InAADR

Drug Information

Drug Name: Danazol (17230-88-5)
PubChem ID: 28417
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5
InchiKey: POZRVZJJTULAOH-LHZXLZLDSA-N
Therapeutic Category: Estrogen Antagonists, Estrogen Receptor Modulators, Hormone Antagonists, Hormones

Computed Drug Properties

Molecular Weight (dalton): 337.463
LogP: 4.221
Ring Count: 1
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 46.26

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Carbamazepine (298-46-4) Carbamazepine Toxicity Synergistic Danazol inhibits the metabolism (by the epoxide-trans-diol pathway) of carbamazepine by the liver Carbamazepine-danazol drug interaction: its mechanism examined by a stable isotope technique

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Lfts MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acne ADReCS
Acne Vulgaris MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Injury MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Sinusitis MetaADEDB
Adenoma MetaADEDB
Adenoma Benign ADReCS
Adenoma Liver Cell MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Alanine Aminotransferase Increased MetaADEDB
Allergic Vasculitis MetaADEDB
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Amenorrhoea ADReCS
Amnesia MetaADEDB
Anaemia MetaADEDB
Anal Haemorrhage MetaADEDB
Anemia Aplastic MetaADEDB
Anemia Hemolytic Autoimmune MetaADEDB
Aneurysm MetaADEDB
Aneurysm Ruptured MetaADEDB
Angioedema MetaADEDB
Angioedemas Hereditary MetaADEDB
Anion Gap Increased MetaADEDB
Anorexia MetaADEDB
Anti-Erythropoietin Antibody Positive MetaADEDB
Antiphospholipid Syndrome MetaADEDB
Anxiety ADReCS
Anxiety Disorders MetaADEDB
Apoplexy MetaADEDB
Appetite Disorder ADReCS
Aptyalism MetaADEDB
Arrhythmia MetaADEDB
Arterial Thrombosis MetaADEDB
Arteriosclerosis MetaADEDB
Arthralgia ADReCS
Arthritis MetaADEDB
Arthropathy MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asthenia ADReCS
Autoimmune Disorder MetaADEDB
B-Cell Small Lymphocytic Lymphoma MetaADEDB
Back Pain ADReCS
Bedridden MetaADEDB
Benign Intracranial Hypertension ADReCS
Bile Duct Neoplasms MetaADEDB
Birth Defect MetaADEDB
Bladder Cancer MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Blast Cells Present MetaADEDB
Bleeding Vaginal MetaADEDB
Blindness Transient MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Blister MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Insulin Increased ADReCS
Blood Potassium Increased MetaADEDB
Blood Pressure Increased ADReCS
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Depression MetaADEDB
Bone Marrow Disorder MetaADEDB
Brain Diseases MetaADEDB
Brain Oedema MetaADEDB
Breast Atrophy ADReCS
Breast Cellulitis MetaADEDB
Breast Discharge ADReCS
Breast Enlargement MetaADEDB
Breast Neoplasms MetaADEDB
Bruise MetaADEDB
Burn Oesophageal MetaADEDB
Calcinosis MetaADEDB
Carcinoma Hepatocellular MetaADEDB
Carcinoma Of The Colon MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carotid Artery Thrombosis MetaADEDB
Carpal Tunnel Syndrome ADReCS
Cataract ADReCS
Catheter Sepsis MetaADEDB
Cellulitis MetaADEDB
Cerebral Aspergillosis MetaADEDB
Cerebral Ischaemia MetaADEDB
Chest Pain MetaADEDB
Chest Wall Pain MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Chills ADReCS
Cholangitis Sclerosing MetaADEDB
Cholestasis MetaADEDB
Cholestasis Intrahepatic MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Claustrophobia MetaADEDB
Clostridial Infection MetaADEDB
Cmv Infection MetaADEDB
Colitis Ischaemic MetaADEDB
Condition Aggravated MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Cortical Laminar Necrosis MetaADEDB
Costovertebral Angle Tenderness MetaADEDB
Crackles Lung MetaADEDB
Cramp Muscle SIDER
Cranial Nerve Disorder MetaADEDB
Cystitis MetaADEDB
Cytomegalovirus Gastroenteritis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Death MetaADEDB
Depression ADReCS
Depressive Disorder MetaADEDB
Dermal Cyst MetaADEDB
Dermatitis ADReCS
Diabetes MetaADEDB
Difficulty In Walking MetaADEDB
Dilatation Atrial MetaADEDB
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disorder Renal MetaADEDB
Dizziness ADReCS
Drug Dispensing Error MetaADEDB
Drug Ineffective MetaADEDB
Drug Interaction MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Duodenitis MetaADEDB
Dyslipidaemia MetaADEDB
Dyslipidemias MetaADEDB
Dysphonia ADReCS
Easy Bruisability MetaADEDB
Ebv Infection MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Embolism Venous MetaADEDB
Endometriosis MetaADEDB
Enlarged Clitoris ADReCS
Enteritis Necroticans MetaADEDB
Eosinophilia ADReCS
Eosinophilic Myocarditis MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Erythrocytosis SIDER
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Extremity Pain MetaADEDB
Facial Bones Fracture MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue ADReCS
Feeling Abnormal MetaADEDB
Fib MetaADEDB
Fibroma MetaADEDB
Fibromyalgia MetaADEDB
Fluid Retention ADReCS
Flushing ADReCS
Focal Nodular Hyperplasia MetaADEDB
Gastroenteritis ADReCS
General Physical Health Deterioration MetaADEDB
Gingival Bleeding ADReCS
Glycogen Storage Disease Type V MetaADEDB
Guillain-Barre Syndrome ADReCS
Haematological Malignancy MetaADEDB
Haematoma MetaADEDB
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemophilus Infection MetaADEDB
Haemorrhage ADReCS
Hamartoma MetaADEDB
Headache ADReCS
Hearing Loss Bilateral MetaADEDB
Hearing Loss Sensorineural MetaADEDB
Heart Attack MetaADEDB
Hematuria MetaADEDB
Hemoglobinuria Paroxysmal MetaADEDB
Hemorrhage MetaADEDB
Hepatic Adenoma ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Neoplasm ADReCS
Hepatic Neoplasm Malignant ADReCS
Hepatitis MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatitis Infectious Mononucleosis MetaADEDB
Hepatomegaly MetaADEDB
Hepatosplenomegaly MetaADEDB
Hepatotoxicity MetaADEDB
Hereditary Angioedema Types I And Ii MetaADEDB
Hirsutism ADReCS
Hoarseness SIDER
Hot Flashes MetaADEDB
Hypercalcemia MetaADEDB
Hyperhidrosis ADReCS
Hyperinsulinism ADReCS
Hyperlipoproteinemias MetaADEDB
Hyperprolactinemia MetaADEDB
Hypertension ADReCS
Hypertrophy ADReCS
Hypoalbuminaemia MetaADEDB
Hypoalphalipoproteinemias MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypothyroid MetaADEDB
Hypovolaemic Shock MetaADEDB
Idiopathic Intracranial Hypertension With Papilledema MetaADEDB
Immunodeficiency Common Variable MetaADEDB
Impaired Driving Ability MetaADEDB
Increased Insulin Requirement ADReCS
Increased Platelet Count MetaADEDB
Infarction ADReCS
Infusion Site Mobility Decreased MetaADEDB
Interstitial Lung Disease ADReCS
Interstitial Pneumonia SIDER
Intestinal Infarction MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Intracranial Aneurysm MetaADEDB
Intracranial Pressure Increased ADReCS
Iron Deficiency Anaemia MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Jaundice Obstructive MetaADEDB
Joint Lock ADReCS
Joint Range Of Motion Decreased MetaADEDB
Joint Sprain MetaADEDB
Joint Swelling ADReCS
Kidney Pain MetaADEDB
Knee Arthroplasty MetaADEDB
Knee Operation MetaADEDB
Laboratory Test Abnormal ADReCS
Leiomyoma MetaADEDB
Leukocytosis ADReCS
Leukopenia ADReCS
Libido Disorder ADReCS
Libido Increased MetaADEDB
Liver Diseases MetaADEDB
Liver Failure Acute MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lower Respiratory Tract Infection Bacterial MetaADEDB
Lung Fibrosis MetaADEDB
Lymphoma MetaADEDB
Menorrhagia MetaADEDB
Menstrual Disorder ADReCS
Menstruation Disturbances MetaADEDB
Mesenteric Artery Thrombosis MetaADEDB
Metrorrhagia ADReCS
Mitral Valve Stenosis MetaADEDB
Mood Disorders MetaADEDB
Mood Swings ADReCS
Multiple Myeloma MetaADEDB
Muscle Cramp MetaADEDB
Muscle Spasms ADReCS
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness MetaADEDB
Myelodysplasia MetaADEDB
Myocardial Infarction ADReCS
Nasal Congestion ADReCS
Nausea ADReCS
Necrotising Colitis MetaADEDB
Neoplasm ADReCS
Neoplasm Recurrence MetaADEDB
Nephrolithiasis MetaADEDB
Nervousness ADReCS
Neuropathy Peripheral MetaADEDB
Neutropenia MetaADEDB
Nightmare MetaADEDB
Non-Hodgkin Lymphoma MetaADEDB
Non-Hodgkin Lymphoma Recurrent MetaADEDB
Obsessive Thoughts MetaADEDB
Oedema ADReCS
Onychophagia MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Ovarian Adenoma MetaADEDB
Pain MetaADEDB
Pain Of Skin MetaADEDB
Palpitations ADReCS
Pancreatitis ADReCS
Pancytopenia MetaADEDB
Panic Attack MetaADEDB
Papilledema MetaADEDB
Paraesthesia ADReCS
Paronychia MetaADEDB
Peliosis Hepatis ADReCS
Pelvic Pain ADReCS
Peripheral Arterial Occlusive Disease MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Plasmacytosis MetaADEDB
Platelet Count MetaADEDB
Platelet Count Increased ADReCS
Pneumomediastinum MetaADEDB
Pneumonia ADReCS
Polycythaemia ADReCS
Primary Myelofibrosis MetaADEDB
Prostatitis MetaADEDB
Protein Total Increased MetaADEDB
Prothrombin Time MetaADEDB
Pruritus ADReCS
Pseudotumor Cerebri MetaADEDB
Pulmonary Emphysema MetaADEDB
Purpura ADReCS
Purpura Thrombocytopenic MetaADEDB
Purpura Thrombocytopenic Idiopathic MetaADEDB
Pyrexia ADReCS
Quadriparesis MetaADEDB
Rash ADReCS
Raynaud Phenomenon MetaADEDB
Red Blood Cell Schistocytes Present MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Atrophy MetaADEDB
Renal Function Test Abnormal MetaADEDB
Renal Haematoma MetaADEDB
Renal Impairment MetaADEDB
Renal Insufficiency MetaADEDB
Respiratory Fume Inhalation Disorder MetaADEDB
Rhabdomyolysis MetaADEDB
Rupture Of Spleen MetaADEDB
Scar MetaADEDB
Schizophrenia Paranoid Type MetaADEDB
Scleroderma MetaADEDB
Seborrhoea ADReCS
Seborrhoeic Dermatitis ADReCS
Shock ADReCS
Sinus Bradycardia MetaADEDB
Sinus Thrombosis Intracranial MetaADEDB
Sinusitis Bacterial MetaADEDB
Sjogren Syndrome MetaADEDB
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Lesion MetaADEDB
Sleep Disorder ADReCS
Sleep Initiation And Maintenance Disorders MetaADEDB
Spermatogenesis Abnormal ADReCS
Splenectomy MetaADEDB
Splenic Diseases MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stress MetaADEDB
Subarachnoid Hemorrhage MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Surgery MetaADEDB
Sweating SIDER
Swelling ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tachyphrenia MetaADEDB
Tension ADReCS
Therapeutic Response Decreased MetaADEDB
Throat Sore SIDER
Throat Tightness MetaADEDB
Thrombocytopenia ADReCS
Thrombosis MetaADEDB
Thyroid Function Test MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Upper Limb Fracture MetaADEDB
Urinary Tract Infection Pseudomonal MetaADEDB
Urinary Tract Infection Staphylococcal MetaADEDB
Urticaria ADReCS
Vaginal Dryness SIDER
Vascular Purpura ADReCS
Vasculitic Rash MetaADEDB
Vasculitis Cerebral MetaADEDB
Ventricular Fibrillation MetaADEDB
Viith Nerve Paralysis MetaADEDB
Visual Disturbance ADReCS
Visual Impairment ADReCS
Voice Alteration ADReCS
Voice Disorders MetaADEDB
Vomiting ADReCS
Vulvovaginal Discomfort ADReCS
Vulvovaginal Dryness ADReCS
Weakness SIDER
Weight Decreased ADReCS
Weight Gain MetaADEDB
Weight Increased ADReCS

InAADR: Drug-Protein-ADRs database