| Drug Name: | Venlafaxine (93413-69-5) |
|---|---|
| PubChem ID: | 5656 |
| SMILES: | CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O |
| InchiKey: | PNVNVHUZROJLTJ-UHFFFAOYSA-N |
| Therapeutic Category: | Antidepressive Agents, Central Nervous System Agents, Membrane Transport Modulators, Neurotransmitter Agents, Neurotransmitter Uptake Inhibitors, Psychotropic Drugs, Serotonin Agents, Serotonin Uptake Inhibitors |
| Molecular Weight (dalton) | : | 277.408 |
| LogP | : | 3.0356 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 32.7 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Linezolid (165800-03-3) | Disorientated | Synergistic | Not fully understood | Linezolid, a monoamine oxidase inhibiting antibiotic, and antidepressants |
| Linezolid (165800-03-3) | Serotonin Syndrome | Synergistic | Not fully understood | Linezolid, a monoamine oxidase inhibiting antibiotic, and antidepressants |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Changes In Synaptic Function In The Brain | Growth factor ARC (Q9WV31) | Chronic treatment with antidepressant drugs induces Arc gene expression in specific regions across the rat forebrain@Up-regulation of Arc expression may be part of the process by which antidepressant drugs achieve long-term changes in synaptic function in the brain [ ADR Type 2 ] | Antidepressant drug treatment induces Arc gene expression in the rat brain |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category