InAADR

Drug Information

Drug Name: Albendazole (54965-21-8)
PubChem ID: 2082
SMILES: CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
InchiKey: HXHWSAZORRCQMX-UHFFFAOYSA-N
Therapeutic Category: Anthelmintics, Anti-Infective Agents, Anticestodal Agents, Antimitotic Agents, Antiparasitic Agents, Antiplatyhelmintic Agents, Antiprotozoal Agents, Mitosis Modulators, Tubulin Modulators

Computed Drug Properties

Molecular Weight (dalton): 265.338
LogP: 3.2433
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 67.01

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Phenytoin (57-41-0) Reduce Efficacy For Systemic Infections Antagonistic Phenytoin appear to induce the oxidative metabolism of albendazole by the cytochrome P450 isoenzyme CYP3A to roughly the same extent, resulting in significantly reduced levels of albendazole sulfoxide. Pharmacokinetic interaction between albendazole sulfoxide enantiomers and antiepileptic drugs in patients with neurocysticercosis

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abnormal Behaviour MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Movements MetaADEDB
Abnormal Vision MetaADEDB
Abortion MetaADEDB
Abortion Induced MetaADEDB
Accommodation Disorder MetaADEDB
Aching Muscles MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Hepatic Failure ADReCS
Acute Respiratory Failure MetaADEDB
Adverse Drug Effect MetaADEDB
Adverse Reaction MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased MetaADEDB
Alopecia ADReCS
Anaemia ADReCS
Anaesthesia MetaADEDB
Anemia Aplastic MetaADEDB
Angiitis MetaADEDB
Anti-Neutrophil Cytoplasmic Antibody Positive Vasculitis MetaADEDB
Anticholinergic Syndrome MetaADEDB
Aortic Aneurysm MetaADEDB
Aphthous Stomatitis MetaADEDB
Aplastic Anaemia ADReCS
Apnea MetaADEDB
Apoplexy MetaADEDB
Ascariasis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Asthenia MetaADEDB
Asystole MetaADEDB
Automatism MetaADEDB
Back Ache MetaADEDB
Balance Disorder MetaADEDB
Basedow Disease MetaADEDB
Belching MetaADEDB
Bile Duct Obstruction MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Biopsy Kidney MetaADEDB
Birth Defect MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Bleb MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Failure ADReCS
Bradypnoea MetaADEDB
Brain Oedema MetaADEDB
Bronchopneumonia MetaADEDB
Bruise MetaADEDB
Burn Oesophageal MetaADEDB
Calcinosis MetaADEDB
Carcinoembryonic Antigen Increased MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Murmur MetaADEDB
Choking MetaADEDB
Cholangiolitis MetaADEDB
Chorioretinitis MetaADEDB
Chromaturia MetaADEDB
Ciliophora Infections MetaADEDB
Coated Tongue MetaADEDB
Cognitive Disorder MetaADEDB
Colon Spastic MetaADEDB
Coma MetaADEDB
Confusion MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Constipation MetaADEDB
Convulsions Grand Mal MetaADEDB
Cough MetaADEDB
Crackles Lung MetaADEDB
Cryptococcosis MetaADEDB
Csf Pressure Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyanosis MetaADEDB
Cyst MetaADEDB
Cysticercosis MetaADEDB
Death MetaADEDB
Death Neonatal MetaADEDB
Delirium MetaADEDB
Delusion MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous MetaADEDB
Diffuse Alveolar Damage MetaADEDB
Disease Of Liver MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Drug Administration Error MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Duodenitis MetaADEDB
Dysphonia MetaADEDB
Early Morning Awakening MetaADEDB
Echinococciasis MetaADEDB
Echinococcosis Hepatic MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Encephalitis MetaADEDB
Enlarged Spleen MetaADEDB
Enterococcal Infection MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased MetaADEDB
Epilepsy MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Erythrosis MetaADEDB
Eye Pruritus MetaADEDB
Eye Swelling MetaADEDB
Eyes Sunken MetaADEDB
Facial Paralysis MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Feeling Of Body Temperature Change MetaADEDB
Fever MetaADEDB
Fish Diseases MetaADEDB
Flatulence MetaADEDB
Flu MetaADEDB
Foetal Growth Retardation MetaADEDB
Foetor Hepaticus ADReCS
Foreign Body Sensation In Eyes MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Ulcer Perforated MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Pain ADReCS
Giardiasis MetaADEDB
Glucose Intolerance MetaADEDB
Granulocytopenia ADReCS
Granuloma MetaADEDB
Grunting MetaADEDB
Haematemesis MetaADEDB
Haemolysis MetaADEDB
Headache ADReCS
Heart Rate Increased MetaADEDB
Helminthiasis MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Echinococciasis ADReCS
Hepatic Enzyme MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Necrosis MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatitis B Positive MetaADEDB
Hepatobiliary Disease SIDER
Hepatocellular Damage MetaADEDB
Hepatocellular Injury ADReCS
Hip Dysplasia MetaADEDB
Hookworm Infections MetaADEDB
Hypersensitivity ADReCS
Hypoaesthesia MetaADEDB
Hypovolaemic Shock MetaADEDB
Immune System Disorder SIDER
Impaired Work Ability MetaADEDB
Increased White Blood Cell Count MetaADEDB
Injury Asphyxiation MetaADEDB
Intention Tremor MetaADEDB
Intracranial Hypertension MetaADEDB
Intracranial Pressure Increased ADReCS
Kidney Transplant Rejection MetaADEDB
Klebsiella Sepsis MetaADEDB
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukopenia ADReCS
Lip Ulceration MetaADEDB
Liver Abscess MetaADEDB
Liver Disorder ADReCS
Liver Function Test Abnormal ADReCS
Lyell MetaADEDB
Lymphoma MetaADEDB
Mazzotti Reaction MetaADEDB
Mechanical Ventilation MetaADEDB
Meningeal Disorder ADReCS
Menstrual Disorder MetaADEDB
Metabolic Acidosis MetaADEDB
Mouth Pain MetaADEDB
Mouth Ulcer MetaADEDB
Mucosal Erosion MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Weakness MetaADEDB
Nail Discolouration MetaADEDB
Nausea ADReCS
Necrosis MetaADEDB
Nephroangiosclerosis MetaADEDB
Neurocysticercosis MetaADEDB
Neutropenia ADReCS
Nuchal Rigidity MetaADEDB
Ocular Icterus MetaADEDB
Odynophagia MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Onchocerciasis MetaADEDB
Optic Neuritis MetaADEDB
Oral Disorder MetaADEDB
Orbital Diseases MetaADEDB
Osteoarthritis MetaADEDB
Pain ADReCS
Pallor MetaADEDB
Palpitation MetaADEDB
Pancytopenia ADReCS
Plasmodium Falciparum Infection MetaADEDB
Polyhydramnios MetaADEDB
Polyradiculoneuropathy MetaADEDB
Portal Hypertension MetaADEDB
Premature Baby MetaADEDB
Product Quality Issue MetaADEDB
Pruritus MetaADEDB
Pruritus Generalised MetaADEDB
Pulse Pressure Decreased MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Restrictive Cardiomyopathy MetaADEDB
Rhinitis MetaADEDB
Scleral Discolouration MetaADEDB
Scratch MetaADEDB
Seizures MetaADEDB
Status Epilepticus MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stridor MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Superinfection Bacterial MetaADEDB
Tauopathies MetaADEDB
Thrombocytopenia ADReCS
Tongue Dry MetaADEDB
Transaminases Increased MetaADEDB
Ulcer MetaADEDB
Urethral Disorder SIDER
Urinary Tract Disorder SIDER
Urticaria ADReCS
Urticaria Generalised MetaADEDB
Vertigo ADReCS
Vomiting ADReCS

InAADR: Drug-Protein-ADRs database