InAADR: Drug-Protein-ADRs database

Drug Name:	colistimethate (8068-28-8)
PubChem ID:	216258
SMILES:	CCC(C)CCCCC(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCNCS(=O)(=O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)[O-])CCNCS(=O)(=O)[O-])C(C)O.[Na+].[Na+].[Na+].[Na+].[Na+]
InchiKey:	IQWHCHZFYPIVRV-UHFFFAOYSA-I
Therapeutic Category:

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug	Toxicity	Interaction Type	Mechanism	Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity	Interacting Protein	Mechanism	Reference

This panel provides drug-food interactions and their ADRs along with references

Food	Toxicity	Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite	Toxicity	Place of Metabolism	Mechanism	Reference

This panel provides information on drug category

Toxicity	Source
Abdominal Discomfort	ADReCS
Apnoea	ADReCS
Blood Creatinine Increased	ADReCS
Blood Urea Nitrogen Increased	ADReCS
Creatinine Renal Clearance Decreased	ADReCS
Dizziness	ADReCS
Dysarthria	ADReCS
Forced Expiratory Volume Decreased	PROTECT
Increased Upper Airway Secretion	PROTECT
Medication Error	PROTECT
Nephropathy Toxic	ADReCS
Paraesthesia	ADReCS
Paraesthesia Oral	ADReCS
Pruritus	ADReCS
Pyrexia	ADReCS
Rash	ADReCS
Respiratory Distress	ADReCS
Urine Output Decreased	ADReCS
Urticaria	ADReCS
Vertigo	ADReCS

Molecular Weight (dalton)	:	1749.84
LogP	:	-24.7534
Ring Count	:	0
Hydrogen Bond Acceptor Count	:	33
Hydrogen Bond Donor Count	:	18
Total Polar Surface Area	:	706.71