Drug Name: | Danazol (17230-88-5) |
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PubChem ID: | 28417 |
SMILES: | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5 |
InchiKey: | POZRVZJJTULAOH-LHZXLZLDSA-N |
Therapeutic Category: | Estrogen Antagonists, Estrogen Receptor Modulators, Hormone Antagonists, Hormones |
Molecular Weight (dalton) | : | 337.463 |
LogP | : | 4.221 |
Ring Count | : | 1 |
Hydrogen Bond Acceptor Count | : | 3 |
Hydrogen Bond Donor Count | : | 1 |
Total Polar Surface Area | : | 46.26 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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Carbamazepine (298-46-4) | Carbamazepine Toxicity | Synergistic | Danazol inhibits the metabolism (by the epoxide-trans-diol pathway) of carbamazepine by the liver | Carbamazepine-danazol drug interaction: its mechanism examined by a stable isotope technique |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category