| Drug Name: | Doxycycline (564-25-0) |
|---|---|
| PubChem ID: | 54671203 |
| SMILES: | C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O |
| InchiKey: | SGKRLCUYIXIAHR-AKNGSSGZSA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents, Antimalarials, Antiparasitic Agents, Antiprotozoal Agents |
| Molecular Weight (dalton) | : | 444.44 |
| LogP | : | -0.5042 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 9 |
| Hydrogen Bond Donor Count | : | 6 |
| Total Polar Surface Area | : | 181.62 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Methotrexate (59-05-2) | Diarrhoea | Synergistic | Displacement of the methotrexate from its binding sites | High-dose methotrexate-doxycycline interaction |
| Methotrexate (59-05-2) | Ulcerative Stomatitis | Synergistic | Displacement of the methotrexate from its binding sites | High-dose methotrexate-doxycycline interaction |
| dihydroergotamine (6190-39-2) | Ergotism | Synergistic | Unknown | Systemic arterial spasms Ergotamine tartrate |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category