InAADR

Drug Information

Drug Name: Diclofenac (15307-86-5)
PubChem ID: 3033
SMILES: C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
InchiKey: DCOPUUMXTXDBNB-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anti-Inflammatory Agents, Antirheumatic Agents, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 296.153
LogP: 4.3641
Ring Count: 2
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 49.33

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Acetylsalicylic acid (50-78-2) Disorder Gastrointestinal Additive Mechanisms behind the pharmacokinetic changes is the rates of absorption and renal clearance and competition for plasma protein binding Upper gastrointestinal bleeding among users of NSAIDs: a population-based cohort study in Denmark

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Hepatotoxicity Cytochrome P450 2C9 (P11712) The biotransformation of diclofenac to M2 is P450 2C9-dependent@ whereas metabolism of the drug to M1 and M3 involves mainly P450 3A4. Although P450s 2C9 and 3A4 both catalyze the bioactivation of diclofenac@ P450 2C9 is capable of producing the benzoquinone imine intermediate at lower drug concentrations which may be more clinically relevant. [ ADR Type 2 ] Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac
Hepatotoxicity Cytochrome P450 3A4 (P08684) The biotransformation of diclofenac to M2 is P450 2C9-dependent@ whereas metabolism of the drug to M1 and M3 involves mainly P450 3A4 Although P450s 2C9 and 3A4 both catalyze the bioactivation of diclofenac@ P450 2C9 is capable of producing the benzoquinone imine intermediate at lower drug concentrations which may be more clinically relevant

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference
5-hydroxydiclofenac Hepatotoxicity Liver Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity
N!5-dihydroxydiclofenac Hepatotoxicity Liver Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness MetaADEDB
Abnormal Dreams ADReCS
Abnormal Ecg MetaADEDB
Abnormal Vision MetaADEDB
Abscess ADReCS
Abscess Bacterial MetaADEDB
Abscess Periodontal SIDER
Accident MetaADEDB
Accommodation Disorder MetaADEDB
Aching Muscles MetaADEDB
Acholia MetaADEDB
Acidosis MetaADEDB
Acne ADReCS
Actinomycosis MetaADEDB
Acute Abdomen MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Injury MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenoma MetaADEDB
Adjustment Disorder MetaADEDB
Adrenal Neoplasm MetaADEDB
Afib MetaADEDB
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Agraphia MetaADEDB
Alanine Aminotransferase Increased SIDER
Alopecia ADReCS
Amblyopia ADReCS
Amnesia MetaADEDB
Amphetamine-Related Disorders MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anal Haemorrhage MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Reaction ADReCS
Anaphylaxis MetaADEDB
Androgen Deficiency MetaADEDB
Anemia Aplastic MetaADEDB
Anemia Hemolytic MetaADEDB
Anemia Hemolytic Autoimmune MetaADEDB
Anemia Iron-Deficiency MetaADEDB
Angiitis MetaADEDB
Angina Pectoris ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anorectal Disorder ADReCS
Anorexia ADReCS
Anticholinergic Syndrome MetaADEDB
Antiviral Drug Level Above Therapeutic MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Aortic Aneurysm MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy MetaADEDB
Aphagia MetaADEDB
Aphasia ADReCS
Aphthous Stomatitis ADReCS
Aplastic Anaemia ADReCS
Appetite Disorder ADReCS
Application Site Dryness ADReCS
Application Site Reaction ADReCS
Arrhythmia ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis ADReCS
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Arteriospasm Coronary MetaADEDB
Arthralgia ADReCS
Arthritis Gouty MetaADEDB
Arthritis Psoriatic MetaADEDB
Arthritis Rheumatoid MetaADEDB
Arthrodesis MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased SIDER
Aspiration Pneumonia MetaADEDB
Asterixis MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Asystole MetaADEDB
Atelectasis MetaADEDB
Atherosclerosis MetaADEDB
Atherosclerosis Obliterans MetaADEDB
Atrial Flutter MetaADEDB
Atrial Tachycardia MetaADEDB
Atrophy ADReCS
Av Dissociation MetaADEDB
Axillary Mass MetaADEDB
Azotaemia ADReCS
Azotemia MetaADEDB
B-Cell Lymphoma MetaADEDB
Back Injury MetaADEDB
Back Pain ADReCS
Bacterial Infections MetaADEDB
Band Neutrophil Percentage Decreased MetaADEDB
Basedow Disease MetaADEDB
Benign Biliary Neoplasm MetaADEDB
Benign Mesothelioma MetaADEDB
Benign Neoplasm Of Thyroid Gland MetaADEDB
Bicytopenia MetaADEDB
Bile Duct Cancer Stage Iii MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Pain ADReCS
Bleb MetaADEDB
Bleeding Time Prolonged ADReCS
Bleeding Vaginal SIDER
Blindness ADReCS
Blindness Transient MetaADEDB
Blister ADReCS
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Cholesterol Abnormal MetaADEDB
Blood Creatine Phosphokinase Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Immunoglobulin E MetaADEDB
Blood In Urine MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Body Height Decreased MetaADEDB
Body Odor SIDER
Body Temperature Increased ADReCS
Bone Pain ADReCS
Borderline Personality Disorder MetaADEDB
Bradycardia ADReCS
Brain Diseases MetaADEDB
Brain Oedema MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Cancer MetaADEDB
Breast Disorder SIDER
Breast Lump MetaADEDB
Breast Lump Removal MetaADEDB
Breast Pain MetaADEDB
Breath Odour ADReCS
Bronchitis ADReCS
Bullous Eruption ADReCS
Burning Sensation ADReCS
Bursitis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Candida Infection MetaADEDB
Candidiasis MetaADEDB
Candidiasis Of Mouth MetaADEDB
Candidiasis Of Vagina MetaADEDB
Carcinoma SIDER
Carcinoma Non-Small-Cell Lung MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Massage MetaADEDB
Cardiac Procedure Complication MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathies MetaADEDB
Cardiovascular Diseases MetaADEDB
Cardiovascular Disorder ADReCS
Cartilage Development Disorder MetaADEDB
Cataract Operation MetaADEDB
Catheterisation Cardiac MetaADEDB
Cellulitis MetaADEDB
Central Nervous System Lymphoma MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Infarction MetaADEDB
Cerebral Infarct MetaADEDB
Cerebration Impaired SIDER
Cerebrosclerosis MetaADEDB
Cerebrovascular Accident ADReCS
Chemical Eye Injury MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Cholangiolitis MetaADEDB
Cholecystolithiasis MetaADEDB
Cholestasis MetaADEDB
Choluria MetaADEDB
Chromaturia MetaADEDB
Colitis ADReCS
Colitis Ischaemic MetaADEDB
Colitis Ulcerative ADReCS
Colonic Neoplasms MetaADEDB
Colonic Polyp MetaADEDB
Colonic Stenosis MetaADEDB
Color Blindness MetaADEDB
Coma ADReCS
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Cystic Kidney Disease MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congestive Cardiomyopathy ADReCS
Conjunctival Hyperaemia ADReCS
Conjunctivitis ADReCS
Conjunctivitis Allergic SIDER
Constipation ADReCS
Contusion ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Corneal Deposits ADReCS
Corneal Disorder ADReCS
Corneal Epithelium Defect MetaADEDB
Corneal Erosion ADReCS
Corneal Infiltrates ADReCS
Corneal Lesion ADReCS
Corneal Oedema ADReCS
Corneal Opacity ADReCS
Corneal Perforation ADReCS
Corneal Pigmentation MetaADEDB
Corneal Scar MetaADEDB
Corneal Thinning ADReCS
Corneal Ulcer MetaADEDB
Coronary Artery Thrombosis MetaADEDB
Coronary Vasospasm MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Creatine Phosphokinase Increased SIDER
Creatinine Increased SIDER
Crohn Disease MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Culture Positive MetaADEDB
Cystitis ADReCS
Cystitis Noninfective ADReCS
Cystocele MetaADEDB
Cytomegalovirus Antigen MetaADEDB
Cytomegalovirus Enterocolitis MetaADEDB
Deafness ADReCS
Death ADReCS
Decreased Activity MetaADEDB
Decreased Appetite ADReCS
Dehydration MetaADEDB
Delirium MetaADEDB
Demyelinating Diseases MetaADEDB
Dental Abscess MetaADEDB
Dental Caries ADReCS
Depressed Level Of Consciousness MetaADEDB
Depression ADReCS
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatitis Contact ADReCS
Dermatitis Exfoliative ADReCS
Dermatomyositis MetaADEDB
Diabetes MetaADEDB
Diabetic Neuropathy MetaADEDB
Diaphragmatic Disorder MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diarrhoea Haemorrhagic ADReCS
Dilatation Ventricular MetaADEDB
Diplopia ADReCS
Discitis MetaADEDB
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disorder Retinal MetaADEDB
Disorientation ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Distention SIDER
Disturbance In Attention ADReCS
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dreaming Abnormal ADReCS
Drowsiness SIDER
Drug Abuser MetaADEDB
Drug Administered At Inappropriate Site MetaADEDB
Drug Delivery System Malfunction MetaADEDB
Drug Diversion MetaADEDB
Drug Eruptions MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Ineffective ADReCS
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Duodenal Ulcer ADReCS
Duodenal Ulcer Perforation MetaADEDB
Duodenitis MetaADEDB
Dysarthria MetaADEDB
Dysgeusia ADReCS
Dysmenorrhea MetaADEDB
Dyspepsia ADReCS
Dyspnea MetaADEDB
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dysthymic Disorder ADReCS
Dysuria ADReCS
Ear Pain ADReCS
Ecchymosis ADReCS
Eczema ADReCS
Edema MetaADEDB
Ejaculation Failure MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Embolism Pulmonary MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalitis MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalitis Viral MetaADEDB
Encephalopathy MetaADEDB
Endocarditis MetaADEDB
Endometriosis MetaADEDB
Endophthalmitis MetaADEDB
Endoscopy Gastrointestinal Abnormal MetaADEDB
Enterocolitis MetaADEDB
Enterocolitis Bacterial MetaADEDB
Enterocolitis Haemorrhagic ADReCS
Eosinophilia ADReCS
Epidermal Necrosis ADReCS
Epidermolysis MetaADEDB
Epilepsies Myoclonic MetaADEDB
Epilepsy MetaADEDB
Epilepsy Tonic-Clonic MetaADEDB
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erosive Balanitis MetaADEDB
Erosive Gastritis MetaADEDB
Eructation ADReCS
Eruption SIDER
Erythema ADReCS
Erythema Migrans MetaADEDB
Erythema Multiforme ADReCS
Erythema Of Eyelid ADReCS
Escherichia Urinary Tract Infection MetaADEDB
Esophageal Diseases MetaADEDB
Exacerbation Of Asthma ADReCS
Exanthema MetaADEDB
Exposure To Toxic Agent MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Eye Allergy ADReCS
Eye Discharge ADReCS
Eye Disorder SIDER
Eye Inflammation ADReCS
Eye Injuries MetaADEDB
Eye Irritation ADReCS
Eye Pain ADReCS
Eye Pruritus ADReCS
Eye Swelling MetaADEDB
Eyelid Oedema ADReCS
Eyelids Pruritus ADReCS
Face Oedema ADReCS
Facial Bones Fracture MetaADEDB
Facial Palsy MetaADEDB
Faeces Discoloured MetaADEDB
Fallopian Tube Disorder MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Feeling Abnormal ADReCS
Fever MetaADEDB
Fib MetaADEDB
Fibromyalgia MetaADEDB
Flatulence ADReCS
Floaters MetaADEDB
Fluid Retention ADReCS
Flushing ADReCS
Foetal Growth Retardation MetaADEDB
Folliculitis MetaADEDB
Forearm Fracture MetaADEDB
Furuncle ADReCS
Furunculosis SIDER
Gait Disturbance ADReCS
Gambling MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Bypass MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Ph Decreased ADReCS
Gastric Ulcer ADReCS
Gastric Ulcer Haemorrhage MetaADEDB
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Diseases MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Erosion MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Hemorrhage MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Perforation MetaADEDB
Gastrointestinal Symptom Nos SIDER
Gastrointestinal Ulcer ADReCS
General Physical Health Deterioration MetaADEDB
Genital Disorder Female MetaADEDB
Genital Erosion MetaADEDB
Genital Ulceration MetaADEDB
Gingivitis ADReCS
Glaucoma Open-Angle MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Membranous MetaADEDB
Glossitis ADReCS
Gout ADReCS
Granulocytosis MetaADEDB
Gum Neoplasm Malignant Stage Unspecified MetaADEDB
Haemangioma MetaADEDB
Haematemesis ADReCS
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Haemorrhage Rectum MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Haemorrhoids ADReCS
Hair Disorder ADReCS
Hallucination ADReCS
Hand Fracture MetaADEDB
Hand Osteoarthritis SIDER
Head Injury MetaADEDB
Headache ADReCS
Hearing Impaired ADReCS
Heart Failure MetaADEDB
Heart Rate Abnormal MetaADEDB
Heart Valve Incompetence MetaADEDB
Heartburn ADReCS
Hemiparesis MetaADEDB
Hemoglobinuria MetaADEDB
Hemolysis MetaADEDB
Hemorrhagic Colitis SIDER
Henoch-Schonlein Purpura ADReCS
Hepatic Cirrhosis ADReCS
Hepatic Congestion MetaADEDB
Hepatic Encephalopathy MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Mass MetaADEDB
Hepatic Necrosis ADReCS
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatitis Chronic MetaADEDB
Hepatitis Fulminant ADReCS
Hepatobiliary Disease SIDER
Hepatomegaly MetaADEDB
Hepatorenal Syndrome ADReCS
Hereditary Disorder SIDER
Hernia ADReCS
Herpes Nos SIDER
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
Hip Fracture MetaADEDB
Hip Surgery MetaADEDB
Hospitalisation MetaADEDB
Hyperaemia ADReCS
Hyperaesthesia ADReCS
Hyperalgesia MetaADEDB
Hyperammonaemia MetaADEDB
Hyperchlorhydria ADReCS
Hypercholesterolaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalemia MetaADEDB
Hyperkinesia ADReCS
Hypersexuality MetaADEDB
Hypertension ADReCS
Hypertonia ADReCS
Hypertrophy ADReCS
Hyperventilation ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Facial MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypoglycaemia ADReCS
Hypokalaemia MetaADEDB
Hypokinesia ADReCS
Hypotension ADReCS
Hypothermia MetaADEDB
Hypothyroid MetaADEDB
Hypotonia MetaADEDB
Hypovolaemic Shock MetaADEDB
Ild MetaADEDB
Ill-Defined Disorder ADReCS
Illusion MetaADEDB
Immune Reconstitution Syndrome MetaADEDB
Immune System Disorder SIDER
Impingement Syndrome MetaADEDB
Inappropriate Adh Syndrome MetaADEDB
Incision Site Infection MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Inflammation MetaADEDB
Influenza ADReCS
Injection Site Erythema MetaADEDB
Injection Site Nodule MetaADEDB
Injection Site Reaction ADReCS
Insomnia ADReCS
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Displacement MetaADEDB
Intestinal Diseases MetaADEDB
Intestinal Perforation ADReCS
Intracardiac Thrombus MetaADEDB
Intracranial Aneurysm MetaADEDB
Intraocular Pressure Increased ADReCS
Intubation MetaADEDB
Iritis ADReCS
Irritability ADReCS
Itch MetaADEDB
Jaundice ADReCS
Jaw Disorder MetaADEDB
Joint Arthroplasty MetaADEDB
Kaposi Sarcoma MetaADEDB
Keratitis ADReCS
Keratitis Bacterial MetaADEDB
Keratosis Actinic MetaADEDB
Kidney Diseases MetaADEDB
Kidney Function Abnormal ADReCS
Kidney Rupture MetaADEDB
Kidney Tubular Necrosis Acute MetaADEDB
Laceration MetaADEDB
Lack Of Drug Effect SIDER
Lacrimal Disorder ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Lacunar Infarction MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Large Intestinal Ulcer MetaADEDB
Large Intestine Perforation MetaADEDB
Laryngeal Oedema ADReCS
Laryngitis ADReCS
Laryngospasm ADReCS
Leg Cramps ADReCS
Legionella MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia ADReCS
Life Support MetaADEDB
Limb Injury MetaADEDB
Lip Swelling ADReCS
Liver Cirrhosis MetaADEDB
Liver Diseases MetaADEDB
Liver Failure Acute MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Employment MetaADEDB
Loss Of Weight MetaADEDB
Low Back Pain MetaADEDB
Lung Adenocarcinoma MetaADEDB
Lung Cancer Metastatic MetaADEDB
Lung Edema MetaADEDB
Lung Infection MetaADEDB
Lupus Erythematosus Systemic MetaADEDB
Lyell MetaADEDB
Lymphadenopathy ADReCS
Lymphangioma MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Mammoplasty MetaADEDB
Mastoiditis MetaADEDB
Melaena ADReCS
Memory Impairment ADReCS
Meningitis ADReCS
Meningitis Aseptic ADReCS
Meniscus Lesion MetaADEDB
Mental Disability ADReCS
Mental Disorder SIDER
Metabolic Disorder MetaADEDB
Metamorphopsia MetaADEDB
Metaplasia MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Microangiopathic Haemolytic Anaemia MetaADEDB
Micrognathia MetaADEDB
Migraine ADReCS
Miller Fisher Syndrome MetaADEDB
Mixed Hepatocellular-Cholestatic Injury MetaADEDB
Mouth Ulcer MetaADEDB
Mouth Ulceration ADReCS
Movement Disorder MetaADEDB
Mucosal Erosion MetaADEDB
Mucosal Inflammation MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Organ Failure MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Rigidity ADReCS
Muscle Spasms ADReCS
Muscle Strain ADReCS
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Musculoskeletal Stiffness ADReCS
Myalgia ADReCS
Myasthenia SIDER
Mycobacterium Tuberculosis Infection MetaADEDB
Myocardial Infarction ADReCS
Myoclonus MetaADEDB
Myoglobinuria MetaADEDB
Nail Disorder ADReCS
Narcotic Intoxication MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Neck Pain ADReCS
Neck Stiffness ADReCS
Necrolysis Epidermal SIDER
Necrosis ADReCS
Necrotising Fasciitis MetaADEDB
Neoplasm Malignant ADReCS
Neovascularisation MetaADEDB
Nephritis ADReCS
Nephritis Interstitial SIDER
Nephropathy ADReCS
Nephrosis Lipoid MetaADEDB
Nephrotic Syndrome ADReCS
Nervous System Diseases MetaADEDB
Nervous System Disorder SIDER
Nervous System Malformations MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuralgia MetaADEDB
Neuritis ADReCS
Neuroblastoma MetaADEDB
Neuropathy Peripheral ADReCS
Neutropenia Neonatal MetaADEDB
Neutropenic Sepsis MetaADEDB
Night Blindness ADReCS
Nightmare ADReCS
Nocturia ADReCS
Nodule ADReCS
Nuchal Rigidity ADReCS
Ocular Hyperaemia ADReCS
Ocular Hypertension MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Disorder ADReCS
Oesophagitis ADReCS
Oliguria ADReCS
Open Reduction Of Fracture MetaADEDB
Oral Disorder MetaADEDB
Oral Polypectomy MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteoarthritis ADReCS
Osteomyelitis MetaADEDB
Ovarian Haematoma MetaADEDB
Oxygen Supplementation MetaADEDB
Pain ADReCS
Pain In Throat MetaADEDB
Pain Postoperative MetaADEDB
Painful Respiration MetaADEDB
Pallor MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitations ADReCS
Palsies MetaADEDB
Pancreatitis ADReCS
Pancytopenia ADReCS
Papule ADReCS
Paraesthesia ADReCS
Partial Hearing Loss SIDER
Pelvic Prolapse MetaADEDB
Peptic Ulcer ADReCS
Peripheral Paralysis MetaADEDB
Peripheral Sensorimotor Neuropathy MetaADEDB
Pharyngeal Inflammation MetaADEDB
Pharyngitis ADReCS
Pharyngolaryngeal Pain MetaADEDB
Phlebitis ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Piloerection MetaADEDB
Platelet Count MetaADEDB
Pleural Adhesion MetaADEDB
Pleurisy MetaADEDB
Pneumococcal Infection MetaADEDB
Pneumonia ADReCS
Po2 MetaADEDB
Pollakiuria ADReCS
Polycystic Ovaries MetaADEDB
Polyuria ADReCS
Post Procedural Haematoma MetaADEDB
Post Procedural Pain MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Postoperative Hemorrhage MetaADEDB
Postoperative Wound Complication MetaADEDB
Prenatal Exposure Delayed Effects MetaADEDB
Proctalgia MetaADEDB
Proctitis ADReCS
Proctocolitis MetaADEDB
Prostate Infection MetaADEDB
Prostatic Specific Antigen Increased ADReCS
Protein Total Decreased MetaADEDB
Protein Urine Present ADReCS
Proteinuria ADReCS
Pruritus ADReCS
Pseudopolyp MetaADEDB
Psychotic Disorder ADReCS
Pulmonary Arrest MetaADEDB
Pulmonary Function Test Decreased ADReCS
Punctate Keratitis ADReCS
Purpura ADReCS
Purpura Fulminans MetaADEDB
Purpura Schoenlein-Henoch MetaADEDB
Purpura Thrombocytopenic MetaADEDB
Purpuric Rash SIDER
Purulent Discharge MetaADEDB
Pyrexia ADReCS
Quadriplegia MetaADEDB
Radical Mastectomy MetaADEDB
Radius Fracture MetaADEDB
Rash ADReCS
Rash Maculo-Papular ADReCS
Rash Pustular ADReCS
Raynaud Phenomenon MetaADEDB
Rectal Disorder SIDER
Rectal Haemorrhage ADReCS
Rectal Polyp MetaADEDB
Rectal Ulcer MetaADEDB
Redness SIDER
Reflux Esophagitis MetaADEDB
Renal Cyst MetaADEDB
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Function Abnormal ADReCS
Renal Impairment ADReCS
Renal Insufficiency MetaADEDB
Renal Papillary Necrosis ADReCS
Respiratory Depression ADReCS
Respiratory Disorder ADReCS
Respiratory Rate Increased MetaADEDB
Retinal Infarction MetaADEDB
Retinal Injury MetaADEDB
Retinogram Abnormal MetaADEDB
Reye Syndrome MetaADEDB
Rhabdomyolysis MetaADEDB
Rheumatism SIDER
Rhinitis ADReCS
Rhinorrhea MetaADEDB
Rhonchi MetaADEDB
Rupture Of Spleen MetaADEDB
Sacroiliitis MetaADEDB
Scleroderma MetaADEDB
Scotoma ADReCS
Scratch MetaADEDB
Seborrhoeic Dermatitis ADReCS
Secondary Anaemia SIDER
Seizures MetaADEDB
Sensation Of Heaviness MetaADEDB
Sensory Disturbance ADReCS
Sepsis ADReCS
Septic Arthritis Staphylococcal MetaADEDB
Shock ADReCS
Sinoatrial Block MetaADEDB
Sinus Polyp MetaADEDB
Sinusitis ADReCS
Skin Burning Sensation ADReCS
Skin Cancer ADReCS
Skin Carcinoma SIDER
Skin Discolouration ADReCS
Skin Diseases MetaADEDB
Skin Disorder ADReCS
Skin Exfoliation ADReCS
Skin Hypertrophy ADReCS
Skin Irritation ADReCS
Skin Lesion MetaADEDB
Skin Mass ADReCS
Skin Nodule ADReCS
Skin Odour Abnormal ADReCS
Skin Reaction ADReCS
Skin Ulcer ADReCS
Sleep Apnea MetaADEDB
Sleep Disorder ADReCS
Small Intestine Ulcer MetaADEDB
Social Avoidant Behaviour ADReCS
Somnolence ADReCS
Speech Disorder ADReCS
Spinal Cord Compression MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spondylitis MetaADEDB
Spondylitis Ankylosing MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stinging SIDER
Stomach Diseases MetaADEDB
Stomach Ulcer MetaADEDB
Stomatitis ADReCS
Stress Incontinence MetaADEDB
Stress Symptoms MetaADEDB
Stroke MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Sudden Death MetaADEDB
Sweating SIDER
Sweating Increased SIDER
Swelling ADReCS
Swelling Of Eyelid SIDER
Swollen Tongue MetaADEDB
Syncope ADReCS
Tachycardia ADReCS
Tension ADReCS
Testicular Disorder ADReCS
Thalamic Infarction MetaADEDB
Thinking Abnormal ADReCS
Thirst ADReCS
Thrombocytopenia ADReCS
Thromboembolism MetaADEDB
Thrombosis MetaADEDB
Thrombotic Microangiopathies MetaADEDB
Tic ADReCS
Tinnitus ADReCS
Tongue Coated ADReCS
Tongue Discolouration ADReCS
Tooth Abscess ADReCS
Tooth Erosion MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Tracheal Haemorrhage MetaADEDB
Trance MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Triple Vessel Bypass Graft MetaADEDB
Tubulointerstitial Nephritis ADReCS
Tumour Lysis Syndrome MetaADEDB
Ulcer ADReCS
Ulcerative Keratitis ADReCS
Ulcerative Stomatitis SIDER
Unconsciousness MetaADEDB
Unspecified Disorder Of Intestine SIDER
Upper Gastrointestinal Bleeding MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Urea Urine Increased MetaADEDB
Urethral Disorder SIDER
Urinary Tract Disorder SIDER
Urination Disorders MetaADEDB
Urine Analysis Abnormal MetaADEDB
Urine Output Increased ADReCS
Urticaria ADReCS
Urticaria Chronic MetaADEDB
Uterine Atony MetaADEDB
Uterine Bleeding MetaADEDB
Vaginal Haemorrhage ADReCS
Vaginal Prolapse MetaADEDB
Vascular Purpura ADReCS
Vasculitis ADReCS
Vasodilation SIDER
Vasodilation Procedure ADReCS
Venous Thrombosis MetaADEDB
Ventricular Extrasystoles ADReCS
Ventricular Fibrillation MetaADEDB
Vertigo ADReCS
Vesiculobullous Rash SIDER
Viral Infection ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vitreous Disorder MetaADEDB
Vitreous Floaters ADReCS
Vomiting ADReCS
Weight Abnormal ADReCS
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Loss MetaADEDB
Wheeze MetaADEDB
White Blood Cell Count Abnormal MetaADEDB
Withdrawal Syndrome MetaADEDB
Withdrawn SIDER
Wound Complication MetaADEDB
Wound Treatment MetaADEDB
Wrist Fracture MetaADEDB
Wrist Surgery MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database