InAADR

Drug Information

Drug Name: Alfentanil (71195-58-9)
PubChem ID: 51263
SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC
InchiKey: IDBPHNDTYPBSNI-UHFFFAOYSA-N
Therapeutic Category: Analgesics, Anesthetics, Central Nervous System Agents, Central Nervous System Depressants, Narcotics, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 416.526
LogP: 1.3839
Ring Count: 2
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 85.49

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Reserpine (50-55-5) Ventricular Arrhythmia Antagonistic Not Understood Ventricular dysrhythmias following an alfentanil anesthetic in a patient on reserpine for hypertension

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference
Grapefruit Juice Respiratory Depression Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abnormal Lfts MetaADEDB
Abortion Induced MetaADEDB
Accidental Overdose MetaADEDB
Acidosis Respiratory MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Coronary Syndrome MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenocarcinoma MetaADEDB
Afib MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Agraphia MetaADEDB
Airway Complication Of Anaesthesia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergies MetaADEDB
Alopecia Universalis MetaADEDB
Anaesthetic Complication MetaADEDB
Anaesthetic Complication Pulmonary MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anaphylactoid Syndrome Of Pregnancy MetaADEDB
Angioedema MetaADEDB
Anoxia MetaADEDB
Anticholinergic Syndrome MetaADEDB
Antinuclear Antibody MetaADEDB
Apallic Syndrome MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Arrhythmia ADReCS
Arrhythmias Cardiac MetaADEDB
Arterial Thrombosis MetaADEDB
Ascites Infection MetaADEDB
Asthmatic Crisis MetaADEDB
Atrial Tachycardia MetaADEDB
Back Ache MetaADEDB
Base Excess MetaADEDB
Bladder Inflammation MetaADEDB
Bleb MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Triglycerides Increased MetaADEDB
Bradycardia ADReCS
Brain Death MetaADEDB
Brain Oedema MetaADEDB
Bronchospasm ADReCS
C-Reactive Protein Increased MetaADEDB
Caesarean Section MetaADEDB
Carbon Dioxide Increased ADReCS
Carbon Monoxide Diffusing Capacity Decreased MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Arrest ADReCS
Catatonia MetaADEDB
Cerebral Ischaemia MetaADEDB
Chest Discomfort ADReCS
Chest Pain MetaADEDB
Chills ADReCS
Cholecystectomies MetaADEDB
Chromosome Abnormality MetaADEDB
Clostridial Infection MetaADEDB
Coagulation Factor Decreased MetaADEDB
Coagulation Factor V Level Decreased MetaADEDB
Colitis MetaADEDB
Coma MetaADEDB
Confusion Postoperative ADReCS
Confusional State ADReCS
Cough MetaADEDB
Csf Pressure Increased MetaADEDB
Csf Protein MetaADEDB
Cyanosis MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deafness MetaADEDB
Disease Progression MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Effect Decreased MetaADEDB
Drug Exposure Before Pregnancy MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal MetaADEDB
Dry Skin MetaADEDB
Dysphasia MetaADEDB
Dystonia MetaADEDB
Ectopic Pregnancies MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St-T Segment Depression MetaADEDB
Encephalitis Allergic MetaADEDB
Enlarged Spleen MetaADEDB
Epilepsy MetaADEDB
Escherichia Infection MetaADEDB
Euphoric Mood ADReCS
Extensor Plantar Response MetaADEDB
Fasciculation MetaADEDB
Fatty Liver MetaADEDB
Feeling Abnormal ADReCS
Fib MetaADEDB
Foetal Malpresentation MetaADEDB
Formication MetaADEDB
Gall Bladder MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Glasgow Coma Scale MetaADEDB
Haematemesis MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Rate Increased MetaADEDB
Hellp Syndrome MetaADEDB
Hemiplegia MetaADEDB
Hepatic Failure MetaADEDB
Hepatitis Fulminant MetaADEDB
Hyperalgesia MetaADEDB
Hypercapnia ADReCS
Hyperkeratosis MetaADEDB
Hyperparathyroidism MetaADEDB
Hyperreflexia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hyperventilation MetaADEDB
Hypocoagulable State MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokalaemia MetaADEDB
Hypotension ADReCS
Hypotonia ADReCS
Hypoxia ADReCS
Ichthyosis MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Immobile MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infantile Spasms MetaADEDB
Infection MetaADEDB
Intraoperative Awareness MetaADEDB
Intraoperative Complications MetaADEDB
Ischaemic Stroke MetaADEDB
Labile Blood Pressure MetaADEDB
Laryngospasm ADReCS
Leukoencephalopathy MetaADEDB
Localised Oedema MetaADEDB
Lung Edema MetaADEDB
Lyell MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Microstomia MetaADEDB
Miosis MetaADEDB
Motor Dysfunction MetaADEDB
Movement Disorder ADReCS
Multi-Organ Failure MetaADEDB
Muscle Relaxant Therapy ADReCS
Muscle Rigidity ADReCS
Myocardial Ischemia MetaADEDB
Myoclonic Epilepsy MetaADEDB
Myoclonus ADReCS
Myotonia MetaADEDB
Nausea ADReCS
Neutrophilia MetaADEDB
No Therapeutic Response MetaADEDB
Nosocomial Infection MetaADEDB
Nystagmus Pathologic MetaADEDB
Obstructive Uropathy MetaADEDB
Operative Haemorrhage MetaADEDB
Optic Disc Edema MetaADEDB
Pain ADReCS
Pain Postoperative MetaADEDB
Palmar Erythema MetaADEDB
Pancreatic Necrosis MetaADEDB
Paranasal Sinus Hypersecretion MetaADEDB
Parkinson MetaADEDB
Pelvic Mass MetaADEDB
Piloerection MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Postoperative Respiratory Distress ADReCS
Premature Labour MetaADEDB
Premature Rupture Of Membranes MetaADEDB
Procedural Complication MetaADEDB
Prostate Cancer Metastatic MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pulmonary Function Test Decreased ADReCS
Pulmonary Vascular Disorder MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Rash Generalised MetaADEDB
Raynaud Phenomenon MetaADEDB
Renal Impairment MetaADEDB
Respiratory Depression ADReCS
Respiratory Disorder Neonatal MetaADEDB
Respiratory Insufficiency MetaADEDB
Respiratory Rate Decreased ADReCS
Resuscitation MetaADEDB
Rupture Of Spleen MetaADEDB
Scleroderma MetaADEDB
Screaming MetaADEDB
Sedation ADReCS
Seizures MetaADEDB
Shivering ADReCS
Sick Sinus Syndrome MetaADEDB
Sinus Arrest Cardiac MetaADEDB
Skin Desquamation MetaADEDB
Skin Test Positive MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Staring MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Suprapubic Catheter Insertion MetaADEDB
Tachycardia ADReCS
Tetany MetaADEDB
Thought Blocking MetaADEDB
Unconsciousness MetaADEDB
Urticaria ADReCS
Uterine Bleeding MetaADEDB
Varicose Vein Operation MetaADEDB
Ventricular Fibrillation MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database