InAADR

Drug Information

Drug Name: Nepafenac (78281-72-8)
PubChem ID: 151075
SMILES: C1=CC=C(C=C1)C(=O)C2=C(C(=CC=C2)CC(=O)N)N
InchiKey: QEFAQIPZVLVERP-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 254.289
LogP: 1.5276
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 86.18

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain MetaADEDB
Acanthamoeba Infection MetaADEDB
Accelerated Hypertension MetaADEDB
Accidental Overdose MetaADEDB
Acquired Diaphragmatic Eventration MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Alopecia MetaADEDB
Amnesia MetaADEDB
Angiomyolipoma MetaADEDB
Anhedonia MetaADEDB
Anterior Chamber Disorder MetaADEDB
Anterior Chamber Inflammation MetaADEDB
Anxiety MetaADEDB
Apathy MetaADEDB
Apraxia MetaADEDB
Aptyalism MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Asthenia MetaADEDB
Asthenopia MetaADEDB
Autoimmune Disorder MetaADEDB
Bacillus Infection MetaADEDB
Back Ache MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Blepharoptosis MetaADEDB
Blindness Unilateral MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Pressure Increased PROTECT
Blurred Vision MetaADEDB
Bruise MetaADEDB
Capillary Disorder MetaADEDB
Cataract ADReCS
Cataract Operation MetaADEDB
Chest Pain MetaADEDB
Choroidal Effusion PROTECT
Condition Aggravated MetaADEDB
Conjunctival Deposit MetaADEDB
Conjunctival Hyperaemia ADReCS
Conjunctival Oedema ADReCS
Conjunctivitis ADReCS
Conjunctivitis Allergic SIDER
Corneal Abrasion MetaADEDB
Corneal Clouding MetaADEDB
Corneal Deposits ADReCS
Corneal Epithelium Defect PROTECT
Corneal Epithelium Disorder MetaADEDB
Corneal Erosion MetaADEDB
Corneal Infection MetaADEDB
Corneal Infiltrates MetaADEDB
Corneal Oedema ADReCS
Corneal Opacity ADReCS
Corneal Scar ADReCS
Corneal Thinning MetaADEDB
Corneal Ulcer MetaADEDB
Cough MetaADEDB
Culture Positive MetaADEDB
Cutis Laxa PROTECT
Dehydration MetaADEDB
Dental Caries MetaADEDB
Detachment Psychological SIDER
Discomfort ADReCS
Dislocation MetaADEDB
Disorder Of Globe MetaADEDB
Dissociation ADReCS
Dizziness PROTECT
Dizziness Exertional MetaADEDB
Drug Toxicity MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Eye ADReCS
Dry Mouth ADReCS
Economic Problem MetaADEDB
Effusion ADReCS
Erythema Migrans MetaADEDB
Erythema Of Eyelid MetaADEDB
Escherichia Infection MetaADEDB
Extremity Pain MetaADEDB
Eye Discharge ADReCS
Eye Disorder SIDER
Eye Infection Staphylococcal MetaADEDB
Eye Inflammation ADReCS
Eye Injury MetaADEDB
Eye Irritation ADReCS
Eye Operation MetaADEDB
Eye Pain ADReCS
Eye Pruritus ADReCS
Eye Swelling PROTECT
Eyelid Disorder ADReCS
Eyelid Margin Crusting ADReCS
Eyelids Pruritus MetaADEDB
Feeling Abnormal MetaADEDB
Foot Fracture MetaADEDB
Foreign Body Sensation In Eyes ADReCS
Gastroduodenitis MetaADEDB
Gastrointestinal Disorder SIDER
Glare MetaADEDB
Glaucoma MetaADEDB
Glaucoma Surgery MetaADEDB
Globulinuria MetaADEDB
Glossitis MetaADEDB
Goiter MetaADEDB
Grip Strength MetaADEDB
Haematoma MetaADEDB
Halo Vision MetaADEDB
Headache ADReCS
Hepatic Enzyme MetaADEDB
Hepatitis MetaADEDB
High Blood Pressure MetaADEDB
Hyperaemia ADReCS
Hyperhidrosis MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia MetaADEDB
Hypoaesthesia Oral MetaADEDB
Iatrogenic Injury MetaADEDB
Immune System Disorder SIDER
Impaired Driving Ability MetaADEDB
Impaired Healing ADReCS
Increased White Blood Cell Count MetaADEDB
Infection Viral MetaADEDB
Intentional Drug Misuse MetaADEDB
Intraocular Inflammation MetaADEDB
Intraocular Lens Implant MetaADEDB
Intraocular Pressure Fluctuation MetaADEDB
Intraocular Pressure Increased ADReCS
Iritis ADReCS
Keratitis ADReCS
Laboratory Test Interference MetaADEDB
Lacrimation SIDER
Lacrimation Increased ADReCS
Lenticular Opacities ADReCS
Light Sensitivity MetaADEDB
Macular Oedema MetaADEDB
Madarosis MetaADEDB
Mean Cell Haemoglobin Increased MetaADEDB
Mucosal Dryness MetaADEDB
Multiple Injuries MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Nail Tinea MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Nervous System Disorder SIDER
Neuropathy Peripheral MetaADEDB
No Therapeutic Response MetaADEDB
Nodule MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Occupational Problem Environmental MetaADEDB
Ocular Discomfort ADReCS
Ocular Hyperaemia ADReCS
Oedema ADReCS
Onychoclasis MetaADEDB
Optic Ischaemic Neuropathy MetaADEDB
Oral Disorder MetaADEDB
Osteopenia MetaADEDB
Pain MetaADEDB
Palpitation MetaADEDB
Pancreatitis MetaADEDB
Periorbital Haematoma MetaADEDB
Photophobia ADReCS
Pollakiuria MetaADEDB
Post Procedural Complication MetaADEDB
Pruritus ADReCS
Punctate Keratitis ADReCS
Radius Fracture MetaADEDB
Rales MetaADEDB
Renal Function Test Abnormal MetaADEDB
Residual Urine MetaADEDB
Retinal Tear MetaADEDB
Scab ADReCS
Scar ADReCS
Scleral Disorder MetaADEDB
Scleritis MetaADEDB
Seborrhoeic Keratosis MetaADEDB
Sensation Of Foreign Body ADReCS
Sensory Loss MetaADEDB
Sinusitis ADReCS
Skin Laceration MetaADEDB
Sleep Walking MetaADEDB
Sleep-Related Eating Disorder MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Sticky Skin ADReCS
Tenosynovitis MetaADEDB
Tongue Disorder MetaADEDB
Trabeculectomy MetaADEDB
Ulcer ADReCS
Ulcerative Keratitis ADReCS
Ulna Fracture MetaADEDB
Unevaluable Event MetaADEDB
Urine Odour Abnormal MetaADEDB
Vascular Injury MetaADEDB
Vascular Rupture MetaADEDB
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Disturbance MetaADEDB
Vitreous Detachment ADReCS
Vomiting ADReCS
Wheeze MetaADEDB
Wound Haemorrhage MetaADEDB

InAADR: Drug-Protein-ADRs database