InAADR

Drug Information

Drug Name: imipenem (74431-23-5)
PubChem ID: 5282372
SMILES: C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O
InchiKey: GSOSVVULSKVSLQ-JJVRHELESA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 317.367
LogP: -1.2104
Ring Count: 0
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 147.72

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Tenderness MetaADEDB
Abscess Bacterial MetaADEDB
Acidosis MetaADEDB
Acquired Methaemoglobinaemia MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myeloblastic Leukemia MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adrenal Cortex Necrosis MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Allergies MetaADEDB
Anaemia MetaADEDB
Anaemia Of Chronic Disease MetaADEDB
Anorexia MetaADEDB
Anuria MetaADEDB
Aortic Aneurysm MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriospasm Coronary MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asystole MetaADEDB
Ataxia MetaADEDB
Automatism MetaADEDB
Axillary Vein Thrombosis MetaADEDB
Azotaemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bicytopenia MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Inflammation MetaADEDB
Blood Bicarbonate Decreased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Urea Increased MetaADEDB
Blood Urine Present MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Disorder MetaADEDB
Bone Marrow Failure MetaADEDB
Brain Diseases MetaADEDB
Brain Herniation MetaADEDB
Brain Oedema MetaADEDB
Bronchoalveolar Lavage MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Caecitis MetaADEDB
Caesarean Section MetaADEDB
Candida Infection MetaADEDB
Capillary Leak Syndrome MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cardiovascular Disorder MetaADEDB
Catheter Related Infection MetaADEDB
Cell Death MetaADEDB
Central Venous Pressure Decreased MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Cholecystitis Acute MetaADEDB
Chronic Kidney Disease MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Cmv Infection MetaADEDB
Colitis Ischaemic MetaADEDB
Colitis Pseudomembranous MetaADEDB
Condition Aggravated MetaADEDB
Crossmatch Incompatible MetaADEDB
Cyanosis MetaADEDB
Death MetaADEDB
Deep Vein Thromboses MetaADEDB
Dermatitis Bullous MetaADEDB
Diabetes MetaADEDB
Dialysis MetaADEDB
Diarrhea MetaADEDB
Dislocation MetaADEDB
Disorder Lung MetaADEDB
Disseminated Tuberculosis MetaADEDB
Drug Eruptions MetaADEDB
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Electromechanical Dissociation MetaADEDB
Embolism Pulmonary MetaADEDB
Emphysema MetaADEDB
Encephalitis MetaADEDB
Encephalopathy MetaADEDB
Endocarditis MetaADEDB
Enteritis Infectious MetaADEDB
Enterobacteriaceae Infections MetaADEDB
Enterococcal Bacteraemia MetaADEDB
Enterococcal Infection MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epiglottitis MetaADEDB
Eruption MetaADEDB
Erythema MetaADEDB
Erythema Multiforme MetaADEDB
Escherichia Bacteraemia MetaADEDB
Escherichia Sepsis MetaADEDB
Esophageal Cancer MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Febrile Neutropenia MetaADEDB
Fungaemia MetaADEDB
Fungal Peritonitis MetaADEDB
Fungus Culture Positive MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Mucosal Lesion MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Oedema MetaADEDB
General Physical Health Deterioration MetaADEDB
Genital Haemorrhage MetaADEDB
Gestational Diabetes MetaADEDB
Glucose Urine MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Trauma MetaADEDB
Hepatitis MetaADEDB
Hepatitis Fulminant MetaADEDB
Hepatotoxicity MetaADEDB
Herpes Simplex Hepatitis MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypokalaemia MetaADEDB
Hypovolaemia MetaADEDB
Hypovolaemic Shock MetaADEDB
Hypoxia MetaADEDB
Hypoxic Encephalopathy MetaADEDB
Ild MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Intra-abdominal haematoma MetaADEDB
Ischaemic Hepatitis MetaADEDB
Jaw Fracture MetaADEDB
Kidney Diseases MetaADEDB
Kidney Failure MetaADEDB
Kidney Tubular Necrosis Acute MetaADEDB
Laryngotracheitis MetaADEDB
Leucopenia MetaADEDB
Leukoencephalomyelitis MetaADEDB
Lung Edema MetaADEDB
Lung Infection MetaADEDB
Lyell MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphocytes Decreased MetaADEDB
Malabsorption MetaADEDB
Mastitis Bacterial MetaADEDB
Meningitis Bacterial MetaADEDB
Mouth Bleeding MetaADEDB
Multi-Organ Failure MetaADEDB
Mycobacterium Abscessus Infection MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myoclonus MetaADEDB
Neumonia MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Oesophageal Varices Haemorrhage MetaADEDB
Oliguria MetaADEDB
Oral Herpes MetaADEDB
Oral Intake Reduced MetaADEDB
Oral Mucosa Erosion MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pancreatic Insufficiency MetaADEDB
Pancreatic Necrosis MetaADEDB
Parotitis MetaADEDB
Pathogen Resistance MetaADEDB
Pericardial Drainage MetaADEDB
Pericardial Effusion MetaADEDB
Peritoneal Adhesions MetaADEDB
Petechia MetaADEDB
Platelet Count MetaADEDB
Pneumococcal Infections MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Pneumonia Streptococcal MetaADEDB
Preventive Surgery MetaADEDB
Prostatitis MetaADEDB
Prothrombin Time MetaADEDB
Pseudomonas Infection MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Artery Thrombosis MetaADEDB
Refusal Of Treatment By Relative MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Reticulocyte Count Decreased MetaADEDB
Scrotal Abscess MetaADEDB
Seizures MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Serratia Infection MetaADEDB
Serum Sickness MetaADEDB
Skin Desquamation MetaADEDB
Skin Dystrophy MetaADEDB
Skin Erosion MetaADEDB
Skin Necrosis MetaADEDB
Skin Ulcer Haemorrhage MetaADEDB
Soliloquy MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Infection MetaADEDB
Status Epilepticus MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subclavian Vein Thrombosis MetaADEDB
T-Cell Lymphoma MetaADEDB
Testicular Mass MetaADEDB
Therapy Non-Responder MetaADEDB
Thoracic Cavity Drainage MetaADEDB
Toxic Skin Eruption MetaADEDB
Tremor MetaADEDB
Tubulointerstitial Nephritis MetaADEDB
Type Iv Hypersensitivity Reaction MetaADEDB
Ulcer Haemorrhage MetaADEDB
Urobilin Urine Present MetaADEDB
Urticaria MetaADEDB
Uterine Contractions Abnormal MetaADEDB
Venoocclusive Disease MetaADEDB
Vomiting MetaADEDB
Wound Infection MetaADEDB

InAADR: Drug-Protein-ADRs database