| Drug Name: | Ceftriaxone (73384-59-5) |
|---|---|
| PubChem ID: | 5896995 |
| SMILES: | CN1C(=NC(=O)C(=O)N1)SCC2=C(N3C(C(C3=O)NC(=O)/C(=NOC)/C4=CSC(=N4)N)SC2)C(=O)O |
| InchiKey: | VAAUVRVFOQPIGI-GYRAYZOKSA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents |
| Molecular Weight (dalton) | : | 554.592 |
| LogP | : | -1.6113 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 14 |
| Hydrogen Bond Donor Count | : | 4 |
| Total Polar Surface Area | : | 214.96 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Warfarin (81-81-2) | Hypoprothrombinaemia | Additive | Cephalosporins with an N-methylthiotetrazole side-chain can, like the oral anticoagulants, act as vitamin K antagonists to reduce the production of some blood clotting factors. They can therefore cause bleeding on their own. | Hypoprothrombobinaemic bleeding associated with ceftriaxone |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category