InAADR

Drug Information

Drug Name: Diflunisal (22494-42-4)
PubChem ID: 3059
SMILES: C1=CC(=C(C=C1C2=C(C=C(C=C2)F)F)C(=O)O)O
InchiKey: HUPFGZXOMWLGNK-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anti-Inflammatory Agents, Antirheumatic Agents, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 250.2
LogP: 3.0356
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 57.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Abscess MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Eeg MetaADEDB
Abnormal Faeces MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Vision MetaADEDB
Abortion MetaADEDB
Accommodation Disorder MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Acute Anaphylaxis SIDER
Acute Kidney Injury MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenopathy MetaADEDB
Adrenal Neoplasm MetaADEDB
Agranulocytosis ADReCS
Alcoholism MetaADEDB
Allergic Cutaneous Angiitis SIDER
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Alpha 1 Foetoprotein Increased MetaADEDB
Amyloid Neuropathies Familial MetaADEDB
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anemia MetaADEDB
Anemia Hemolytic MetaADEDB
Aneurysm MetaADEDB
Angioedema ADReCS
Anhedonia MetaADEDB
Anhidrosis MetaADEDB
Ankle Fracture MetaADEDB
Anorexia ADReCS
Anosmia MetaADEDB
Anxiety MetaADEDB
Aortic Aneurysm MetaADEDB
Apoplexy MetaADEDB
Aptyalism MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriopathic Disease MetaADEDB
Arthritis MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Atherosclerosis MetaADEDB
Atrial Tachycardia MetaADEDB
Back Ache MetaADEDB
Back Injury MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Birth Defect MetaADEDB
Bite MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Blindness Unilateral MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatine Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Sodium MetaADEDB
Blue Toe Syndrome MetaADEDB
Body Temperature Increased ADReCS
Bone Debridement MetaADEDB
Bone Disorder MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Oedema MetaADEDB
Bone Operation MetaADEDB
Bradypnoea MetaADEDB
Brain Concussion MetaADEDB
Brain Oedema MetaADEDB
Breakthrough Bleeding MetaADEDB
Bronchitis MetaADEDB
Bronchospasm ADReCS
Bruise MetaADEDB
Bulging MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
Calculus Urinary MetaADEDB
Cardiac Enlargement MetaADEDB
Carotid Artery Occlusion MetaADEDB
Cartilage Development Disorder MetaADEDB
Cellulitis MetaADEDB
Cellulitis Gangrenous ADReCS
Ceruloplasmin Decreased MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Chest Wall Mass MetaADEDB
Cholestasis ADReCS
Cirrhosis MetaADEDB
Colonic Obstruction MetaADEDB
Colonic Polyp MetaADEDB
Completed Suicide MetaADEDB
Confusional State ADReCS
Congenital Mitral Valve Incompetence MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Convulsions Grand Mal MetaADEDB
Cramp Muscle SIDER
Crying MetaADEDB
Cutaneous Ulcer MetaADEDB
Deafness ADReCS
Debridement MetaADEDB
Decreased Appetite ADReCS
Decreased Interest MetaADEDB
Dehydration MetaADEDB
Dental Implantation MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Diabetes MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disorientation ADReCS
Diverticular Perforation MetaADEDB
Diverticulitis MetaADEDB
Dizziness ADReCS
Drug Abuser MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Rash With Eosinophilia And Systemic Symptoms ADReCS
Drug Screen Positive MetaADEDB
Drug Tolerance MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Headache MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dysgeusia MetaADEDB
Dyslipidaemia MetaADEDB
Dyspepsia ADReCS
Dysphonia MetaADEDB
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dysuria ADReCS
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Emotional Distress MetaADEDB
Endodontic Procedure MetaADEDB
Endometrial Hyperplasia MetaADEDB
Eosinophilia MetaADEDB
Epidermal Necrosis ADReCS
Erectile Dysfunction MetaADEDB
Eructation ADReCS
Erythema ADReCS
Erythema Multiforme ADReCS
Esophageal Stenosis MetaADEDB
Essential Hypertension MetaADEDB
Exanthema MetaADEDB
Excessive Thirst MetaADEDB
Excoriation MetaADEDB
Extremity Pain MetaADEDB
Eye Pain MetaADEDB
Face Lift MetaADEDB
Fasciitis ADReCS
Fat Embolism MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Feeling Abnormal ADReCS
Femur Fracture MetaADEDB
Fever MetaADEDB
Flashing Lights MetaADEDB
Flatulence ADReCS
Floaters MetaADEDB
Flushing ADReCS
Foot Deformity MetaADEDB
Gastritis ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Fistula MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Perforation ADReCS
General Physical Health Deterioration MetaADEDB
Gynaecomastia MetaADEDB
Haematemesis MetaADEDB
Haematoma MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Hallucination ADReCS
Head Injury MetaADEDB
Headache ADReCS
Hearing Disorders MetaADEDB
Hearing Impaired ADReCS
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis C MetaADEDB
Hepatomegaly MetaADEDB
Hernia Hiatal MetaADEDB
High Blood Pressure MetaADEDB
Humerus Fracture MetaADEDB
Hyperhidrosis ADReCS
Hyperkeratosis MetaADEDB
Hyperlipaemia MetaADEDB
Hypersensitive Syndrome SIDER
Hypersensitivity ADReCS
Hypertonia MetaADEDB
Hypertonic Bladder MetaADEDB
Hypotension Orthostatic MetaADEDB
Impaired Healing MetaADEDB
Impaired Work Ability MetaADEDB
Incontinence MetaADEDB
Infection MetaADEDB
Infection Urinary Tract MetaADEDB
Infusion Related Reaction MetaADEDB
Injection Site Erythema MetaADEDB
Injection Site Phlebitis MetaADEDB
Insomnia ADReCS
Intentional Misuse MetaADEDB
Internal Fixation Of Fracture MetaADEDB
Ischaemic Stroke MetaADEDB
Jaundice ADReCS
Joint Range Of Motion Decreased MetaADEDB
Joint Stabilisation MetaADEDB
Keloid Scar MetaADEDB
Kidney Diseases MetaADEDB
Laceration MetaADEDB
Leucopenia MetaADEDB
Leukocytoclastic Vasculitis ADReCS
Light Sensitivity MetaADEDB
Liver Function Test Abnormal ADReCS
Loose Tooth MetaADEDB
Loss Of Consciousness ADReCS
Lung Adenocarcinoma MetaADEDB
Lung Edema MetaADEDB
Lung Infection MetaADEDB
Lyell MetaADEDB
Macrocytosis MetaADEDB
Mania MetaADEDB
Mean Cell Volume Abnormal MetaADEDB
Medical Device Removal MetaADEDB
Menstrual Disorder MetaADEDB
Mental Disorder MetaADEDB
Migraine MetaADEDB
Mouth Bleeding MetaADEDB
Mouth Pain MetaADEDB
Mucosal Dryness ADReCS
Mucous Membrane Disorder ADReCS
Multiple Myeloma MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Myofascial Pain Syndromes MetaADEDB
Nail Tinea MetaADEDB
Nasal Congestion MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Necrolysis Epidermal SIDER
Necrotising Fasciitis ADReCS
Neoplasm Recurrence MetaADEDB
Nephritis ADReCS
Nephritis Interstitial SIDER
Nephrotic Syndrome ADReCS
Nervousness ADReCS
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Oedema ADReCS
Oliguria MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Disorder MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteoporosis MetaADEDB
Osteoradionecrosis MetaADEDB
Overweight MetaADEDB
Pain MetaADEDB
Pain Postoperative MetaADEDB
Palpitations ADReCS
Paraesthesia ADReCS
Pco2 Decreased MetaADEDB
Peptic Ulcer ADReCS
Periarthritis MetaADEDB
Peripheral Artery Aneurysm MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Phlebothrombosis MetaADEDB
Phonophobia MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Physical Assault MetaADEDB
Platelet Count MetaADEDB
Pneumonia MetaADEDB
Pneumoperitoneum MetaADEDB
Pneumothorax MetaADEDB
Polyuria MetaADEDB
Poor Quality Drug Administered MetaADEDB
Posterior Capsule Opacification MetaADEDB
Primary Sequestrum MetaADEDB
Protein Total Decreased MetaADEDB
Protein Urine Present ADReCS
Proteinuria ADReCS
Pruritus ADReCS
Pulmonary Congestion MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Renal Failure ADReCS
Renal Impairment ADReCS
Retinal Artery Embolism MetaADEDB
Retinal Artery Occlusion MetaADEDB
Retinal Bleeding MetaADEDB
Rib Fracture MetaADEDB
Secondary Sequestrum MetaADEDB
Sensitivity Of Teeth MetaADEDB
Sequestrectomy MetaADEDB
Shock ADReCS
Sinusitis MetaADEDB
Somnolence ADReCS
Spinal Compression Fracture MetaADEDB
Splenomegaly MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stomatitis ADReCS
Sweating SIDER
Syncope ADReCS
Systemic Vasculitis MetaADEDB
Tension ADReCS
Theft MetaADEDB
Thrombocytopenia ADReCS
Tibia Fracture MetaADEDB
Tinnitus ADReCS
Toe Operation MetaADEDB
Tooth Disease MetaADEDB
Tooth Extraction MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Transient Ischaemic Attack MetaADEDB
Tubulointerstitial Nephritis ADReCS
Ulcer ADReCS
Upper Airway Obstruction MetaADEDB
Urticaria ADReCS
Vasculitis ADReCS
Venous Occlusion MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Wheeze MetaADEDB
Withdrawal Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database