InAADR

Drug Information

Drug Name: Epinastine (80012-43-7)
PubChem ID: 3241
SMILES: C1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N
InchiKey: WHWZLSFABNNENI-UHFFFAOYSA-N
Therapeutic Category: Histamine Agents, Histamine Antagonists, Histamine H1 Antagonists, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 249.317
LogP: 2.4668
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 41.62

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Symptom MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Behaviour MetaADEDB
Abortion MetaADEDB
Accelerated Hypertension MetaADEDB
Aching Muscles MetaADEDB
Acid Fast Bacilli Infection MetaADEDB
Acidosis MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Adenocarcinoma MetaADEDB
Adrenal Suppression MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergic Cystitis MetaADEDB
Allergic Dermatitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Amyotrophy MetaADEDB
Anaesthesia MetaADEDB
Anemia Aplastic MetaADEDB
Angiitis MetaADEDB
Angiosarcoma MetaADEDB
Anorexia MetaADEDB
Anti-Insulin Antibody MetaADEDB
Aortic Regurgitation MetaADEDB
Apathy MetaADEDB
Areflexia MetaADEDB
Arthritis Rheumatoid MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asteatosis MetaADEDB
Asthma MetaADEDB
Automatism MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Toxaemia MetaADEDB
Bence Jones Protein Urine MetaADEDB
Biliary Anastomosis MetaADEDB
Biliary Fibrosis MetaADEDB
Biloma MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Gums MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Bilirubin MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Bilirubin Unconjugated Increased MetaADEDB
Blood Cholesterol Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Lactate Dehydrogenase Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Thyroid Stimulating Hormone MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature Increased MetaADEDB
Brain Stem Haemorrhage MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Cancer Recurrent MetaADEDB
Bronchial Wall Thickening MetaADEDB
Bronchostenosis MetaADEDB
Brugada Syndrome MetaADEDB
Burning Sensation ADReCS
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cancer Pain MetaADEDB
Carcinoembryonic Antigen Increased MetaADEDB
Carcinoma Of The Cervix MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Function Test Abnormal MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardiomyopathy MetaADEDB
Cardiovascular Disorder MetaADEDB
Cartilage Development Disorder MetaADEDB
Catheterisation Cardiac MetaADEDB
Cellulitis Staphylococcal MetaADEDB
Central Nervous System Lesion MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Cervicalgia MetaADEDB
Cheilitis MetaADEDB
Chill MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Cognitive Disorder MetaADEDB
Cold Symptoms SIDER
Colitis Ischaemic MetaADEDB
Colorectal Cancer MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Conjunctivitis ADReCS
Conversion Disorder MetaADEDB
Cough ADReCS
Cough Increased ADReCS
Csf Monocyte Count Decreased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Dermographism MetaADEDB
Device Related Infection MetaADEDB
Diarrhea MetaADEDB
Disease Of Liver MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Drug Abuser MetaADEDB
Drug Exposure Before Pregnancy MetaADEDB
Duodenal Ulcer Haemorrhage MetaADEDB
Dyslalia MetaADEDB
Dyspnea Exertional MetaADEDB
Dysstasia MetaADEDB
Echocardiogram Abnormal MetaADEDB
Eczema MetaADEDB
Educational Problem MetaADEDB
Electrocardiogram T Wave Abnormal MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Elevated Mood MetaADEDB
Encephalitis MetaADEDB
Endotracheal Intubation MetaADEDB
Enterocolitis MetaADEDB
Enterocolitis Bacterial MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epidermolysis MetaADEDB
Epilepsy MetaADEDB
Erythema MetaADEDB
Erythema Multiforme MetaADEDB
Escherichia Infection MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Irritation ADReCS
Eye Luxation MetaADEDB
Eye Pruritus MetaADEDB
Facial Palsy MetaADEDB
Feeding Tube Complication MetaADEDB
Feeling Abnormal MetaADEDB
Feeling Drunk MetaADEDB
Flu MetaADEDB
Fluid Intake Reduced MetaADEDB
Folliculitis ADReCS
Galactorrhea MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Erosion MetaADEDB
Gastrointestinal Hypomotility MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Glaucoma MetaADEDB
Glomerulonephritis Proliferative MetaADEDB
Glucose Urine MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Granulocyte Count Decreased MetaADEDB
Haemodialysis MetaADEDB
Haemophilus Infection MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Headache ADReCS
Helicobacter Infection MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatocellular Injury MetaADEDB
Hernia Inguinal MetaADEDB
Herpes Zoster MetaADEDB
Hilar Lymphadenopathy MetaADEDB
Humerus Fracture MetaADEDB
Hyperaemia ADReCS
Hyperammonaemia MetaADEDB
Hypoaesthesia Oral MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hyporeflexia MetaADEDB
Ild MetaADEDB
Incontinence MetaADEDB
Increased Appetite MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection ADReCS
Infusion Related Reaction MetaADEDB
Injection Site Ulcer MetaADEDB
Intervertebral Discitis MetaADEDB
Intraocular Lens Dislocation MetaADEDB
Iron Binding Capacity Unsaturated Decreased MetaADEDB
Irritation Skin MetaADEDB
Itch MetaADEDB
Jra MetaADEDB
Keratoconus MetaADEDB
Lacrimation SIDER
Lacrimation Increased ADReCS
Lacunar Infarction MetaADEDB
Large Intestinal Ulcer MetaADEDB
Laryngeal Haemorrhage MetaADEDB
Laryngeal Inflammation MetaADEDB
Laryngotracheo Bronchitis MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Left Ventricular End-Diastolic Pressure Decreased MetaADEDB
Leukopenia Neonatal MetaADEDB
Limb Discomfort MetaADEDB
Liver Abscess MetaADEDB
Low Density Lipoprotein Decreased MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration MetaADEDB
Lupus Nephritis MetaADEDB
Lupus-Like Syndrome MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Mean Cell Haemoglobin Decreased MetaADEDB
Mean Cell Volume Decreased MetaADEDB
Mechanical Ventilation MetaADEDB
Meningitis Noninfective MetaADEDB
Menstrual Disorder MetaADEDB
Metabolic Encephalopathy MetaADEDB
Micturition Disorder MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Musculoskeletal Pain MetaADEDB
Nasopharyngitis ADReCS
Neoplasia MetaADEDB
Neurogenic Bladder MetaADEDB
Neurosis MetaADEDB
Neutropenic Infection MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nocturnal Dyspnoea MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Non-Small Cell Lung Cancer MetaADEDB
Ocular Discomfort MetaADEDB
Oliguria MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Oropharyngeal Pain MetaADEDB
Overdose MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitation MetaADEDB
Pancreatic Enzymes Increased MetaADEDB
Pancreatic Pseudocyst MetaADEDB
Parotid Gland Enlargement MetaADEDB
Pedal Pulse Absent MetaADEDB
Pericardial Drainage MetaADEDB
Pericardial Effusion MetaADEDB
Peroneal Nerve Palsy MetaADEDB
Pharyngitis ADReCS
Phlebitis Infective MetaADEDB
Photosensitive Rash MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia Streptococcal MetaADEDB
Pneumothorax MetaADEDB
Polymyositis MetaADEDB
Poriomania MetaADEDB
Procedural Pain MetaADEDB
Proteus Infection MetaADEDB
Prothrombin Level Decreased MetaADEDB
Pruritus ADReCS
Pseudomonas Infection MetaADEDB
Psoas Abscess MetaADEDB
Psychiatric Symptom MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Mass MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Pustular Psoriasis MetaADEDB
Pyloric Stenosis MetaADEDB
Rash Generalised MetaADEDB
Red Blood Cell Count Increased MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Disorder MetaADEDB
Respiratory Rate Increased MetaADEDB
Respiratory Tract Infection ADReCS
Retinal Bleeding MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retroperitoneal Abscess MetaADEDB
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis ADReCS
Right Ventricular Systolic Pressure Decreased MetaADEDB
Scrotal Disorder MetaADEDB
Scrotal Swelling MetaADEDB
Sensory Disturbance MetaADEDB
Septic Shock MetaADEDB
Serum Ferritin Increased MetaADEDB
Sinusitis ADReCS
Sjogren Syndrome MetaADEDB
Smallpox MetaADEDB
Speech Disorder MetaADEDB
Spinal Cord Injury MetaADEDB
Spondylitis MetaADEDB
Sputum Retention MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subcorneal Pustular Dermatosis MetaADEDB
Subdural Haemorrhage MetaADEDB
Subileus MetaADEDB
Syncope Vasovagal MetaADEDB
Tachycardia Ventricular MetaADEDB
Tension Headache MetaADEDB
Thalamus Haemorrhage MetaADEDB
Tooth Discolouration MetaADEDB
Tooth Hypoplasia MetaADEDB
Toxic Skin Eruption MetaADEDB
Tracheostomy MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upper Respiratory Tract Inflammation MetaADEDB
Ventricular Dyskinesia MetaADEDB
Ventricular Fibrillation MetaADEDB
Ventricular Internal Diameter Abnormal MetaADEDB
Vitreous Disorder MetaADEDB

InAADR: Drug-Protein-ADRs database