| Drug Name: | Cefoperazone (62893-19-0) |
|---|---|
| PubChem ID: | 44187 |
| SMILES: | CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O |
| InchiKey: | GCFBRXLSHGKWDP-XCGNWRKASA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents |
| Molecular Weight (dalton) | : | 645.68 |
| LogP | : | -1.112 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 13 |
| Hydrogen Bond Donor Count | : | 4 |
| Total Polar Surface Area | : | 220.26 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Warfarin (81-81-2) | Hypoprothrombinaemia | Additive | Cephalosporins with an N-methylthiotetrazole side-chain can, like the oral anticoagulants, act as vitamin K antagonists to reduce the production of some blood clotting factors. They can therefore cause bleeding on their own. | Comparison of two schedules of cefoperazone plus aztreonam in the treatment of neutropenic patients with fever |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category