InAADR

Drug Information

Drug Name: Rifaximin (80621-81-4)
PubChem ID: 122361733
SMILES: C[C@H]1/C=C/C=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(OC=C[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)/C
InchiKey: NZCRJKRKKOLAOJ-OUVHNKGRSA-N
Therapeutic Category: Anti-Infective Agents, Gastrointestinal Agents

Computed Drug Properties

Molecular Weight (dalton): 785.891
LogP: 6.15784
Ring Count: 4
Hydrogen Bond Acceptor Count: 13
Hydrogen Bond Donor Count: 5
Total Polar Surface Area: 198.38

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness ADReCS
Abnormal Dreams ADReCS
Abnormal Faeces ADReCS
Acantholysis MetaADEDB
Accidental Overdose MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Afib MetaADEDB
Ageusia ADReCS
Alanine Aminotransferase MetaADEDB
Ammonia Increased MetaADEDB
Amnesia ADReCS
Amoebic Colitis MetaADEDB
Anaemia ADReCS
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Angioedema ADReCS
Angiopathy ADReCS
Anhedonia MetaADEDB
Anorectal Discomfort ADReCS
Anorexia ADReCS
Aortic Aneurysm SIDER
Aortic Calcification MetaADEDB
Aortic Dilatation MetaADEDB
Aortic Dissection SIDER
Apathy MetaADEDB
Arthralgia ADReCS
Ascites ADReCS
Aspartate Aminotransferase Increased ADReCS
Asterixis MetaADEDB
Asthenia ADReCS
Asystole MetaADEDB
Ataxia MetaADEDB
Atrophy MetaADEDB
Av Dissociation MetaADEDB
Back Ache MetaADEDB
Back Pain ADReCS
Bacteria Stool Identified MetaADEDB
Bacterial Toxaemia MetaADEDB
Bile Duct Obstruction MetaADEDB
Birth Defect MetaADEDB
Bleeding Gums MetaADEDB
Bleeding Vaginal MetaADEDB
Blood Glucose Fluctuation MetaADEDB
Blood In Stool SIDER
Blood Iron Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Blood Urine ADReCS
Blood Urine Present ADReCS
Body Temperature Increased MetaADEDB
Bone Disorder ADReCS
Bone Marrow Failure MetaADEDB
Bone Pain MetaADEDB
Brain Oedema MetaADEDB
Breast Calcifications MetaADEDB
Breast Cancer MetaADEDB
Breast Operation MetaADEDB
Breath Sounds Abnormal MetaADEDB
Bronchiolitis MetaADEDB
Burning Sensation MetaADEDB
Cardiac Decompensation MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiopulmonary Failure MetaADEDB
Carotid Artery Stenosis MetaADEDB
Cellulitis ADReCS
Central Nervous System Inflammation MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Ischaemia MetaADEDB
Cervicalgia MetaADEDB
Chest Pain ADReCS
Choluria ADReCS
Chronic Hepatic Failure MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cirrhosis MetaADEDB
Clostridium Difficile Colitis ADReCS
Clotting MetaADEDB
Cold Sweat ADReCS
Colitis ADReCS
Colitis Collagenous MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Constipation ADReCS
Contusion ADReCS
Cough ADReCS
Crohn Disease MetaADEDB
Csf Pressure Increased MetaADEDB
Culture Positive MetaADEDB
Cyst MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer MetaADEDB
Defaecation Urgency ADReCS
Deglutition Disorder MetaADEDB
Dehydration ADReCS
Dental Abscess MetaADEDB
Dental Pain MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Atopic ADReCS
Dermatitis Exfoliative ADReCS
Dermatosis MetaADEDB
Dermographism MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Neuropathy MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disturbance In Attention ADReCS
Dizziness ADReCS
Drug Dispensing Error MetaADEDB
Drug Ineffective MetaADEDB
Drug Prescribing Error MetaADEDB
Dry Mouth ADReCS
Dry Throat ADReCS
Dysentery ADReCS
Dysphagia ADReCS
Dysphonia MetaADEDB
Dyspnoea ADReCS
Dysuria ADReCS
Ear Pain ADReCS
Early Morning Awakening MetaADEDB
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalopathy MetaADEDB
Endodontic Procedure MetaADEDB
Enlarged Spleen MetaADEDB
Enteritis MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epistaxis ADReCS
Excess Potassium MetaADEDB
Excoriation MetaADEDB
Extremity Pain MetaADEDB
Eyelid Retraction MetaADEDB
Facial Palsy MetaADEDB
Faecal Incontinence MetaADEDB
Fall ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Fibromyalgia MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Flushing ADReCS
Fungal Disease MetaADEDB
Gastric Disorder ADReCS
Gastroenteritis Viral MetaADEDB
Gastrointestinal Disorder SIDER
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Pain ADReCS
Generalised Oedema ADReCS
Gingival Disorder ADReCS
Granulocytosis MetaADEDB
Haematochezia ADReCS
Haematuria ADReCS
Haemolytic Anaemia MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Hematoma Subdural MetaADEDB
Hepatic Calcification MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatitis C MetaADEDB
Hepatorenal Failure MetaADEDB
Hepatotoxicity MetaADEDB
Hernia ADReCS
High Frequency Ablation MetaADEDB
Hot Flush ADReCS
Hyperglycaemia ADReCS
Hyperglycaemic Hyperosmolar Nonketotic Syndrome MetaADEDB
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hypersensitivity ADReCS
Hypertonia MetaADEDB
Hypoaesthesia ADReCS
Hypoalbuminaemia MetaADEDB
Hypoglycaemia ADReCS
Hypokalaemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hyponatraemia ADReCS
Hypophagia MetaADEDB
Hypotension ADReCS
Ill-Defined Disorder ADReCS
Impetigo MetaADEDB
Infection ADReCS
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza Like Illness ADReCS
Inguinal Hernia ADReCS
Injection Site Erythema MetaADEDB
Insomnia ADReCS
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
International Normalised Ratio Fluctuation MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Disc Disorder MetaADEDB
Itch MetaADEDB
Joint Stiffness MetaADEDB
Kidney Failure MetaADEDB
Large Intestine Perforation MetaADEDB
Lethargy MetaADEDB
Lip Dry ADReCS
Localised Oedema MetaADEDB
Loss Of Consciousness ADReCS
Lower Gastrointestinal Haemorrhage MetaADEDB
Lung Edema MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphocytosis ADReCS
Malaise ADReCS
Mediastinal Disorder SIDER
Megacolon MetaADEDB
Memory Impairment ADReCS
Menopausal Symptoms ADReCS
Mental Disorder SIDER
Metastases To Liver MetaADEDB
Metastases To Spine MetaADEDB
Micturition Urgency MetaADEDB
Migraine ADReCS
Monocytosis ADReCS
Motion Sickness ADReCS
Mouth Pain MetaADEDB
Muscle Inflammation MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain MetaADEDB
Myalgia ADReCS
Nasal Discomfort MetaADEDB
Nasal Disorder MetaADEDB
Nasal Dryness MetaADEDB
Nasal Irrigation ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Pain ADReCS
Nervous System Disorder SIDER
Neutropenia ADReCS
No Therapeutic Response MetaADEDB
Nodule MetaADEDB
Nodule On Extremity MetaADEDB
Ocular Icterus MetaADEDB
Oedema ADReCS
Oesophageal Varices Haemorrhage ADReCS
Oropharyngeal Pain ADReCS
Osteosclerosis MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pain Pelvic MetaADEDB
Pancreatic Necrosis MetaADEDB
Paracentesis MetaADEDB
Perineal Abscess MetaADEDB
Periorbital Oedema ADReCS
Peritonitis MetaADEDB
Peritonitis Bacterial MetaADEDB
Petechia MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngitis ADReCS
Pharyngitis Streptococcal MetaADEDB
Pharyngolaryngeal Pain SIDER
Pneumonia ADReCS
Pollakiuria ADReCS
Polyuria ADReCS
Poor Quality Sleep MetaADEDB
Procedural Pain ADReCS
Proctalgia ADReCS
Protein Urine Present ADReCS
Proteinuria ADReCS
Pruritus ADReCS
Psoriasis MetaADEDB
Pulmonary Toxicity MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Rectal Tenesmus ADReCS
Rectal Ulcer Haemorrhage MetaADEDB
Respiratory Tract Infection ADReCS
Rhinitis ADReCS
Rhinorrhea MetaADEDB
Rhinorrhoea ADReCS
Scab MetaADEDB
Scotoma MetaADEDB
Shock ADReCS
Shock Haemorrhagic MetaADEDB
Short-Bowel Syndrome MetaADEDB
Sickness SIDER
Sinus Bradycardia MetaADEDB
Skin Haemorrhage MetaADEDB
Specific Gravity Urine Increased MetaADEDB
Spinning Sensation MetaADEDB
Splenic Infarction MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Sticky Skin ADReCS
Stomach Discomfort ADReCS
Streptococcal Infection MetaADEDB
Stress MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Sunburn ADReCS
Sweating SIDER
Sweating Increased SIDER
Swelling ADReCS
Swelling Face ADReCS
Syncope ADReCS
Tinnitus ADReCS
Tongue Discolouration MetaADEDB
Tooth Discolouration MetaADEDB
Tooth Disease MetaADEDB
Tooth Fracture MetaADEDB
Tooth Infection MetaADEDB
Tooth Repair MetaADEDB
Transfusion Reaction MetaADEDB
Tremor ADReCS
Type Iv Hypersensitivity Reaction MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upset Stomach SIDER
Urethral Disorder SIDER
Urinary Tract Disorder SIDER
Urinary Tract Infection Fungal MetaADEDB
Urinary Tract Infection Staphylococcal MetaADEDB
Urine Output Increased ADReCS
Urticaria ADReCS
Vascular Calcification MetaADEDB
Vascular Cauterisation MetaADEDB
Vertigo ADReCS
Vomiting ADReCS
Vulvovaginal Mycotic Infection MetaADEDB
Weakness SIDER
Weight Decreased ADReCS
Weight Increased ADReCS
Wrong Drug Administered MetaADEDB

InAADR: Drug-Protein-ADRs database