InAADR

Drug Information

Drug Name: Tazobactam (89786-04-9)
PubChem ID: 123630
SMILES: C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
InchiKey: LPQZKKCYTLCDGQ-WEDXCCLWSA-N
Therapeutic Category: Anti-Bacterial Agents, Anti-Infective Agents, beta-Lactamase Inhibitors, Enzyme Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 300.296
LogP: -1.5232
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 122.46

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Mass MetaADEDB
Abnormal Lfts MetaADEDB
Abscess MetaADEDB
Abscess Limb MetaADEDB
Accidental Overdose MetaADEDB
Acid Fast Bacilli Infection MetaADEDB
Acidosis MetaADEDB
Actinomycosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Abdomen MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Febrile Neutrophilic Dermatosis MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myeloid Leukaemia Recurrent MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenitis MetaADEDB
Adenopathy MetaADEDB
Adhesiolysis MetaADEDB
Adrenal Haematoma MetaADEDB
Adynamic Ileus MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergic Dermatitis MetaADEDB
Allergies MetaADEDB
Alternaria Infection MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anaemia Postoperative MetaADEDB
Anaemic Hypoxia MetaADEDB
Angiodysplasia MetaADEDB
Angioedema MetaADEDB
Antibiotic Level Above Therapeutic MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anticoagulation Drug Level Above Therapeutic MetaADEDB
Antinuclear Antibody MetaADEDB
Anuria MetaADEDB
Apheresis MetaADEDB
Apolipoprotein Increased MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspergillosis MetaADEDB
Aspiration Bone Marrow MetaADEDB
Aspiration Bronchial MetaADEDB
Aspiration Pneumonia MetaADEDB
Autoimmune Disorder MetaADEDB
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Test Positive MetaADEDB
Bacterial Toxaemia MetaADEDB
Bicytopenia MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Adenoma MetaADEDB
Biliary Fibrosis MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Biopsy MetaADEDB
Bladder Dilatation MetaADEDB
Bladder Inflammation MetaADEDB
Blast Cell Count Increased MetaADEDB
Bleb MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Sodium Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Depression MetaADEDB
Bone Marrow Failure MetaADEDB
Brain Herniation MetaADEDB
Brain Oedema MetaADEDB
Bronchial Obstruction MetaADEDB
Bronchoalveolar Lavage MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Infection MetaADEDB
Candida Sepsis MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiopulmonary Failure MetaADEDB
Catheter Site Cellulitis MetaADEDB
Catheter Site Inflammation MetaADEDB
Catheterisation Venous MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cheilitis MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chill MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Lymphocytic Leukaemia Recurrent MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Cmv Infection MetaADEDB
Coagulation Factor V Level Decreased MetaADEDB
Colectomy MetaADEDB
Colitis MetaADEDB
Colitis Ischaemic MetaADEDB
Colitis Pseudomembranous MetaADEDB
Colostomy MetaADEDB
Coma MetaADEDB
Computerised Tomogram MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Conjunctival Disorder MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Convulsion MetaADEDB
Cross Sensitivity Reaction MetaADEDB
Cryptococcosis MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Csf Neutrophil Count Positive MetaADEDB
Csf Test Abnormal MetaADEDB
Culture Stool Positive MetaADEDB
Cyanosis MetaADEDB
Cystitis Escherichia MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytotoxic Oedema MetaADEDB
Decerebration MetaADEDB
Decreased Insulin Requirement MetaADEDB
Demyelination MetaADEDB
Dermatitides MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Dialysis MetaADEDB
Dilatation Atrial MetaADEDB
Disease Of Liver MetaADEDB
Disorder Lung MetaADEDB
Disorder Retinal MetaADEDB
Drug Interaction MetaADEDB
Drug Level Below Therapeutic MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Dyslalia MetaADEDB
Enamel Anomaly MetaADEDB
Encephalitis MetaADEDB
Encephalopathy MetaADEDB
Enlarged Liver MetaADEDB
Enterococcal Infection MetaADEDB
Enterococcal Sepsis MetaADEDB
Eosinophil Count Increased MetaADEDB
Epidermal Necrosis MetaADEDB
Epilepsy MetaADEDB
Epstein-Barr Virus Antibody Positive MetaADEDB
Erysipelas MetaADEDB
Erythema MetaADEDB
Escherichia Bacteraemia MetaADEDB
Escherichia Infection MetaADEDB
Escherichia Sepsis MetaADEDB
Escherichia Urinary Tract Infection MetaADEDB
Esophageal Stenosis MetaADEDB
Exfoliative Rash MetaADEDB
Extremity Contracture MetaADEDB
Extremity Necrosis MetaADEDB
Facial Palsy MetaADEDB
Factor V Deficiency MetaADEDB
Failure To Anastomose MetaADEDB
Fatty Liver MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Febrile Neutropenia MetaADEDB
Foetal Arrhythmia MetaADEDB
Foetal Growth Retardation MetaADEDB
Foetal Heart Rate MetaADEDB
Fungal Sepsis MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gammopathy MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Obstruction MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Graft Versus Host Disease MetaADEDB
Granulocytes Maturation Arrest MetaADEDB
Haematoma Infection MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemorrhage Intracranial MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Anaemia MetaADEDB
Heart Valve Incompetence MetaADEDB
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Artery Thrombosis MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Fibrosis MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis MetaADEDB
Hepatitis C MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatocellular Damage MetaADEDB
Hepatocellular Injury MetaADEDB
Hepatosplenomegaly MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Virus Infection MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Histology MetaADEDB
Human Herpesvirus 8 Infection MetaADEDB
Hyperammonaemia MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperbilirubinaemia Neonatal MetaADEDB
Hypercapnia MetaADEDB
Hyperphosphataemia MetaADEDB
Hypotonia MetaADEDB
Hypoxia MetaADEDB
Immune Reconstitution Syndrome MetaADEDB
Immunodeficiency MetaADEDB
Immunosuppressant Drug Level Decreased MetaADEDB
Impaired Healing MetaADEDB
Increased Platelet Count MetaADEDB
Infection MetaADEDB
Infusion Site Haemorrhage MetaADEDB
Intestinal Haemorrhage MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Intubation MetaADEDB
Itch MetaADEDB
Jaundice Neonatal MetaADEDB
Kidney Failure MetaADEDB
Laparotomy MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Large Intestinal Ulcer MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia Neonatal MetaADEDB
Leukoplakia MetaADEDB
Lichenoid Keratosis MetaADEDB
Lip Erosion MetaADEDB
Lipase MetaADEDB
Livedo Reticularis MetaADEDB
Liver Abscess MetaADEDB
Liver Transplant Rejection MetaADEDB
Loose Tooth MetaADEDB
Lung Edema MetaADEDB
Lung Neoplasm MetaADEDB
Lung Transplant MetaADEDB
Lyell MetaADEDB
Lymphedema MetaADEDB
Lymphocele MetaADEDB
Lymphocyte Count MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphocytic Dermatitis MetaADEDB
Lymphocytic Infiltration MetaADEDB
Lymphoproliferative Disorder MetaADEDB
Malnourished MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Megacolon MetaADEDB
Meningorrhagia MetaADEDB
Mixed Liver Injury MetaADEDB
Mononucleosis Syndrome MetaADEDB
Motor Retardation MetaADEDB
Mucosal Inflammation MetaADEDB
Mucous Membrane Disorder MetaADEDB
Mucous Stools MetaADEDB
Multi-Organ Failure MetaADEDB
Mutism MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myeloid Maturation Arrest MetaADEDB
Neonatal Cholestasis MetaADEDB
Nephropathy Toxic MetaADEDB
Neurological Decompensation MetaADEDB
Nikolsky Sign MetaADEDB
No Therapeutic Response MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Obstructive Uropathy MetaADEDB
Odynophagia MetaADEDB
Oedema Mouth MetaADEDB
Oesophagobronchial Fistula MetaADEDB
Oliguria MetaADEDB
Omentectomy MetaADEDB
Oral Mucosa Atrophy MetaADEDB
Oral Mucosa Erosion MetaADEDB
Osteolysis MetaADEDB
Osteosclerosis MetaADEDB
Overdose MetaADEDB
Pancreatic Enzymes Increased MetaADEDB
Papilloma Viral Infection MetaADEDB
Parotid Gland Enlargement MetaADEDB
Pelvic Infection MetaADEDB
Peptostreptococcus Infection MetaADEDB
Pericardial Haemorrhage MetaADEDB
Pericarditis MetaADEDB
Periodontitis MetaADEDB
Peripheral Ischaemia MetaADEDB
Peritoneal Effusion MetaADEDB
Peritoneal Lavage MetaADEDB
Peritonitis MetaADEDB
Perivascular Dermatitis MetaADEDB
Periventricular Leukomalacia MetaADEDB
Petechia MetaADEDB
Platelet Adhesiveness Abnormal MetaADEDB
Platelet Count MetaADEDB
Pleurisy MetaADEDB
Pneumonia Klebsiella MetaADEDB
Pneumothorax MetaADEDB
Po2 Abnormal MetaADEDB
Portal Hypertension MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Infection MetaADEDB
Premature Baby MetaADEDB
Primary Effusion Lymphoma MetaADEDB
Propofol Infusion Syndrome MetaADEDB
Proteus Infection MetaADEDB
Prothrombin Time MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pseudomonal Sepsis MetaADEDB
Pseudomonas Infection MetaADEDB
Psychiatric Decompensation MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Puncture Site Haemorrhage MetaADEDB
Puncture Site Infection MetaADEDB
Purulence MetaADEDB
Rash Generalised MetaADEDB
Reflux Esophagitis MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Impairment MetaADEDB
Renal Ischaemia MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Alkalosis MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Rate Increased MetaADEDB
Respiratory Syncytial Virus Infection MetaADEDB
Reticulocytosis MetaADEDB
Retrocollis MetaADEDB
Retroperitoneal Haematoma MetaADEDB
Rotavirus Test Positive MetaADEDB
Rupture Of Spleen MetaADEDB
Salmonella Sepsis MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Seroma MetaADEDB
Serratia Infection MetaADEDB
Serum Sickness MetaADEDB
Sinus Bradycardia MetaADEDB
Skin Desquamation MetaADEDB
Skin Necrosis MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Small Intestinal Obstruction MetaADEDB
Soft Tissue Infection MetaADEDB
Spinal X-Ray MetaADEDB
Splenectomy MetaADEDB
Splenic Haematoma MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stem Cell Transplant MetaADEDB
Stenotrophomonas Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Streptococcal Infection MetaADEDB
Subileus MetaADEDB
Surgery MetaADEDB
Surgical Procedure Repeated MetaADEDB
Systemic Mycosis MetaADEDB
Tongue Exfoliation MetaADEDB
Tonic Clonic Movements MetaADEDB
Tooth Resorption MetaADEDB
Toxic Skin Eruption MetaADEDB
Transaminases Increased MetaADEDB
Tumour Flare MetaADEDB
Tumour Lysis Syndrome MetaADEDB
Type Iv Hypersensitivity Reaction MetaADEDB
Ureteral Necrosis MetaADEDB
Ureterostomy Site Discomfort MetaADEDB
Urosepsis MetaADEDB
Urticaria Generalised MetaADEDB
Urticaria Papular MetaADEDB
Varicose Vein MetaADEDB
Venoocclusive Liver Disease MetaADEDB

InAADR: Drug-Protein-ADRs database