InAADR

Drug Information

Drug Name: roxatidine acetate (78628-28-1)
PubChem ID: 5105
SMILES: CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2
InchiKey: SMTZFNFIKUPEJC-UHFFFAOYSA-N
Therapeutic Category: Anti-Ulcer Agents, Gastrointestinal Agents, Histamine Agents, Histamine Antagonists, Histamine H2 Antagonists, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 348.443
LogP: 2.1207
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 67.87

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Symptom MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Febrile Neutrophilic Dermatosis MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenomatous Polyposis Coli MetaADEDB
Adnexa Uteri Mass MetaADEDB
Adynamic Ileus MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anorexia MetaADEDB
Antinuclear Antibody Increased MetaADEDB
Anuria MetaADEDB
Apathy MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Atypical Mycobacterial Infection MetaADEDB
Autoimmune Hepatitis MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Pyelonephritis MetaADEDB
Bedridden MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Retention MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Brain Barrier Defect MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Gases Abnormal MetaADEDB
Blood Immunoglobulin A Increased MetaADEDB
Blood Immunoglobulin G Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Brain Abscess MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Neoplasm MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cardiac Failure MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Catheter Site Pain MetaADEDB
Cerebral Infarct MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Chromosome Analysis Abnormal MetaADEDB
Cirrhosis MetaADEDB
Colitis Ischaemic MetaADEDB
Colorectal Cancer MetaADEDB
Concomitant Disease Progression MetaADEDB
Coughing Blood MetaADEDB
Crackles Lung MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cutaneous Tuberculosis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Deafness Congenital MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Exfoliative MetaADEDB
Dermatitis Seborrheic MetaADEDB
Disease Of Liver MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness MetaADEDB
Drowsiness MetaADEDB
Dyspepsia MetaADEDB
Dysphoria MetaADEDB
Dysstasia MetaADEDB
Endoscopy Small Intestine MetaADEDB
Eosinophil Percentage Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Epidural Abscess MetaADEDB
Escherichia Infection MetaADEDB
Eyelid Function Disorder MetaADEDB
Feeling Abnormal MetaADEDB
Femur Fracture MetaADEDB
Fibrin D Dimer MetaADEDB
Fluid Overload MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Antral Vascular Ectasia MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Ulcer MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Oedema MetaADEDB
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Genital Tract Inflammation MetaADEDB
Globulinuria MetaADEDB
Glomerulosclerosis MetaADEDB
Glucose Urine MetaADEDB
Haematemesis MetaADEDB
Haemochromatosis MetaADEDB
Haemodialysis MetaADEDB
Haemorrhagic Cerebral Infarction MetaADEDB
Haptoglobin Decreased MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis Acute MetaADEDB
Hip Arthroplasty MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Immune System Disorder MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Upper Respiratory MetaADEDB
Injury Asphyxiation MetaADEDB
Iron Deficiency Anaemia MetaADEDB
Kaposi Varicelliform Eruption MetaADEDB
Kidney Transplant Rejection MetaADEDB
Large Intestine Perforation MetaADEDB
Leukopenia Neonatal MetaADEDB
Lung Adenocarcinoma Metastatic MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Markedly Reduced Dietary Intake MetaADEDB
Mean Cell Haemoglobin MetaADEDB
Mean Cell Haemoglobin Decreased MetaADEDB
Microangiopathic Haemolytic Anaemia MetaADEDB
Miosis MetaADEDB
Muscle Disorder MetaADEDB
Muscle Inflammation MetaADEDB
Nasopharyngitis MetaADEDB
Nausea MetaADEDB
Neoplasm Prostate MetaADEDB
Nephrotic Syndrome MetaADEDB
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nutritional Condition Abnormal MetaADEDB
Oculomucocutaneous Syndrome MetaADEDB
Oliguria MetaADEDB
Osteoporosis MetaADEDB
Ovarian Cancer MetaADEDB
Pancreatic Carcinoma Recurrent MetaADEDB
Parkinson MetaADEDB
Percutaneous Coronary Intervention MetaADEDB
Pericarditis MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Polymyositis MetaADEDB
Prostatic Abscess MetaADEDB
Protein Total Decreased MetaADEDB
Pseudomonas Infection MetaADEDB
Psoriasis MetaADEDB
Pyelonephritis Acute MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Pyothorax MetaADEDB
Red Blood Cell Schistocytes Present MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Salt-Wasting Syndrome MetaADEDB
Respiratory Failure MetaADEDB
Retinal Bleeding MetaADEDB
Rhabdomyolysis MetaADEDB
Scar MetaADEDB
Scleroderma MetaADEDB
Scleroderma Renal Crisis MetaADEDB
Septic Shock MetaADEDB
Serum Ferritin Increased MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Small Intestine Ulcer MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Emphysema MetaADEDB
Surgical Procedure Repeated MetaADEDB
Tuberculosis Of Genitourinary System MetaADEDB
Tuberculous Pleurisy MetaADEDB

InAADR: Drug-Protein-ADRs database