InAADR

Drug Information

Drug Name: Cefotetan (69712-56-7)
PubChem ID: 53025
SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C4SC(=C(C(=O)N)C(=O)O)S4)OC)SC2)C(=O)O
InchiKey: SRZNHPXWXCNNDU-RHBCBLIFSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 575.632
LogP: -1.3975
Ring Count: 1
Hydrogen Bond Acceptor Count: 14
Hydrogen Bond Donor Count: 4
Total Polar Surface Area: 219.93

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Warfarin (81-81-2) Platelet Dysfunction Additive Cephalosporins with an N-methylthiotetrazole side-chain can, like the oral anticoagulants, act as vitamin K antagonists to reduce the production of some blood clotting factors. They can therefore cause bleeding on their own. Cefotetan and hypoprothrombinemia

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Acute Kidney Injury MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anemia MetaADEDB
Anemia Hemolytic MetaADEDB
Aplastic Anaemia ADReCS
Aspartate Aminotransferase Increased ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Bilirubin Increased ADReCS
Blood Creatinine Increased ADReCS
Blood Lactate Dehydrogenase Increased ADReCS
Blood Urea Increased ADReCS
Body Temperature Increased ADReCS
Candidiasis ADReCS
Cholestasis ADReCS
Colitis ADReCS
Convulsion ADReCS
Coombs Direct Test Positive ADReCS
Dermatitis ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Eosinophilia ADReCS
Erythema ADReCS
Erythema Multiforme ADReCS
Gastrointestinal Pain ADReCS
Haemoglobin ADReCS
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Hepatic Function Abnormal ADReCS
Hiccup MetaADEDB
Hypersensitivity ADReCS
Injection Site Phlebitis ADReCS
Kidney Diseases MetaADEDB
Leukopenia ADReCS
Nausea ADReCS
Necrolysis Epidermal SIDER
Nephritis Interstitial MetaADEDB
Nephropathy ADReCS
Nephropathy Toxic ADReCS
Neutropenia ADReCS
Osteomyelitis MetaADEDB
Pain ADReCS
Pancytopenia ADReCS
Phlebitis ADReCS
Prothrombin Level Increased ADReCS
Prothrombin Time Prolonged ADReCS
Pruritus ADReCS
Pseudomembranous Colitis ADReCS
Pyrexia ADReCS
Rash ADReCS
Renal Disorder ADReCS
Renal Impairment ADReCS
Respiratory Insufficiency MetaADEDB
Seizures SIDER
Stevens-Johnson Syndrome ADReCS
Superinfection ADReCS
Thrombocytopenia ADReCS
Thrombocytosis ADReCS
Toxic Epidermal Necrolysis ADReCS
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vaginal Moniliasis SIDER
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Mycotic Infection ADReCS

InAADR: Drug-Protein-ADRs database