InAADR

Drug Information

Drug Name: Alprostadil (745-65-3)
PubChem ID: 5280723
SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O
InchiKey: GMVPRGQOIOIIMI-DWKJAMRDSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 354.487
LogP: 3.4751
Ring Count: 0
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 94.83

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abnormal Ejaculation SIDER
Abscess MetaADEDB
Accidental Injury ADReCS
Accidental Needle Stick MetaADEDB
Acidosis MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Anaemia ADReCS
Anal Cancer MetaADEDB
Aneurysm MetaADEDB
Angiopathy ADReCS
Anorectal Disorder MetaADEDB
Anoxia MetaADEDB
Anuria ADReCS
Aortic Valve Disease MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Application Site Erythema MetaADEDB
Application Site Pain MetaADEDB
Arm Amputation MetaADEDB
Arrhythmias Cardiac MetaADEDB
Arterial Occlusive Diseases MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Obliterans MetaADEDB
Arteriospasm Coronary MetaADEDB
Arteriovenous Malformation MetaADEDB
Asthenia ADReCS
Atherosclerosis Obliterans MetaADEDB
Atrioventricular Block ADReCS
Atrioventricular Block Second Degree ADReCS
Back Pain ADReCS
Balanitis ADReCS
Barrett Oesophagus MetaADEDB
Bartter Syndrome MetaADEDB
Base Excess MetaADEDB
Base Excess Negative MetaADEDB
Birth Trauma MetaADEDB
Bladder Cancer MetaADEDB
Bladder Inflammation MetaADEDB
Block Heart MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Blister MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Ph Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Decreased ADReCS
Body Temperature Increased ADReCS
Bradycardia ADReCS
Bradypnoea ADReCS
Brain Cancer Metastatic MetaADEDB
Brain Herniation MetaADEDB
Burning Feeling Vagina SIDER
Bursitis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cancer Pain MetaADEDB
Carbon Dioxide Increased ADReCS
Carcinoma Of Prostate MetaADEDB
Cardiac Arrest ADReCS
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiac Index Decreased MetaADEDB
Cardiovascular Disorder MetaADEDB
Carotid Artery Thrombosis MetaADEDB
Catalepsy MetaADEDB
Cauda Equina Syndrome MetaADEDB
Cerebral Haemorrhage ADReCS
Cerebral Hemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cervical Vertebral Fracture MetaADEDB
Chill MetaADEDB
Cholestasis MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Colonic Polyp MetaADEDB
Condition Aggravated MetaADEDB
Congenital Infection MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Pulmonary Valve Atresia MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Convulsion ADReCS
Coronary Artery Restenosis MetaADEDB
Coronary Stenosis MetaADEDB
Cough ADReCS
Cramp Muscle MetaADEDB
Cramps Of Lower Extremities MetaADEDB
Cystitis Viral MetaADEDB
Deafness Neurosensory MetaADEDB
Decreased Libido MetaADEDB
Deep Vein Thromboses MetaADEDB
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Device Breakage MetaADEDB
Device Failure MetaADEDB
Device Malfunction MetaADEDB
Dialysis MetaADEDB
Diarrhoea ADReCS
Dilatation Ventricular MetaADEDB
Discomfort ADReCS
Disease Complication MetaADEDB
Disseminated Intravascular Coagulation ADReCS
Dizziness ADReCS
Drug Administration Error MetaADEDB
Drug Effect Decreased MetaADEDB
Drug Ineffective MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Duodenal Ulcer MetaADEDB
Dysarthria MetaADEDB
Dyskinesia Drug-Induced MetaADEDB
Dyspareunia MetaADEDB
Dyspnea MetaADEDB
Dysuria ADReCS
Ecchymosis ADReCS
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Edema MetaADEDB
Ejaculation Disorder ADReCS
Ejection Fraction Decreased MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Embolism Venous MetaADEDB
Endotoxic Shock MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Percentage Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Erectile Dysfunction MetaADEDB
Erection Increased MetaADEDB
Erythema ADReCS
Erythema Multiforme MetaADEDB
Exanthema MetaADEDB
Expired Drug Administered MetaADEDB
Extrasystoles ADReCS
Extrasystoles Ventricular MetaADEDB
Fatty Liver MetaADEDB
Feeling Abnormal ADReCS
Feeling Jittery ADReCS
Feeling Strange SIDER
Fetal Death MetaADEDB
Fever MetaADEDB
Fibrosis ADReCS
Flu Symptoms MetaADEDB
Flushing ADReCS
Foreign Body Trauma MetaADEDB
Fungal Infection ADReCS
Gallbladder Operation MetaADEDB
Gastrointestinal Diseases MetaADEDB
Genital Burning Sensation MetaADEDB
Genital Disorder Male MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Glomerulonephritis MetaADEDB
Graft Dysfunction MetaADEDB
Haematoma ADReCS
Haematotoxicity MetaADEDB
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemoglobin ADReCS
Haemolytic Anaemia MetaADEDB
Haemorrhage ADReCS
Haemorrhage Urinary Tract ADReCS
Haemorrhagic Diathesis MetaADEDB
Headache ADReCS
Heart Arrest MetaADEDB
Heart Attack MetaADEDB
Heart Defects Congenital MetaADEDB
Heart Failure MetaADEDB
Heart Rate Increased ADReCS
Heart-Lung Transplant Rejection MetaADEDB
Hematoma MetaADEDB
Hepatectomy MetaADEDB
Hepatic Artery Stenosis MetaADEDB
Hernia Repair MetaADEDB
Herpes Zoster MetaADEDB
Hiccough MetaADEDB
Hyperaemia ADReCS
Hyperalgesia MetaADEDB
Hyperamylasaemia MetaADEDB
Hyperbilirubinaemia ADReCS
Hypercapnia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hyperostosis Cortical Congenital MetaADEDB
Hypertension ADReCS
Hypertension Pulmonary MetaADEDB
Hypertrichosis MetaADEDB
Hypertrophy ADReCS
Hypoaesthesia ADReCS
Hypoglycaemia ADReCS
Hypokalaemia ADReCS
Hypotension ADReCS
Hypothermia ADReCS
Idiopathic Thrombocytopenic Purpura MetaADEDB
Impotence Vasculogenic MetaADEDB
Incisional Hernia MetaADEDB
Incorrect Dose Administered MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infantile Apnoeic Attack MetaADEDB
Infection ADReCS
Inflammation ADReCS
Influenza ADReCS
Infusion Related Reaction MetaADEDB
Infusion Site Extravasation MetaADEDB
Injection Site Bruising SIDER
Injection Site Discomfort MetaADEDB
Injection Site Haematoma ADReCS
Injection Site Haemorrhage ADReCS
Injection Site Inflammation ADReCS
Injection Site Irritation MetaADEDB
Intentional Drug Misuse MetaADEDB
Intestinal Haemorrhage MetaADEDB
Irritability ADReCS
Irritation Skin MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Ischemia MetaADEDB
Ischemic Attack Transient MetaADEDB
Joint Hyperextension ADReCS
Kidney Transplant MetaADEDB
Leg Amputation MetaADEDB
Leg Cramps ADReCS
Leg Pain ADReCS
Lethargy ADReCS
Liver Diseases MetaADEDB
Loss Of Consciousness ADReCS
Low Cardiac Output Syndrome MetaADEDB
Lung Adenocarcinoma MetaADEDB
Lung Cancer Metastatic MetaADEDB
Lung Edema MetaADEDB
Lymphatic Diseases MetaADEDB
Lymphatic Duct Rupture MetaADEDB
Lymphoma MetaADEDB
Lymphoplasmacytoid Lymphoma/Immunocytoma MetaADEDB
Markedly Reduced Dietary Intake MetaADEDB
Medical Device Complication MetaADEDB
Metrorrhagia ADReCS
Micturition Urgency ADReCS
Motor Retardation MetaADEDB
Mucocutaneous Lymph Node Syndrome MetaADEDB
Mucosal Membrane Hyperplasia MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Musculoskeletal Stiffness ADReCS
Mydriasis ADReCS
Myocardial Infarction MetaADEDB
Myocardial Ischemia MetaADEDB
Myoglobin Blood Increased MetaADEDB
Nasal Congestion ADReCS
Nausea ADReCS
Necrosis MetaADEDB
Neonatal Cardiac Failure MetaADEDB
Neonatal Hyponatraemia MetaADEDB
Neonatal Tachypnoea MetaADEDB
Neoplasm ADReCS
Neoplasm Recurrence MetaADEDB
Neoplasm Skin ADReCS
Nephroangiosclerosis MetaADEDB
Nervousness ADReCS
Neuroblastoma Recurrent MetaADEDB
Neurogenic Bladder MetaADEDB
Neutropenic Infection MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Numbness MetaADEDB
Oedema ADReCS
Oliguria MetaADEDB
Open Wound MetaADEDB
Oral Intake Reduced MetaADEDB
Oropharyngeal Pain MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pain Localised SIDER
Painful Erection ADReCS
Pancreas Lipomatosis MetaADEDB
Pancreatic Enzymes Increased MetaADEDB
Paraesthesia Of Genital Male MetaADEDB
Patent Ductus Arteriosis MetaADEDB
Pelvic Pain ADReCS
Penile Abscess MetaADEDB
Penile Induration MetaADEDB
Penile Infection MetaADEDB
Penile Oedema SIDER
Penile Operation MetaADEDB
Penile Pain ADReCS
Penile Swelling MetaADEDB
Penis Deviation MetaADEDB
Penis Disorder ADReCS
Perineal Pain ADReCS
Periostitis Hypertrophic MetaADEDB
Peripheral Arterial Disease MetaADEDB
Peripheral Arterial Occlusive Disease MetaADEDB
Peripheral Vascular Disorder ADReCS
Peritonitis ADReCS
Peyronie Disease SIDER
Pharmaceutical Product Complaint MetaADEDB
Phimosis ADReCS
Phlebitis MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Po2 Decreased MetaADEDB
Pollakiuria ADReCS
Polyarteritis Nodosa MetaADEDB
Poor Quality Drug Administered MetaADEDB
Portal Vein Thrombosis MetaADEDB
Post Herpetic Neuralgia MetaADEDB
Post Procedural Complication MetaADEDB
Postoperative Complications MetaADEDB
Priapism ADReCS
Product Quality Issue MetaADEDB
Prostatic Disorder ADReCS
Prostatic Operation MetaADEDB
Prostatitis ADReCS
Prostatomegaly MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Pulmonary Arrest MetaADEDB
Pulmonary Artery Atresia MetaADEDB
Pulmonary Atresia MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Embolism MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Infarction MetaADEDB
Purulence MetaADEDB
Pyelonephritis Acute MetaADEDB
Pyrexia ADReCS
Radical Prostatectomy MetaADEDB
Rash ADReCS
Rash Generalised MetaADEDB
Raynaud Disease MetaADEDB
Regurgitation ADReCS
Renal Cyst MetaADEDB
Respiratory Depression ADReCS
Respiratory Distress ADReCS
Respiratory Distress Syndrome Adult MetaADEDB
Respiratory Rate Decreased ADReCS
Respiratory Rate Increased MetaADEDB
Respiratory Tract Infection ADReCS
Retrograde Amnesia MetaADEDB
Rhinitis ADReCS
Rhonchi MetaADEDB
Scleroderma Systemic MetaADEDB
Scrotal Disorder ADReCS
Scrotal Oedema ADReCS
Seizures MetaADEDB
Sensory Loss ADReCS
Sepsis ADReCS
Serum Creatinine Increased MetaADEDB
Shock ADReCS
Sinusitis ADReCS
Skin Discolouration MetaADEDB
Skin Diseases Vascular MetaADEDB
Skin Ulcer MetaADEDB
Sputum Culture Positive MetaADEDB
Stiffness SIDER
Streptococcal Bacteraemia MetaADEDB
Stroke MetaADEDB
Supraventricular Extrasystoles ADReCS
Supraventricular Tachycardia ADReCS
Sweating Increased MetaADEDB
Swelling ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tachypnoea ADReCS
Tension ADReCS
Testes Pain MetaADEDB
Testicular Disorder ADReCS
Testicular Pain ADReCS
Tetralogy Of Fallot MetaADEDB
Therapy Non-Responder MetaADEDB
Thromboangiitis Obliterans MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis MetaADEDB
Thrombotic Microangiopathy MetaADEDB
Tight Foreskin SIDER
Treatment Failure MetaADEDB
Troponin I Increased MetaADEDB
Unresponsive To Verbal Stimuli MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upper Respiratory Tract Inflammation MetaADEDB
Urethral Burning On Micturition ADReCS
Urethral Disorder ADReCS
Urethral Haemorrhage ADReCS
Urethral Pain ADReCS
Urinary Tract Disorder MetaADEDB
Urination Impaired ADReCS
Urine Osmolarity Increased MetaADEDB
Vascular Calcification MetaADEDB
Vascular Graft MetaADEDB
Vascular Injury MetaADEDB
Vascular Operation MetaADEDB
Vasodilation MetaADEDB
Vasodilation Procedure ADReCS
Vein Disorder MetaADEDB
Vena Cava Filter Insertion MetaADEDB
Ventricular Fibrillation ADReCS
Vessel Puncture Site Haematoma MetaADEDB
Vomiting MetaADEDB
Vulvovaginal Burning Sensation ADReCS
Weakness MetaADEDB
Weight Decrease Neonatal MetaADEDB
Wheelchair User MetaADEDB
Wheezing ADReCS
Wound Haemorrhage MetaADEDB
Wrist Fracture MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB
Yeast Infection SIDER

InAADR: Drug-Protein-ADRs database