| Drug Name: | Pseudoephedrine (90-82-4) |
|---|---|
| PubChem ID: | 7028 |
| SMILES: | C[C@@H]([C@H](C1=CC=CC=C1)O)NC |
| InchiKey: | KWGRBVOPPLSCSI-WCBMZHEXSA-N |
| Therapeutic Category: | Anti-Asthmatic Agents, Autonomic Agents, Bronchodilator Agents, Cardiovascular Agents, Nasal Decongestants, Peripheral Nervous System Agents, Respiratory System Agents, Vasoconstrictor Agents |
| Molecular Weight (dalton) | : | 165.236 |
| LogP | : | 1.3279 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 32.26 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Linezolid (165800-03-3) | Hypertension | Additive | Linezolid acts as a weak MAO-inhibitor, which allows the accumulation of some noradrenaline at adrenergic nerve endings associated with arterial blood vessels. Pseudoephidrine is indirectly- acting sympathomimetic, can release these above-normal amounts of noradrenaline resulting in blood vessel constriction and a rise in blood pressure | Linezolid: pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanolamine HCl, and dextromethorpan HBr |
| Tramadol (27203-92-5) | Ischaemic Colitis | Antagonistic | Not Clear | Probable ischemic colitis caused by pseudoephedrine with tramadol as a possible contributing factor |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category