InAADR

Drug Information

Drug Name: Domperidone (57808-66-9)
PubChem ID: 3151
SMILES: C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
InchiKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N
Therapeutic Category: Antiemetics, Autonomic Agents, Central Nervous System Agents, Dopamine Agents, Dopamine Antagonists, Gastrointestinal Agents, Neurotransmitter Agents, Peripheral Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 425.92
LogP: 3.3532
Ring Count: 4
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 78.82

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Torsade De Pointes Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp SIDER
Abdominal Pain ADReCS
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abnormal Vision MetaADEDB
Acid Fast Bacilli Infection MetaADEDB
Actinomycosis MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Prerenal Failure MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Failure MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Agitated MetaADEDB
Agraphia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alveolitis MetaADEDB
Ammonia Increased MetaADEDB
Anaemia MetaADEDB
Anal Abscess MetaADEDB
Anal Fissure MetaADEDB
Anal Haemorrhage MetaADEDB
Angina MetaADEDB
Anorexia MetaADEDB
Anti-Erythropoietin Antibody Positive MetaADEDB
Apathy MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Areflexia MetaADEDB
Arterial Disorder MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arteriovenous Fistula Site Haemorrhage MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Aspiration Bronchial MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asthmatic Crisis MetaADEDB
Attempted Suicide MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Aura MetaADEDB
Back Ache MetaADEDB
Bacterial Toxaemia MetaADEDB
Basal Ganglia Diseases MetaADEDB
Benign Colonic Neoplasm MetaADEDB
Bile Duct Obstruction MetaADEDB
Bladder Inflammation MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Unconjugated Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol Abnormal MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Sodium Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Fracture MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Pain MetaADEDB
Bradycardia MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Enlargement ADReCS
Breast Pain ADReCS
Breath Sounds MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchiolitis MetaADEDB
Bronchitis MetaADEDB
Bronchopneumonia MetaADEDB
Burn Oesophageal MetaADEDB
Campylobacter Gastroenteritis MetaADEDB
Candida Sepsis MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiogenic Shock MetaADEDB
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Cd4 Lymphocytes Decreased MetaADEDB
Cellulitis Staphylococcal MetaADEDB
Central Nervous System Diseases MetaADEDB
Chest Infection MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Choking Sensation MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Clostridium Colitis MetaADEDB
Coagulation Time Prolonged MetaADEDB
Coma MetaADEDB
Concomitant Disease Progression MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Continuous Positive Airway Pressure MetaADEDB
Convulsions Grand Mal MetaADEDB
Cough MetaADEDB
Crackles Lung MetaADEDB
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Creatinine Renal Clearance Decreased MetaADEDB
Crohn Disease MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cyanosis MetaADEDB
Cytomegalovirus Enterocolitis MetaADEDB
Death ADReCS
Death Sudden Cardiac MetaADEDB
Decreased Activity MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Developmental Delay MetaADEDB
Device Related Infection MetaADEDB
Diabetes MetaADEDB
Diarrhoea ADReCS
Disease Of Liver MetaADEDB
Disorder Lung MetaADEDB
Disorder Renal MetaADEDB
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Abuser MetaADEDB
Drug Interaction MetaADEDB
Drug Intolerance ADReCS
Drug Withdrawal MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Dyslalia MetaADEDB
Dysmenorrhea MetaADEDB
Dyspepsia ADReCS
Dysphoria MetaADEDB
Dystonia ADReCS
Dystonic Reaction SIDER
Dysuria ADReCS
Ear Ache MetaADEDB
Ear Infection MetaADEDB
Eastern Cooperative Oncology Group Performance Status Worsened MetaADEDB
Eczema MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Enteritis Infectious MetaADEDB
Enterococcal Infection MetaADEDB
Eosinophil Count Increased MetaADEDB
Epilepsy Tonic-Clonic MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Extrasystoles MetaADEDB
Faecaloma MetaADEDB
Fever MetaADEDB
Flu MetaADEDB
Flushing ADReCS
Foreign Body Aspiration MetaADEDB
Galactorrhea MetaADEDB
Galactorrhoea ADReCS
Gallbladder Operation MetaADEDB
Gamma-Glutamyltransferase MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Ulcer MetaADEDB
Gastroenteritis MetaADEDB
Gastroesophageal Reflux MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Perforation MetaADEDB
Gastroparesis MetaADEDB
Gastrostomy Tube Insertion MetaADEDB
Glasgow Coma Scale MetaADEDB
Gynaecomastia ADReCS
Gynecomastia MetaADEDB
Haematochezia MetaADEDB
Haematoma MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhoid Operation MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heartburn ADReCS
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatosplenomegaly MetaADEDB
Herpes Simplex Serology Positive MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hot Flush ADReCS
Human Herpesvirus 6 Infection MetaADEDB
Hyperparathyroidism Secondary MetaADEDB
Hyperprolactinemia MetaADEDB
Hyperreflexia MetaADEDB
Hypertension MetaADEDB
Hypertrophy ADReCS
Hyperventilation MetaADEDB
Hypoglycaemic Unconsciousness MetaADEDB
Hypokalaemia MetaADEDB
Hypophagia MetaADEDB
Hypotension MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypovolaemia MetaADEDB
Hypovolaemic Shock MetaADEDB
Ild MetaADEDB
Ileal Perforation MetaADEDB
Increased Bronchial Secretion MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Injection Site Induration MetaADEDB
Insomnia ADReCS
Intestinal Functional Disorder MetaADEDB
Intestinal Perforation MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Irregular Menstrual Cycle MetaADEDB
Irritability ADReCS
Itch MetaADEDB
Kidney Transplant Rejection MetaADEDB
Large Intestine Perforation MetaADEDB
Leg Cramps ADReCS
Lethargy ADReCS
Leukopenia Neonatal MetaADEDB
Long Qt Syndrome MetaADEDB
Lung Consolidation MetaADEDB
Lung Infection MetaADEDB
Lung Transplant MetaADEDB
Lymphangiopathy MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Mediastinal Disorder MetaADEDB
Mediastinitis MetaADEDB
Menopausal Disorder MetaADEDB
Menopausal Symptoms ADReCS
Menstruation Irregular ADReCS
Mental Impairment MetaADEDB
Metastases To Liver MetaADEDB
Metastatic Renal Cell Carcinoma MetaADEDB
Microangiopathic Haemolytic Anaemia MetaADEDB
Migraine Disorders MetaADEDB
Movement Disorders MetaADEDB
Mucosal Inflammation MetaADEDB
Muscle Enzyme MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Spasms ADReCS
Musculoskeletal Stiffness MetaADEDB
Myasthenia Gravis Crisis MetaADEDB
Myelodysplasia MetaADEDB
Nasopharyngitis MetaADEDB
Nausea MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuroendocrine Tumour MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neuromuscular Disorder MetaADEDB
Neutropenic Sepsis MetaADEDB
Nystagmus MetaADEDB
Ocular Motility Disorders MetaADEDB
Oculogyric Crisis MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oedema ADReCS
Optic Disc Disorder MetaADEDB
Optic Nerve Disorder MetaADEDB
Oral Mucosa Erosion MetaADEDB
Overdose MetaADEDB
Oxygen Supplementation MetaADEDB
Packed Red Blood Cell Transfusion MetaADEDB
Pain MetaADEDB
Pallor MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Pancreatic Abscess MetaADEDB
Pancreatic Necrosis MetaADEDB
Pancreatitis Chronic MetaADEDB
Parkinson MetaADEDB
Parkinson Disease MetaADEDB
Paroxysmal Arrhythmia MetaADEDB
Peritonitis MetaADEDB
Persecutory Delusion MetaADEDB
Pharyngeal Erythema MetaADEDB
Pharyngeal Inflammation MetaADEDB
Pharyngeal Lesion MetaADEDB
Phlebothrombosis MetaADEDB
Pica MetaADEDB
Pituitary Neoplasms MetaADEDB
Platelet Count MetaADEDB
Pollakiuria ADReCS
Polyp MetaADEDB
Procedural Pain MetaADEDB
Proctalgia MetaADEDB
Proctitis MetaADEDB
Prostatitis MetaADEDB
Prostatomegaly MetaADEDB
Pruritus ADReCS
Psoriasis MetaADEDB
Pulmonary Arrest MetaADEDB
Pupil Disorders MetaADEDB
Pyelonephritis Acute MetaADEDB
Rash ADReCS
Rash Generalised MetaADEDB
Rectal Polyp MetaADEDB
Rectal Polypectomy MetaADEDB
Regurgitation ADReCS
Renal Impairment MetaADEDB
Renal Tubular Acidosis MetaADEDB
Respiratory Syncytial Virus Infection MetaADEDB
Reticulocyte Count Increased MetaADEDB
Reticulocytosis MetaADEDB
Rhinorrhea MetaADEDB
Sclerosing Encapsulating Peritonitis MetaADEDB
Serum Ferritin Increased MetaADEDB
Sexual Dysfunctions Psychological MetaADEDB
Silent Myocardial Infarction MetaADEDB
Skeletal Injury MetaADEDB
Skin Lesion MetaADEDB
Sleep Disorder MetaADEDB
Spinning Sensation MetaADEDB
Sputum Discoloured MetaADEDB
Staphylococcal Infection MetaADEDB
Stomach Diseases MetaADEDB
Stomatitis ADReCS
Stridor MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sudden Death ADReCS
Surgery MetaADEDB
Tachycardia MetaADEDB
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Tension Headache MetaADEDB
Thirst ADReCS
Torsade De Pointes ADReCS
Torticollis MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheostomy MetaADEDB
Transaminases Increased MetaADEDB
Transplant Failure MetaADEDB
Trigeminal Neuralgia MetaADEDB
Troponin Increased MetaADEDB
Ulcer MetaADEDB
Urinary Retention MetaADEDB
Urine Output Increased MetaADEDB
Urticaria ADReCS
Vagus Nerve Disorder MetaADEDB
Varicose Vein MetaADEDB
Venous Insufficiency MetaADEDB
Ventricular Fibrillation MetaADEDB
Vomiting MetaADEDB
Wheeze MetaADEDB

InAADR: Drug-Protein-ADRs database