InAADR

Drug Information

Drug Name: Axitinib (319460-85-0)
PubChem ID: 6450551
SMILES: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4
InchiKey: RITAVMQDGBJQJZ-FMIVXFBMSA-N
Therapeutic Category: Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 386.48
LogP: 4.6391
Ring Count: 4
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 70.67

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Alanine Aminotransferase Increased ADReCS
Alopecia ADReCS
Amylase Increased PROTECT
Anaemia ADReCS
Anal Fistula PROTECT
Arthralgia ADReCS
Aspartate Aminotransferase Abnormal ADReCS
Aspartate Aminotransferase Increased ADReCS
Asthenia ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Amylase Increased ADReCS
Blood Bicarbonate Decreased ADReCS
Blood Bilirubin Increased PROTECT
Blood Creatinine Increased ADReCS
Blood Thyroid Stimulating Hormone Increased PROTECT
Cd4 Lymphocytes Decreased ADReCS
Cerebral Haemorrhage PROTECT
Cerebrovascular Accident PROTECT
Constipation ADReCS
Cough ADReCS
Decreased Appetite ADReCS
Deep Vein Thrombosis ADReCS
Dehydration ADReCS
Diarrhoea ADReCS
Dizziness ADReCS
Dry Skin ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dysphonia ADReCS
Dyspnoea ADReCS
Embolism Arterial PROTECT
Embolism Venous PROTECT
Epistaxis ADReCS
Erythema ADReCS
Fatigue ADReCS
Flatulence PROTECT
Gastric Haemorrhage PROTECT
Gastrointestinal Perforation PROTECT
Gingival Bleeding PROTECT
Haematuria ADReCS
Haemoglobin Decreased ADReCS
Haemoptysis ADReCS
Haemorrhage PROTECT
Haemorrhoids ADReCS
Headache ADReCS
Hypercalcaemia PROTECT
Hyperglycaemia ADReCS
Hyperkalaemia ADReCS
Hypernatraemia ADReCS
Hypertension ADReCS
Hypertensive Crisis PROTECT
Hyperthyroidism PROTECT
Hypoalbuminaemia ADReCS
Hypocalcaemia ADReCS
Hypoglycaemia ADReCS
Hyponatraemia ADReCS
Hypophosphataemia ADReCS
Hypothyroidism ADReCS
Leukopenia PROTECT
Lipase Increased ADReCS
Lower Gastrointestinal Haemorrhage PROTECT
Mucosal Inflammation ADReCS
Myalgia ADReCS
Myocardial Infarction PROTECT
Nausea ADReCS
Neutropenia PROTECT
Oropharyngeal Pain PROTECT
Pain In Extremity ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome ADReCS
Platelet Count Decreased ADReCS
Polycythaemia ADReCS
Posterior Reversible Encephalopathy Syndrome PROTECT
Proteinuria ADReCS
Pruritus ADReCS
Pulmonary Embolism ADReCS
Rash ADReCS
Rectal Haemorrhage ADReCS
Renal Failure PROTECT
Renal Failure Acute PROTECT
Retinal Vein Occlusion PROTECT
Retinal Vein Thrombosis PROTECT
Reversible Posterior Leukoencephalopathy Syndrome ADReCS
Stomatitis ADReCS
Thrombocytopenia PROTECT
Tinnitus ADReCS
Transient Ischaemic Attack ADReCS
Vomiting ADReCS
Weight Decreased ADReCS

InAADR: Drug-Protein-ADRs database