| Drug Name: | Amodiaquine (86-42-0) |
|---|---|
| PubChem ID: | 2165 |
| SMILES: | CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O |
| InchiKey: | OVCDSSHSILBFBN-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 355.869 |
| LogP | : | 5.1792 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 48.39 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Hepatotoxicity | Myeloperoxidase precursor (P05164) | Associated with idiosyncratic hepatotoxicity [ ADR Type 2 ] | Myeloperoxidase as a generator of drug free radicals |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|---|---|---|---|
| Iminoquinone | Agranulocytosis | Deleterious effects of reactive metabolites | ||
| Iminoquinone | Hepatotoxicity | Deleterious effects of reactive metabolites |
This panel provides information on drug category