorder SIDER
Face Oedema ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Flatulence ADReCS
Flushing ADReCS
Frequent Bowel Movements PROTECT
Gait Disturbance ADReCS
Gamma-Glutamyltransferase Increased ADReCS
Gangrene ADReCS
Gastric Dilatation ADReCS
Gastric Ph Decreased ADReCS
Gastric Ulcer ADReCS
Gastritis ADReCS
Gastrointestinal Discomfort ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gingival Bleeding ADReCS
Gingival Pain ADReCS
Glossitis ADReCS
Glucose Increased SIDER
Gout PROTECT
Granulocytopenia ADReCS
Guillain-Barre Syndrome ADReCS
Gynaecomastia ADReCS
Haematemesis ADReCS
Haematochezia ADReCS
Haematocrit Decreased ADReCS
Haematuria ADReCS
Haemoglobin Decreased ADReCS
Haemolytic Anaemia ADReCS
Haemolytic Uraemic Syndrome ADReCS
Hair Colour Changes ADReCS
Hair Growth Abnormal ADReCS
Hallucination ADReCS
Headache ADReCS
Hemianopia ADReCS
Hemiparesis ADReCS
Henoch-Schonlein Purpura ADReCS
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Steatosis ADReCS
Hepatitis ADReCS
Hepatobiliary Disease SIDER
Hepatomegaly ADReCS
Hepatorenal Syndrome ADReCS
Herpes Nos SIDER
Herpes Virus Infection ADReCS
Herpes Zoster ADReCS
Hiccups ADReCS
Hot Flush ADReCS
Hyperammonaemia ADReCS
Hyperchlorhydria ADReCS
Hypercholesterolaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperlipidaemia ADReCS
Hypernatraemia ADReCS
Hyperpyrexia ADReCS
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertriglyceridaemia ADReCS
Hypoacusis ADReCS
Hypoaesthesia ADReCS
Hypocalcaemia ADReCS
Hypochromic Anaemia ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypomagnesaemia ADReCS
Hyponatraemia ADReCS
Hypophosphataemia ADReCS
Hyposmia ADReCS
Hypotension ADReCS
Hypothermia ADReCS
Hypoxia ADReCS
Idiopathic Thrombocytopenic Purpura ADReCS
Ileus ADReCS
Immune System Disorder SIDER
Inappropriate Antidiuretic Hormone Secretion ADReCS
Incontinence ADReCS
Increased Appetite ADReCS
Infarction ADReCS
Infection ADReCS
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Influenza Like Illness ADReCS
Insomnia ADReCS
Insufficiency Renal SIDER
Intestinal Obstruction ADReCS
Intra-Uterine Death ADReCS
Irritability ADReCS
Jaundice ADReCS
Joint Stiffness ADReCS
Joint Swelling ADReCS
Lactic Dehydrogenase Activity Increased SIDER
Lacunar Infarction ADReCS
Lethargy ADReCS
Leukaemia ADReCS
Leukocytosis ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Lichen Planus ADReCS
Livedo Reticularis ADReCS
Liver Function Test Abnormal PROTECT
Localized Exfoliation SIDER
Low Density Lipoprotein Increased ADReCS
Lymphadenopathy ADReCS
Lymphocyte Count Decreased ADReCS
Lymphoma ADReCS
Lymphoproliferative Disorder ADReCS
Malaise ADReCS
Mania ADReCS
Mass ADReCS
Mcv SIDER
Mean Cell Volume ADReCS
Mean Cell Volume Abnormal ADReCS
Mechanical Urticaria ADReCS
Mediastinal Disorder ADReCS
Megacolon ADReCS
Menopausal Symptoms ADReCS
Menstrual Disorder ADReCS
Mental Disability ADReCS
Mental Disorder ADReCS
Mental Impairment ADReCS
Mental Retardation ADReCS
Metrorrhagia ADReCS
Microcephaly ADReCS
Micturition Urgency PROTECT
Migraine ADReCS
Miosis ADReCS
Mononeuritis ADReCS
Mouth Ulceration ADReCS
Muscle Contractions Involuntary ADReCS
Muscle Spasms ADReCS
Muscle Tightness ADReCS
Muscle Twitching ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myeloid Leukaemia ADReCS
Myocardial Infarction ADReCS
Nasal Dryness ADReCS
Nausea ADReCS
Neoplasm ADReCS
Nephritis ADReCS
Nephrolithiasis ADReCS
Nephrotic Syndrome ADReCS
Nervous System Disorder SIDER
Nervousness ADReCS
Neurological Symptom ADReCS
Neutropenia ADReCS
Neutrophil Count Decreased ADReCS
Nystagmus ADReCS
Oedema ADReCS
Oesophagitis ADReCS
Osteochondrosis ADReCS
Otitis Media ADReCS
Pain ADReCS
Palpitations ADReCS
Pancreatitis ADReCS
Pancytopenia ADReCS
Panic Attack ADReCS
Panic Reaction ADReCS
Paraesthesia ADReCS
Paralysis ADReCS
Paranasal Sinus Hypersecretion ADReCS
Paranoia ADReCS
Peptic Ulcer ADReCS
Peripheral Embolism ADReCS
Peripheral Ischaemia ADReCS
Personality Change ADReCS
Petechiae ADReCS
Pharyngeal Oedema ADReCS
Pharyngitis ADReCS
Phosphatase Alkaline Increased SIDER
Photosensitivity SIDER
Photosensitivity Allergic Reaction ADReCS
Photosensitivity Reaction ADReCS
Pigmentation SIDER
Pigmentation Disorder ADReCS
Placental Disorder ADReCS
Platelet Count Decreased ADReCS
Platelet Function Test Abnormal ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Pneumonitis ADReCS
Pollakiuria ADReCS
Potassium Increased SIDER
Prostatic Specific Antigen Increased ADReCS
Protein Urine Present ADReCS
Proteinuria ADReCS
Prothrombin Level Increased ADReCS
Prothrombin Time Abnormal ADReCS
Prothrombin Time Prolonged ADReCS
Pruritus ADReCS
Psychotic Behaviour ADReCS
Psychotic Disorder ADReCS
Ptt Prolonged SIDER
Pulmonary Haemorrhage ADReCS
Purpura ADReCS
Pyrexia ADReCS
Rash ADReCS
Rash Erythematous PROTECT
Rash Follicular PROTECT
Rash Generalised ADReCS
Rash Macular PROTECT
Rash Maculo-Papular PROTECT
Rash Morbilliform PROTECT
Rash Papular PROTECT
Rash Pruritic PROTECT
Rash Pustular PROTECT
Rash Vesicular PROTECT
Rectal Haemorrhage ADReCS
Red Blood Cell Count Decreased ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment ADReCS
Respiratory Depression ADReCS
Respiratory Failure ADReCS
Respiratory Tract Congestion ADReCS
Respiratory Tract Infection ADReCS
Rhabdomyolysis ADReCS
Rhinitis ADReCS
Sepsis ADReCS
Sinus Bradycardia ADReCS
Sinusitis ADReCS
Skin Discolouration ADReCS
Skin Disorder ADReCS
Skin Exfoliation ADReCS
Skin Lesion ADReCS
Skin Odour Abnormal ADReCS
Smear Buccal Abnormal ADReCS
Sneezing ADReCS
Sodium High SIDER
Somnolence ADReCS
Splenomegaly ADReCS
Status Epilepticus ADReCS
Stevens-Johnson Syndrome ADReCS
Stiffness SIDER
Stomatitis ADReCS
Stroke ADReCS
Stupor ADReCS
Sudden Death ADReCS
Sudden Infant Death Syndrome ADReCS
Suicide Attempt ADReCS
Supraventricular Tachycardia ADReCS
Swelling ADReCS
Systemic Lupus Erythematosus ADReCS
Tachycardia ADReCS
Taste Altered SIDER
Tension ADReCS
Thinking Abnormal ADReCS
Thirst ADReCS
Throat Irritation ADReCS
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thrombophlebitis ADReCS
Thyrotropin High SIDER
Tinnitus ADReCS
Torsade De Pointes ADReCS
Toxic Epidermal Necrolysis ADReCS
Transient Ischaemic Attack ADReCS
Tremor ADReCS
Tubulointerstitial Nephritis ADReCS
Ulcer ADReCS
Upper Respiratory Tract Infection ADReCS
Urea Increased SIDER
Urethral Disorder SIDER
Urinary Casts ADReCS
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urine Output ADReCS
Urine Output Decreased ADReCS
Urine Output Increased ADReCS
Urticaria ADReCS
Urticaria Physical SIDER
Vaginal Haemorrhage ADReCS
Vascular Purpura ADReCS
Vertigo ADReCS
Vision Blurred ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Abnormal ADReCS
Weight Decreased ADReCS
Weight Increased ADReCS
White Blood Cell Count Decreased PROTECT
White Blood Cell Count Increased ADReCS
White Blood Cell Disorder ADReCS

InAADR: Drug-Protein-ADRs database