InAADR

Drug Information

Drug Name: Cefepime (88040-23-7)
PubChem ID: 122130607
SMILES: C[N+]1(CCCC1)CC2=C(N3C([C@@H](C3=O)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)SC2)C(=O)[O-]
InchiKey: HVFLCNVBZFFHBT-QDDPTWBHSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents

Computed Drug Properties

Molecular Weight (dalton): 480.572
LogP: -1.2799
Ring Count: 1
Hydrogen Bond Acceptor Count: 10
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 150.04

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abnormal Faeces ADReCS
Abscess Bacterial MetaADEDB
Abscess Drainage MetaADEDB
Abscess Neck MetaADEDB
Abscess Oral MetaADEDB
Accident MetaADEDB
Acidosis MetaADEDB
Acquired Diaphragmatic Eventration MetaADEDB
Activated Partial Thromboplastin Time Prolonged ADReCS
Acute Brain Syndrome MetaADEDB
Acute Graft Versus Host Disease MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Administration Site Pain MetaADEDB
Adynamic Ileus MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Agraphia MetaADEDB
Alanine Aminotransferase Increased ADReCS
Alcoholic Cirrhosis MetaADEDB
Allergic Reaction ADReCS
Altered State Of Consciousness ADReCS
Alveolitis MetaADEDB
Amentia MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angioedema ADReCS
Angiopathy MetaADEDB
Anhidrosis MetaADEDB
Anorexia MetaADEDB
Anticonvulsant Drug Level Above Therapeutic MetaADEDB
Anxiety MetaADEDB
Aortic Aneurysm MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Calcification MetaADEDB
Aplastic Anaemia ADReCS
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Abnormal ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Aspartate Aminotransferase Increased ADReCS
Aspiration Pneumonia MetaADEDB
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrial Flutter MetaADEDB
Atrioventricular Block MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Atrophy MetaADEDB
Attempted Suicide MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Benign Gastric Neoplasm MetaADEDB
Benign Lung Neoplasm MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy MetaADEDB
Birth Defect MetaADEDB
Black Stools MetaADEDB
Bleeding Hemorrhoids MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Beta-D-Glucan Increased MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Calcium MetaADEDB
Blood Calcium Decreased ADReCS
Blood Chloride Increased MetaADEDB
Blood Creatine Phosphokinase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Abnormal ADReCS
Blood Creatinine Increased ADReCS
Blood Culture Positive MetaADEDB
Blood Lactate Dehydrogenase Increased ADReCS
Blood Ph Decreased MetaADEDB
Blood Phosphorus Abnormal ADReCS
Blood Phosphorus Decreased ADReCS
Blood Potassium Abnormal ADReCS
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased ADReCS
Blood Sodium MetaADEDB
Blood Urea Abnormal ADReCS
Blood Urea Increased ADReCS
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Graft MetaADEDB
Bone Inflammation MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Operation MetaADEDB
Bone Scan Abnormal MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Brain Hypoxia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Breast Cancer Metastatic MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Right MetaADEDB
Bunion MetaADEDB
Bunion Operation MetaADEDB
C-Reactive Protein Increased MetaADEDB
Ca++ Increased SIDER
Calcium Low SIDER
Calcium Metabolism Disorder ADReCS
Candida Infection MetaADEDB
Candidiasis ADReCS
Cardiac Aneurysm MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Carotid Artery Aneurysm MetaADEDB
Carpal Tunnel MetaADEDB
Catheter Sepsis MetaADEDB
Catheter Site Haemorrhage MetaADEDB
Central Nervous System Infection MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Ischaemia MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Ischaemia MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Cholestasis ADReCS
Choriomeningitis Lymphocytic MetaADEDB
Chronic Hepatic Failure MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cmv Infection MetaADEDB
Coagulation Test Abnormal MetaADEDB
Colitis ADReCS
Colon Adenoma MetaADEDB
Colonoscopy MetaADEDB
Colpitis MetaADEDB
Coma ADReCS
Compression Fracture MetaADEDB
Computerised Tomogram MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coombs Direct Test Positive ADReCS
Coombs Test Positive ADReCS
Cryptococcosis MetaADEDB
Csf Pressure Increased MetaADEDB
Cushingoid MetaADEDB
Cyanosis MetaADEDB
Cytomegalovirus Hepatitis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Death MetaADEDB
Debridement MetaADEDB
Decreased Interest MetaADEDB
Decubitus Ulcer MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dental Implantation MetaADEDB
Dental Operation MetaADEDB
Depressed Level Of Consciousness ADReCS
Depressive Symptom MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Device Failure MetaADEDB
Device Related Infection MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Disability ADReCS
Disease Of Liver MetaADEDB
Disorder Lung MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Administration Error MetaADEDB
Drug Detoxification MetaADEDB
Drug Fever ADReCS
Dry Eye MetaADEDB
Dry Gangrene MetaADEDB
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Economic Problem MetaADEDB
Ejection Fraction Decreased MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Emotional Distress MetaADEDB
Emphysema MetaADEDB
Encephalitis MetaADEDB
Encephalopathy ADReCS
Endoscopy MetaADEDB
Endotracheal Intubation MetaADEDB
Enlarged Liver MetaADEDB
Enterobacter Pneumonia MetaADEDB
Enterococcal Infection MetaADEDB
Enterococcal Sepsis MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count ADReCS
Eosinophilia ADReCS
Epistaxis MetaADEDB
Erosive Gastritis MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Exophthalmos MetaADEDB
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Face Oedema ADReCS
Failure To Thrive MetaADEDB
Fat Tissue Increased MetaADEDB
Febrile Neutropenia ADReCS
Feeding Disorder MetaADEDB
Feeding Tube Complication MetaADEDB
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Feeling Of Despair MetaADEDB
Flatulence ADReCS
Foot Fracture MetaADEDB
Fungaemia MetaADEDB
Fungal Sepsis MetaADEDB
Gangrene MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastrointestinal Arteriovenous Malformation MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Hypomotility MetaADEDB
Gastrointestinal Pain ADReCS
Gastrointestinal Symptom Nos SIDER
Gingival Disorder MetaADEDB
Gingival Erosion MetaADEDB
Gingival Infection MetaADEDB
Gingival Oedema MetaADEDB
Granulocytosis MetaADEDB
Haematemesis MetaADEDB
Haematochezia MetaADEDB
Haematocrit Abnormal ADReCS
Haematoma MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemoglobin ADReCS
Haemolysis ADReCS
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Haemorrhage Rectum MetaADEDB
Haemorrhagic Disorder MetaADEDB
Hallucination ADReCS
Hallucinations Mixed MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Hematoma Subdural MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Impairment ADReCS
Hepatic Neoplasia MetaADEDB
Hepatitis ADReCS
Hepatitis Fulminant MetaADEDB
Hernia Hiatal MetaADEDB
High Blood Pressure MetaADEDB
Hyperaesthesia MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperbilirubinaemia ADReCS
Hypercalcaemia ADReCS
Hypercoagulation MetaADEDB
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypocalcaemia ADReCS
Hypokalaemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypophagia MetaADEDB
Hypospadias MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Iliac Artery Stenosis MetaADEDB
Impaired Healing MetaADEDB
Incisional Hernia Obstructive MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Infection Viral MetaADEDB
Inflammation ADReCS
Infusion Site Extravasation MetaADEDB
Injection Site Inflammation ADReCS
Insufficiency Renal SIDER
Intentional Self-Injury MetaADEDB
Intercostal Retraction MetaADEDB
Intermittent Claudication MetaADEDB
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Ischaemic Hepatitis MetaADEDB
Jaundice ADReCS
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Joint Injury MetaADEDB
Joint Surgery MetaADEDB
Kidney Failure MetaADEDB
Klebsiella Infection MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Large Intestinal Ulcer MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leucopenia MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Life Expectancy Shortened MetaADEDB
Liver Disorder ADReCS
Local Reaction ADReCS
Local Swelling MetaADEDB
Localised Infection MetaADEDB
Loose Tooth MetaADEDB
Loss Of Weight MetaADEDB
Lumbar Radiculopathy MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lung Edema MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm MetaADEDB
Lyell MetaADEDB
Lymph Nodes Scan Abnormal MetaADEDB
Lymphocyte Percentage MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphoid Tissue Hyperplasia MetaADEDB
Malnourished MetaADEDB
Mean Cell Haemoglobin MetaADEDB
Meningitides MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metabolic Syndrome MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metatarsalgia MetaADEDB
Mucormycosis MetaADEDB
Mucosal Inflammation MetaADEDB
Multi-Organ Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Injuries MetaADEDB
Muscle Hypertrophy MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Myoclonus ADReCS
Nasal Sinus Congestion MetaADEDB
Nausea ADReCS
Necrolysis Epidermal SIDER
Nephrolithiasis MetaADEDB
Nephropathy ADReCS
Nephropathy Toxic ADReCS
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
Neurotoxicity ADReCS
Neutropenia ADReCS
Neutrophil Count Abnormal ADReCS
Neutrophil Count Decreased MetaADEDB
Nonconvulsive Status Epilepticus SIDER
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Nuclear Magnetic Resonance Imaging Brain Abnormal MetaADEDB
Obstruction MetaADEDB
Oral Candidiasis ADReCS
Oral Disorder MetaADEDB
Oral Surgery MetaADEDB
Orbital Infection MetaADEDB
Organising Pneumonia MetaADEDB
Osteoarthritis MetaADEDB
Osteolysis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosclerosis MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pancytopenia ADReCS
Papillary Muscle Disorder MetaADEDB
Paraesthesia ADReCS
Parophthalmia MetaADEDB
Performance Status Decreased MetaADEDB
Peripheral Ischaemia MetaADEDB
Peritonitis MetaADEDB
Petechia MetaADEDB
Phlebitis ADReCS
Phlebothrombosis MetaADEDB
Phosphatase Alkaline Increased SIDER
Phosphorus Low SIDER
Phrenic Nerve Paralysis MetaADEDB
Platelet Count MetaADEDB
Platelet Disorder ADReCS
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Klebsiella MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumothorax MetaADEDB
Postrenal Failure MetaADEDB
Potassium Increased SIDER
Productive Cough MetaADEDB
Prothrombin Level Increased ADReCS
Prothrombin Time Abnormal ADReCS
Prothrombin Time Prolonged ADReCS
Pruritus ADReCS
Pruritus Genital ADReCS
Pseudomembranous Colitis ADReCS
Pseudomonas Infection MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Mass MetaADEDB
Pulmonary Radiation Injury MetaADEDB
Pyrexia ADReCS
Radius Fracture MetaADEDB
Rash ADReCS
Renal Disorder ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment ADReCS
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Reticulocyte Count Increased MetaADEDB
Retroperitoneal Neoplasm MetaADEDB
Rhonchi MetaADEDB
Road Traffic Accident MetaADEDB
Scar MetaADEDB
Seizures SIDER
Sensory Disturbance MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Serratia Bacteraemia MetaADEDB
Serratia Infection MetaADEDB
Serratia Sepsis MetaADEDB
Serum Sickness-Like Reaction ADReCS
Sinus Headache MetaADEDB
Sinus Operation MetaADEDB
Sinusitis MetaADEDB
Skin Discolouration MetaADEDB
Skin Lesion MetaADEDB
Skin Necrosis MetaADEDB
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Speech Disorder MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Deformity MetaADEDB
Spinal Disorder MetaADEDB
Spinal Fusion Surgery MetaADEDB
Spinal Osteoarthritis MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Stasis Dermatitis MetaADEDB
Status Epilepticus ADReCS
Status Epilepticus Grand Mal SIDER
Stem Cell Transplant MetaADEDB
Stenotrophomonas Infection MetaADEDB
Stent Placement MetaADEDB
Stevens-Johnson Syndrome ADReCS
Streptococcal Infection MetaADEDB
Stupor ADReCS
Subcutaneous Emphysema MetaADEDB
Sudden Death MetaADEDB
Superinfection ADReCS
Surgery MetaADEDB
Synovial Cyst MetaADEDB
Systemic Candida MetaADEDB
Tachycardia Ventricular MetaADEDB
Tearfulness MetaADEDB
Tendon Disorder MetaADEDB
Thrombocytopenia ADReCS
Tinnitus MetaADEDB
Tonsil Cancer MetaADEDB
Tooth Extraction MetaADEDB
Tooth Loss MetaADEDB
Torsade De Pointes MetaADEDB
Toxic Encephalopathy MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Tracheitis MetaADEDB
Transaminases Abnormal MetaADEDB
Troponin Increased MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urine Sodium Abnormal MetaADEDB
Urticaria ADReCS
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vaginal Moniliasis SIDER
Vascular Dementia MetaADEDB
Vascular Insufficiency MetaADEDB
Vasodilation SIDER
Vasodilation Procedure ADReCS
Venoocclusive Disease MetaADEDB
Venous Insufficiency MetaADEDB
Venous Occlusion MetaADEDB
Ventricular Fibrillation MetaADEDB
Vertebroplasty MetaADEDB
Vitamin K Deficiency MetaADEDB
Vomiting ADReCS
Vulvovaginal Candidiasis ADReCS
Vulvovaginal Mycotic Infection ADReCS
Wbc Abnormal ADReCS
Wound Drainage MetaADEDB

InAADR: Drug-Protein-ADRs database