InAADR

Drug Information

Drug Name: Ethionamide (536-33-4)
PubChem ID: 2761171
SMILES: CCC1=NC=CC(=C1)C(=S)N
InchiKey: AEOCXXJPGCBFJA-UHFFFAOYSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents, Antimetabolites, Antitubercular Agents, Fatty Acid Synthesis Inhibitors, Hypolipidemic Agents

Computed Drug Properties

Molecular Weight (dalton): 166.249
LogP: 1.2782
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 38.91

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Isoniazid (54-85-3) Acute Psychotic Reaction Additive Not understood Toxic psychosis to isoniazid and ethionamide in a patient with pulmonary tuberculosis
Cycloserine (68-41-7) Neurotoxicity Additive Not known Reversible pellagra-like encephalopathy with ethionamide and cycloserine

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Acne ADReCS
Agitation ADReCS
Alanine Aminotransferase Increased ADReCS
Anorexia ADReCS
Aspartate Aminotransferase Increased ADReCS
Blood Bilirubin Increased ADReCS
Brain Diseases MetaADEDB
Decreased Appetite ADReCS
Depression ADReCS
Dermatitis ADReCS
Diabetes Mellitus ADReCS
Diarrhoea ADReCS
Diplopia ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug-Induced Liver Injury MetaADEDB
Dysgeusia ADReCS
Erectile Dysfunction ADReCS
Fatty Liver MetaADEDB
Gastrointestinal Diseases MetaADEDB
Gastrointestinal Disturbance ADReCS
Gastrointestinal Pain ADReCS
Gynaecomastia ADReCS
Headache ADReCS
Hepatitis ADReCS
Hypersensitivity ADReCS
Hypoglycaemia ADReCS
Hypotension ADReCS
Hypothyroidism ADReCS
Impotence ADReCS
Inappropriate Adh Syndrome MetaADEDB
Jaundice ADReCS
Leprosy Lepromatous MetaADEDB
Mental Disorders MetaADEDB
Nausea ADReCS
Neuritis ADReCS
Neuropathy Peripheral ADReCS
Nicotinic Acid Deficiency ADReCS
Optic Neuritis ADReCS
Orthostatic Hypotension ADReCS
Pain ADReCS
Peripheral Neuritis ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Psychotic Disorder ADReCS
Purpura ADReCS
Rash ADReCS
Reflex Sympathetic Dystrophy MetaADEDB
Restlessness ADReCS
Salivary Hypersecretion ADReCS
Salivation SIDER
Somnolence ADReCS
Stomatitis ADReCS
Taste Metallic ADReCS
Thrombocytopenia ADReCS
Tuberculosis MetaADEDB
Tuberculosis Multidrug-Resistant MetaADEDB
Vascular Purpura ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Weight Decreased ADReCS

InAADR: Drug-Protein-ADRs database