InAADR

Drug Information

Drug Name: Mercuric Chloride (7487-94-7)
PubChem ID: 24085
SMILES: Cl[Hg]Cl
InchiKey: LWJROJCJINYWOX-UHFFFAOYSA-L
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 271.496
LogP: 1.3765
Ring Count: 0
Hydrogen Bond Acceptor Count: 0
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 0

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Autoimmune Syndrome Myeloperoxidase precursor (P05164) Mercuric chloride (HgCl2) treatment induces an autoimmune syndrome in the Brown Norway (BN) rat when anti-myeloperoxidase (MPO) and anti-glomerular basement (GBM) antibodies are present. [ ADR Type 3 ] Use of methyl prednisolone and antioxidants in mercuric chloride-induced experimental vasculitis
Autoimmune Syndrome And Necrotizing Leucocytoclastic Vasculitis Thiopurine S-methyltransferase (P51580) Mercuric chloride (HgCl2) treatment induces an autoimmune syndrome and necrotizing leucocytoclastic vasculitis in the Brown Norway (BN) rat. [ ADR Type 5 ] Human lymphocyte thiopurine methyltransferase pharmacogenetics: effect of phenotype on 6-mercaptopurine-induced inhibition of mitogen stimulation
Consequences Upon Renal Function And Metabolism Dipeptidylpeptidase IV (P42658) Dipeptidylpeptidase IV activities were markedly decreased (p [ ADR Type 1 ] IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis
Important Consequences Upon Renal Function And Metabolism Aminopeptidase N (P15144) Kidney cortex aminopeptidase N activities were markedly decreased (p [ ADR Type 1 ] IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis
Important Consequences Upon Renal Function And Metabolism Angiotensinase A (P42785) Angiotensinase A activities were markedly decreased (p [ ADR Type 1 ] IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis
Leucocytoclastic Vasculitis Myeloperoxidase precursor (P05164) Mercuric chloride (HgCl2) treatment induces an necrotizing leucocytoclastic vasculitis in the Brown Norway (BN) rat when anti-myeloperoxidase (MPO) and anti-glomerular basement (GBM) antibodies are present. [ ADR Type 3 ] Use of methyl prednisolone and antioxidants in mercuric chloride-induced experimental vasculitis

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

InAADR: Drug-Protein-ADRs database