Drug Name: | Domperidone (57808-66-9) |
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PubChem ID: | 3151 |
SMILES: | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
InchiKey: | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
Therapeutic Category: | Antiemetics, Autonomic Agents, Central Nervous System Agents, Dopamine Agents, Dopamine Antagonists, Gastrointestinal Agents, Neurotransmitter Agents, Peripheral Nervous System Agents |
Molecular Weight (dalton) | : | 425.92 |
LogP | : | 3.3532 |
Ring Count | : | 4 |
Hydrogen Bond Acceptor Count | : | 5 |
Hydrogen Bond Donor Count | : | 2 |
Total Polar Surface Area | : | 78.82 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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Cardiac Arrhythmias | Potassium voltage-gated channel subfamily H member 2 (Q12809) | Role of systems pharmacology in understanding drug adverse events | |
Somnolence | Neuropeptide S receptor (Q6W5P4) | Not Available | Large-scale prediction and testing of drug activity on side-effect targets |
This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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Grapefruit Juice | Torsade De Pointes | Grapefruit-medication interactions: forbidden fruit or avoidable consequences? |
This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category