InAADR

Drug Information

Drug Name: Ethambutol (74-55-5)
PubChem ID: 14052
SMILES: CC[C@@H](CO)NCCN[C@@H](CC)CO
InchiKey: AEUTYOVWOVBAKS-UWVGGRQHSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents, Antitubercular Agents

Computed Drug Properties

Molecular Weight (dalton): 204.314
LogP: -0.2926
Ring Count: 0
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 64.52

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Isoniazid (54-85-3) Optic Neuropathy Synergistic Not understood Serum concentration of isoniazid administered with & without ethambutol in pulmonary tuberculosis patients

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abscess MetaADEDB
Accommodation Disorder MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Fast Bacilli Infection MetaADEDB
Acid Fast Stain Positive MetaADEDB
Acidosis MetaADEDB
Acquired Immune Deficiency Syndrome MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Psychosis MetaADEDB
Adenitis MetaADEDB
Adenopathy MetaADEDB
Adrenal Suppression MetaADEDB
Adrenocortical Insufficiency Acute MetaADEDB
Agranulocytoses MetaADEDB
Aids Encephalopathy MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Amblyopia MetaADEDB
Anaemia MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anaphylaxis MetaADEDB
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Anisocoria MetaADEDB
Anogenital Warts MetaADEDB
Anorectal Disorder MetaADEDB
Anorexia ADReCS
Antinuclear Antibody MetaADEDB
Antipsychotic Drug Level Increased MetaADEDB
Anuria MetaADEDB
Apraxia MetaADEDB
Areflexia MetaADEDB
Arterial Bypass Operation MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthralgia ADReCS
Arthritis Fungal MetaADEDB
Ascites MetaADEDB
Aseptic Meningitis MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrial Tachycardia MetaADEDB
Atypical Mycobacterial Infection MetaADEDB
Atypical Mycobacterial Lymphadenitis MetaADEDB
Bacteria Stool Identified MetaADEDB
Bacteria Urine MetaADEDB
Bacterial Vaginitis MetaADEDB
Bile Duct Obstruction MetaADEDB
Bk Virus Infection MetaADEDB
Bladder Distension MetaADEDB
Bladder Operation MetaADEDB
Bladder Perforation MetaADEDB
Blindness ADReCS
Blindness Unilateral MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Electrolytes Abnormal MetaADEDB
Blood Immunoglobulin A Increased MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Systolic Inspiratory Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Uric Acid Increased ADReCS
Blood Viscosity Increased MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Disorder MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Transplant MetaADEDB
Bovine Tuberculosis MetaADEDB
Brain Abscess MetaADEDB
Brain Stem Syndrome MetaADEDB
Breast Cyst MetaADEDB
Breast Lump Removal MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchial Disorder MetaADEDB
Bronchiectasis MetaADEDB
Cachectic MetaADEDB
Calculus Urinary MetaADEDB
Candida Infection MetaADEDB
Candidiasis Of Mouth MetaADEDB
Capillary Disorder MetaADEDB
Carbohydrate Antigen 125 Increased MetaADEDB
Cardiac Tamponade MetaADEDB
Cataplexy MetaADEDB
Cataract Nuclear MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cd4 Lymphocytes Increased MetaADEDB
Cell Death MetaADEDB
Central Nervous System Lesion MetaADEDB
Central Nervous System Lymphoma MetaADEDB
Central-Alveolar Hypoventilation MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Aspergillosis MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Toxoplasmosis MetaADEDB
Cervical Discharge MetaADEDB
Cervical Gland Tuberculosis MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Cholecystitis Acute MetaADEDB
Cholestatic Liver Injury MetaADEDB
Chorioretinitis MetaADEDB
Cirrhosis MetaADEDB
Clostridial Infection MetaADEDB
Cluster Headache MetaADEDB
Cmv Infection MetaADEDB
Colitis MetaADEDB
Color Vision Defects MetaADEDB
Colour Blindness ADReCS
Coma MetaADEDB
Complement Factor C3 Increased MetaADEDB
Complex Partial Seizures MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Contact Dermatitis MetaADEDB
Convulsion MetaADEDB
Convulsions Grand Mal MetaADEDB
Coombs Positive Haemolytic Anaemia MetaADEDB
Cor Pulmonale Acute MetaADEDB
Cough MetaADEDB
Crackles Lung MetaADEDB
Creatinine Renal Clearance Decreased MetaADEDB
Cryptococcosis MetaADEDB
Csf Pressure Increased MetaADEDB
Culture Positive MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Dandy-Walker Syndrome MetaADEDB
Deafness Congenital MetaADEDB
Deafness Neurosensory MetaADEDB
Death ADReCS
Decreased Appetite ADReCS
Delusion Of Grandeur MetaADEDB
Demyelination MetaADEDB
Dermatitis ADReCS
Dermatitis Allergic ADReCS
Dermatitis Exfoliative ADReCS
Dermatitis Psoriasiform MetaADEDB
Discomfort ADReCS
Disease Recurrence MetaADEDB
Disorder Lung MetaADEDB
Disorder Of Globe MetaADEDB
Disorientation ADReCS
Disseminated Cytomegaloviral Infection MetaADEDB
Disseminated Tuberculosis MetaADEDB
Distractibility MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drug Eruptions MetaADEDB
Drug Half-Life Increased MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Drug Rash With Eosinophilia And Systemic Symptoms ADReCS
Drug Resistance MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Duodenitis MetaADEDB
Dysaesthesia MetaADEDB
Edema MetaADEDB
Electrocardiogram Q Wave Abnormal MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Electrolyte Disorder MetaADEDB
Emesis MetaADEDB
Emotional Distress ADReCS
Emphysema MetaADEDB
Encephalitis MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalitis Cytomegalovirus MetaADEDB
Encephalopathy Hypertensive MetaADEDB
End Stage Aids MetaADEDB
Enlarged Liver MetaADEDB
Enlarged Spleen MetaADEDB
Eosinophil Count Decreased MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilia ADReCS
Eosinophilic Pneumonia MetaADEDB
Erosive Oesophagitis MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Exanthema MetaADEDB
External Ear Infection MetaADEDB
Extrapulmonary Tuberculosis MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Diseases MetaADEDB
Fanconi Syndrome MetaADEDB
Feeling Abnormal ADReCS
Fever MetaADEDB
Foetal Heart Rate Abnormal MetaADEDB
Gall Bladder MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastroduodenal Ulcer MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Tract Irritation ADReCS
General Physical Condition MetaADEDB
General Physical Health Deterioration MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Proliferative MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Glucose-6-Phosphate Dehydrogenase Deficiency MetaADEDB
Glycosuria MetaADEDB
Gout ADReCS
Gout Acute ADReCS
Granuloma MetaADEDB
Granulomatous Liver Disease MetaADEDB
Haemangioma Of Liver MetaADEDB
Haemosiderosis MetaADEDB
Hallucination ADReCS
Haptoglobin MetaADEDB
Headache ADReCS
Hematoma Subdural MetaADEDB
Hemolysis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Artery Thrombosis MetaADEDB
Hepatic Atrophy MetaADEDB
Hepatic Encephalopathy MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Abnormal MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Fibrosis MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis ADReCS
Hepatitis B MetaADEDB
Hepatitis B Surface Antigen Positive MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatocellular Injury MetaADEDB
Hepatosplenomegaly MetaADEDB
Hepatotoxicity ADReCS
Hereditary Optic Atrophy MetaADEDB
Herpes Ophthalmic MetaADEDB
Herpes Simplex MetaADEDB
Herpes Zoster MetaADEDB
Herxheimer Reaction MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hiv Disease MetaADEDB
Hiv Wasting Syndrome MetaADEDB
Hodgkin Disease MetaADEDB
Hospice Care MetaADEDB
Hydrocephalus MetaADEDB
Hyperlipaemia MetaADEDB
Hypersensitive Syndrome SIDER
Hypersensitivity ADReCS
Hypertensive Heart Disease MetaADEDB
Hypoaesthesia ADReCS
Hypoalbuminaemia MetaADEDB
Hypothyroid MetaADEDB
Hypovolaemic Shock MetaADEDB
Ill-Defined Disorder ADReCS
Immune Reconstitution Syndrome MetaADEDB
Impaired Gastric Emptying MetaADEDB
Interstitial Nephritis MetaADEDB
Intraocular Inflammation MetaADEDB
Iridocele MetaADEDB
Iridocyclitis MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Jaundice MetaADEDB
Jaundice Obstructive MetaADEDB
Kaposi Sarcoma MetaADEDB
Kidney Enlargement MetaADEDB
Kidney Fibrosis MetaADEDB
Klebsiella Sepsis MetaADEDB
Kyphosis MetaADEDB
Laparotomy MetaADEDB
Large Intestine Perforation MetaADEDB
Legionella MetaADEDB
Leucopenia MetaADEDB
Leukocyturia MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Limb Discomfort MetaADEDB
Liver Diseases MetaADEDB
Liver Transplant MetaADEDB
Loss Of Weight MetaADEDB
Lower Respiratory Tract Infection Bacterial MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration ADReCS
Lung Neoplasm MetaADEDB
Lymphadenectomy MetaADEDB
Lymphadenopathy ADReCS
Lymphatic Diseases MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Lymphoma MetaADEDB
Malaise ADReCS
Malaria MetaADEDB
Malnourished MetaADEDB
Markedly Reduced Dietary Intake MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Meningitis Tuberculous MetaADEDB
Mental Retardation MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Encephalopathy MetaADEDB
Microsporidia Infection MetaADEDB
Mitochondrial Toxicity MetaADEDB
Mixed Liver Injury MetaADEDB
Mononeuritis MetaADEDB
Mouth Ulcer MetaADEDB
Mucous Membrane Disorder MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple-Drug Resistance MetaADEDB
Muscle Abscess MetaADEDB
Muscle Necrosis MetaADEDB
Musculoskeletal Discomfort ADReCS
Mycobacterial Infection MetaADEDB
Mycobacterium Abscessus Infection MetaADEDB
Mycobacterium Avium Complex Immune Restoration Disease MetaADEDB
Mycobacterium Avium Complex Infection MetaADEDB
Mycobacterium Infections MetaADEDB
Mycobacterium Infections Nontuberculous MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myelitis MetaADEDB
Myocarditis ADReCS
Myoclonus ADReCS
Myopathy Toxic MetaADEDB
Nausea ADReCS
Necrotising Granulomatous Lymphadenitis MetaADEDB
Nephritis ADReCS
Nephropathy Toxic MetaADEDB
Nephrotic Syndrome MetaADEDB
Nerve Degeneration MetaADEDB
Nervous System Diseases MetaADEDB
Neuritis ADReCS
Neuritis Retrobulbar SIDER
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
No Therapeutic Response MetaADEDB
Nocardiosis MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Numbness SIDER
Nutritional Condition Abnormal MetaADEDB
Ocular Icterus MetaADEDB
Odynophagia MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oliguria MetaADEDB
Optic Atrophy MetaADEDB
Optic Atrophy Autosomal Dominant MetaADEDB
Optic Atrophy Hereditary Leber MetaADEDB
Optic Nerve Diseases MetaADEDB
Optic Nerve Disorder ADReCS
Optic Neuritis ADReCS
Orthopnea MetaADEDB
Ototoxicity MetaADEDB
Pain ADReCS
Pallor MetaADEDB
Paradoxical Drug Reaction MetaADEDB
Paraesthesia ADReCS
Paraparesis MetaADEDB
Parapharyngeal Abscess MetaADEDB
Pelvic Peritoneal Adhesions MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Rub MetaADEDB
Pericarditis ADReCS
Pericarditis Tuberculous MetaADEDB
Peripheral Nervous System Diseases MetaADEDB
Peripheral Neuritis ADReCS
Peripheral Sensory Neuropathy MetaADEDB
Peritoneal Tuberculosis MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phlebitis MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pneumatosis MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia ADReCS
Pneumonitis ADReCS
Polymyalgia Rheumatica MetaADEDB
Polymyositis MetaADEDB
Prealbumin Decreased MetaADEDB
Pregnancy On Oral Contraceptive MetaADEDB
Productive Cough MetaADEDB
Protein Total Increased MetaADEDB
Proteinuria MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Psychoses Substance-Induced MetaADEDB
Pubic Pain MetaADEDB
Pulmonary Calcification MetaADEDB
Pulmonary Cavitation MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Thrombosis MetaADEDB
Purulence MetaADEDB
Pyopneumothorax MetaADEDB
Pyrexia ADReCS
Radiotherapy MetaADEDB
Rash ADReCS
Refraction Disorder ADReCS
Renal Impairment MetaADEDB
Renal Insufficiency MetaADEDB
Renal Tubular Acidosis MetaADEDB
Renal Tubular Disorder MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Rate Increased MetaADEDB
Respiratory Tract Infections MetaADEDB
Retinal Diseases MetaADEDB
Retinal Pigment Epitheliopathy MetaADEDB
Retinitis MetaADEDB
Scar MetaADEDB
Scotoma ADReCS
Sensory Loss ADReCS
Sepsis Syndrome MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock Haemorrhagic MetaADEDB
Shock Septic MetaADEDB
Skin Discomfort MetaADEDB
Skin Lesion MetaADEDB
Sputum Culture Positive MetaADEDB
Sputum Discoloured MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subileus MetaADEDB
Sudden Death MetaADEDB
Thrombocytopenia ADReCS
Thrombosis In Device MetaADEDB
Tingling Sensation SIDER
Toe Deformity MetaADEDB
Tonsillectomy MetaADEDB
Tonsillitis MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Skin Eruption MetaADEDB
Toxoplasmosis MetaADEDB
Transaminases Increased MetaADEDB
Transmission Of Drug Via Semen MetaADEDB
Tuberculoid Leprosy MetaADEDB
Tuberculoma Of Central Nervous System MetaADEDB
Tuberculosis MetaADEDB
Tuberculosis Central Nervous System MetaADEDB
Tuberculosis Gastrointestinal MetaADEDB
Tuberculosis Liver MetaADEDB
Tuberculosis Lymph Node MetaADEDB
Tuberculosis Miliary MetaADEDB
Tuberculosis Multidrug-Resistant MetaADEDB
Tuberculosis Osteoarticular MetaADEDB
Tuberculosis Pleural MetaADEDB
Tuberculosis Pulmonary MetaADEDB
Tuberculosis Spinal MetaADEDB
Ultrasound Abdomen Abnormal MetaADEDB
Unintended Pregnancy MetaADEDB
Urine Odour Abnormal MetaADEDB
Vascular Pseudoaneurysm MetaADEDB
Venous Pressure Jugular Increased MetaADEDB
Vision Blurred ADReCS
Vision Disorders MetaADEDB
Visual Acuity Reduced ADReCS
Visual Acuity Tests Abnormal ADReCS
Visual Disturbance MetaADEDB
Visual Impairment ADReCS
Vith Nerve Disorder MetaADEDB
Vomiting ADReCS
Whipple Disease MetaADEDB
Wound Secretion MetaADEDB
X-Ray Limb MetaADEDB
Xanthopsia MetaADEDB

InAADR: Drug-Protein-ADRs database