| Drug Name: | diethylamine-NO (CASNA00015) |
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This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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| Inflammation | Tumor necrosis factor precursor (P01375) | The NO donor diethylamine-NO (DETA-NO)reduced VCAM-1 gene expression induced by the cytokine tumor necrosis factor alpha (TNF-alpha) at the cell surface level by 65% and intracellular adhesion molecule 1 (ICAM-1) gene expression by 35%,Through this mechanism, NO may function as an immunomodulator of the vessel wall and thus mediate inflammatory events involved in the pathogenesis of atherosclerosis [ ADR Type 5 ] | Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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