InAADR

Drug Information

Drug Name: Nafamostat mesilate (82956-11-4)
PubChem ID: 5311180
SMILES: CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
InchiKey: SRXKIZXIRHMPFW-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 539.592
LogP: 1.25597
Ring Count: 3
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 6
Total Polar Surface Area: 249.31

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Abnormal Behaviour MetaADEDB
Acidosis MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Altered State Of Consciousness MetaADEDB
Amyotrophy MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Apathy MetaADEDB
Arrhythmia MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspergillosis MetaADEDB
Asystole MetaADEDB
Atrioventricular Block Second Degree MetaADEDB
Automatism MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Basedow Disease MetaADEDB
Black Stools MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Pain MetaADEDB
Bradycardia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Calculus Bladder MetaADEDB
Calculus Urinary MetaADEDB
Candida Infection MetaADEDB
Candidiasis Of Mouth MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Failure Chronic MetaADEDB
Cardiogenic Shock MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Clostridial Infection MetaADEDB
Colonic Stenosis MetaADEDB
Condition Aggravated MetaADEDB
Convulsion MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Diabetes Insipidus MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Early Morning Awakening MetaADEDB
Eating Disorder MetaADEDB
Encephalitis Allergic MetaADEDB
Enterocolitis MetaADEDB
Epidermolysis MetaADEDB
Epistaxis MetaADEDB
Excess Potassium MetaADEDB
Extrasystoles MetaADEDB
Extrasystoles Ventricular MetaADEDB
Fibrin D Dimer MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastrointestinal Hypomotility MetaADEDB
Haemodialysis MetaADEDB
Hemothorax MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Fulminant MetaADEDB
Incorrect Route Of Drug Administration MetaADEDB
Increased White Blood Cell Count MetaADEDB
Kidney Failure MetaADEDB
Klebsiella Infection MetaADEDB
Leukoencephalopathy MetaADEDB
Lip Ulceration MetaADEDB
Liver Abscess MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lung Transplant MetaADEDB
Lyell MetaADEDB
Meningitis Bacterial MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Enzyme MetaADEDB
Necrotising Fasciitis MetaADEDB
Neumonia MetaADEDB
No Therapeutic Response MetaADEDB
Oliguria MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain Of Skin MetaADEDB
Pancreatitis MetaADEDB
Phlebitis Infective MetaADEDB
Photosensitive Rash MetaADEDB
Platelet Count MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Cytomegaloviral MetaADEDB
Portal Vein Thrombosis MetaADEDB
Pre-Existing Disease MetaADEDB
Pulmonary Hypertension MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Retinal Vein Occlusion MetaADEDB
Rib Fracture MetaADEDB
Right Heart Failure MetaADEDB
Therapy Non-Responder MetaADEDB
Tumour Lysis Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database