InAADR

Drug Information

Drug Name: Methylnaltrexone (73232-52-7)
PubChem ID: 5361918
SMILES: C[N+]1(CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O)CC6CC6
InchiKey: JVLBPIPGETUEET-GAAHOAFPSA-O
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 356.442
LogP: 1.67
Ring Count: 1
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 66.76

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Tenderness ADReCS
Abnormal Bowel Sounds SIDER
Abscess ADReCS
Abscess Neck ADReCS
Acquired Immunodeficiency Syndrome ADReCS
Acute Coronary Syndrome ADReCS
Agitation ADReCS
Albumin Low SIDER
Altered State Of Consciousness ADReCS
Anaemia ADReCS
Anal Haemorrhage SIDER
Aneurysm ADReCS
Aneurysm Ruptured ADReCS
Angiopathy ADReCS
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphasia ADReCS
Aphthous Stomatitis ADReCS
Apnoea ADReCS
Arrhythmia ADReCS
Arthralgia ADReCS
Ascites ADReCS
Aspiration ADReCS
Asthenia ADReCS
Back Pain ADReCS
Bacteraemia ADReCS
Balance Disorder ADReCS
Bedridden ADReCS
Bladder Pain ADReCS
Bladder Spasm ADReCS
Bleeding Time Prolonged ADReCS
Blood Albumin Decreased ADReCS
Blood Creatinine Increased ADReCS
Blood Potassium Decreased ADReCS
Blood Pressure Increased ADReCS
Body Temperature Increased ADReCS
Borborygmi SIDER
Bradycardia ADReCS
Breast Cancer ADReCS
Breast Disorder SIDER
Breath Sounds Abnormal SIDER
Bronchitis ADReCS
Bunion ADReCS
Ca++ Increased SIDER
Calcium Low SIDER
Cancer Pain ADReCS
Candidiasis ADReCS
Cardiac Arrest ADReCS
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Murmur ADReCS
Cardiovascular Disorder ADReCS
Cellulitis ADReCS
Cerebrovascular Accident ADReCS
Cerumen Impaction ADReCS
Chest Pain ADReCS
Chills ADReCS
Chronic Obstructive Pulmonary Disease ADReCS
Clostridial Infection ADReCS
Cold Sweat ADReCS
Colonic Pseudo-Obstruction ADReCS
Coma ADReCS
Confusional State ADReCS
Connective Tissue Disorder SIDER
Convulsion ADReCS
Coordination Abnormal ADReCS
Copd Exacerbation SIDER
Cough ADReCS
Creatinine Increased SIDER
Cyanosis ADReCS
Cyst ADReCS
Death ADReCS
Decubitus Ulcer ADReCS
Dehydration ADReCS
Delirium ADReCS
Delusion ADReCS
Dementia ADReCS
Dementia Alzheimer Type ADReCS
Depressed Level Of Consciousness ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Disease Progression ADReCS
Disorientation ADReCS
Disseminated Intravascular Coagulation ADReCS
Dizziness ADReCS
Drooling ADReCS
Drug Withdrawal Syndrome ADReCS
Dry Mouth ADReCS
Dysarthria ADReCS
Dysphagia ADReCS
Dyspnoea ADReCS
Ecchymosis ADReCS
Effusion ADReCS
Embolism ADReCS
Emphysema ADReCS
Epistaxis ADReCS
Erythema ADReCS
Eye Disorder SIDER
Failure To Thrive ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Cold ADReCS
Feeling Cool SIDER
Fibrosis ADReCS
Fistula ADReCS
Flatulence ADReCS
Fluid Retention ADReCS
Flushing ADReCS
Furuncle ADReCS
Gallop Rhythm SIDER
Gallop Rhythm Present ADReCS
Gastric Disorder ADReCS
Gastric Ulcer ADReCS
Gastric Ulcer Haemorrhage ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Gastrointestinal Perforation ADReCS
Gastrointestinal Sounds Abnormal ADReCS
Gastrooesophageal Reflux Disease ADReCS
Generalised Oedema ADReCS
Haematoma ADReCS
Haematuria ADReCS
Haemoglobin ADReCS
Haemoglobin Decreased ADReCS
Haemorrhage ADReCS
Haemorrhoids ADReCS
Hallucination ADReCS
Headache ADReCS
Heart Rate Irregular ADReCS
Heart Sounds Abnormal ADReCS
Hot Flush ADReCS
Hypercalcaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperkalaemia ADReCS
Hypoaesthesia ADReCS
Hypocalcaemia ADReCS
Hypoglycaemia ADReCS
Hypoglycaemic Seizure SIDER
Hypokalaemia ADReCS
Hyponatraemia ADReCS
Hypotension ADReCS
Hypoventilation ADReCS
Hypoxia ADReCS
Ileus ADReCS
Infarction ADReCS
Infection ADReCS
Infestation SIDER
Infestation Nos SIDER
Inflammation ADReCS
Infusion Related Reaction ADReCS
Injection Site Erythema PROTECT
Injection Site Oedema PROTECT
Injection Site Pain ADReCS
Injection Site Reaction PROTECT
Insomnia ADReCS
Intractable Pain SIDER
Ischaemia ADReCS
Kyphosis ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Lethargy ADReCS
Lung Disorder ADReCS
Lung Infiltration ADReCS
Lymphadenopathy ADReCS
Malaise ADReCS
Mediastinal Disorder SIDER
Menopausal Symptoms ADReCS
Mental Disorder SIDER
Monocyte Count Increased ADReCS
Mucosal Inflammation ADReCS
Muscle Spasms ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Myoclonus ADReCS
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Pain ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Neoplasm Progression SIDER
Nervous System Disorder SIDER
Nervousness ADReCS
Neutropenia ADReCS
Night Sweats ADReCS
Obstruction ADReCS
Oedema ADReCS
Oedema Genital ADReCS
Oedema Peripheral ADReCS
Oesophageal Obstruction ADReCS
Onychomadesis ADReCS
Oral Candidiasis ADReCS
Organ Failure ADReCS
Oropharyngeal Pain ADReCS
Orthostatic Hypotension ADReCS
Osteoarthritis ADReCS
Osteomyelitis ADReCS
Pain ADReCS
Pain Aggravated ADReCS
Pain Worsened SIDER
Pancreatitis ADReCS
Paraparesis ADReCS
Partial Seizures ADReCS
Pathological Fracture ADReCS
Peptic Ulcer ADReCS
Pharyngolaryngeal Pain SIDER
Physical Abuse ADReCS
Piloerection ADReCS
Platelet Count Decreased ADReCS
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Pneumonia Aspiration ADReCS
Polyp ADReCS
Potassium Low SIDER
Proctalgia SIDER
Productive Cough ADReCS
Protein Total Decreased ADReCS
Pruritus ADReCS
Pseudomonal Sepsis ADReCS
Psoriasis ADReCS
Pulmonary Congestion ADReCS
Pulmonary Embolism ADReCS
Pulmonary Fibrosis ADReCS
Pulmonary Oedema ADReCS
Rales ADReCS
Rectal Haemorrhage ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment ADReCS
Respiratory Arrest ADReCS
Respiratory Distress ADReCS
Respiratory Failure ADReCS
Respiratory Rate Decreased ADReCS
Respiratory Sounds Decreased SIDER
Respiratory Tract Congestion ADReCS
Respiratory Tract Infection ADReCS
Retching ADReCS
Rhinorrhoea ADReCS
Rhonchi ADReCS
Salivary Hypersecretion ADReCS
Sedation ADReCS
Seizures SIDER
Sensation Of Heaviness ADReCS
Sepsis ADReCS
Septic Shock ADReCS
Shock ADReCS
Shoulder Pain ADReCS
Simple Partial Seizures ADReCS
Skin Infection ADReCS
Skin Turgor Decreased ADReCS
Skin Ulcer ADReCS
Somnolence ADReCS
Speech Disorder ADReCS
Stomatitis ADReCS
Suicidal Ideation ADReCS
Sweating SIDER
Tachycardia ADReCS
Tenderness ADReCS
Tension ADReCS
Tinnitus ADReCS
Tongue Coated ADReCS
Tooth Impacted ADReCS
Tremor ADReCS
Ulcer ADReCS
Ulcer Haemorrhage ADReCS
Upset Stomach SIDER
Urethral Disorder SIDER
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Verbal Abuse ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weight Increased ADReCS
Wheezing ADReCS
Withdrawal Syndrome ADReCS
Wound Dehiscence ADReCS
Yawning ADReCS
Yellow Skin ADReCS

InAADR: Drug-Protein-ADRs database