| Drug Name: | Penicillin v (87-08-1) |
|---|---|
| PubChem ID: | 6869 |
| SMILES: | CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C |
| InchiKey: | BPLBGHOLXOTWMN-MBNYWOFBSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 350.396 |
| LogP | : | 0.6971 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 5 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 95.94 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Depression | Glial fibrillary acidic protein (P14136) | Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for Glial fibrillary acidic protein in cortex and hippocampus [ ADR Type 1 ] | Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition |
| Depression | Proto-oncogene protein c-fos (P01100) | c-Fos protein(s) expression was high at 1 5 h and decreased at 24 h after K+ exposure and c-fos mRNA expression correlated with the immunohistochemical results, application of high K+ concentrations to a limited area of the brain surface is known to trigger spreading depression [ ADR Type 5 ] | Analysis of c-Fos and glial fibrillary acidic protein (GFAP) expression following topical application of potassium chloride (KCl) to the brain surface |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category