| Drug Name: | Aminoglutethimide (125-84-8) |
|---|---|
| PubChem ID: | 2145 |
| SMILES: | CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N |
| InchiKey: | ROBVIMPUHSLWNV-UHFFFAOYSA-N |
| Therapeutic Category: | Antineoplastic Agents, Aromatase Inhibitors, Enzyme Inhibitors, Estrogen Antagonists, Hormone Antagonists, Hormones |
| Molecular Weight (dalton) | : | 232.283 |
| LogP | : | 1.3532 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 72.19 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Cardiovascular Disease | Adenylate kinase (P00568) | Total suppression of aromatase by Cytadren may have adverse effects of cardiovascular disease [ ADR Type 1 ] | Aromatase inhibitors as potential cancer chemopreventives |
| Osteoporosis | Adenylate kinase (P00568) | Total suppression of aromatase by Cytadren may have adverse effects of increased osteoporosis. [ ADR Type 1 ] | Aromatase inhibitors as potential cancer chemopreventives |
| Urogenital Atrophy | Adenylate kinase (P00568) | Total suppression of aromatase by Cytadren may have adverse effects of urogenital atrophy [ ADR Type 1 ] | Aromatase inhibitors as potential cancer chemopreventives |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category