InAADR

Drug Information

Drug Name: Dantrolene (7261-97-4)
PubChem ID: 6914273
SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]
InchiKey: OZOMQRBLCMDCEG-VIZOYTHASA-N
Therapeutic Category: Central Nervous System Agents, Muscle Relaxants, Neuromuscular Agents, Peripheral Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 314.257
LogP: 1.7405
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 118.05

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Cramp SIDER
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abnormal Ecg MetaADEDB
Abscess Bacterial MetaADEDB
Abulia MetaADEDB
Acidosis MetaADEDB
Acne ADReCS
Acute Hepatic Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adh Inappropriate MetaADEDB
Adhesion MetaADEDB
Adynamic Ileus MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergic Alveolitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Aminoaciduria MetaADEDB
Anaemia ADReCS
Anal Fissure MetaADEDB
Anaphylactic Reaction ADReCS
Anaphylactic Shock ADReCS
Anemia Aplastic MetaADEDB
Aneurysm MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anisocytosis MetaADEDB
Anorexia ADReCS
Antithrombin Iii Decreased MetaADEDB
Apathy MetaADEDB
Aplastic Anaemia ADReCS
Areflexia MetaADEDB
Arrhythmia MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia ADReCS
Asthenia ADReCS
Atelectasis MetaADEDB
Atrioventricular Block MetaADEDB
Automatism MetaADEDB
Autonomic Instability MetaADEDB
Back Pain ADReCS
Band Neutrophil Percentage Increased MetaADEDB
Bence Jones Protein Urine MetaADEDB
Benign Neoplasm Of Thyroid Gland MetaADEDB
Black Stools MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Retention MetaADEDB
Bleeding Vaginal MetaADEDB
Blood Acid Phosphatase Increased MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Increased MetaADEDB
Blood Creatine Phosphokinase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Erythropoietin Increased MetaADEDB
Blood Immunoglobulin A Decreased MetaADEDB
Blood Insulin MetaADEDB
Blood Insulin Increased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Parathyroid Hormone Increased MetaADEDB
Blood Pressure Fluctuation ADReCS
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Failure MetaADEDB
Brain Death MetaADEDB
C-Reactive Protein Increased MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoma Transitional Cell MetaADEDB
Cardiac Failure ADReCS
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level MetaADEDB
Cardiomyopathies MetaADEDB
Carotid Artery Aneurysm MetaADEDB
Cartilage Development Disorder MetaADEDB
Catatonia MetaADEDB
Catheter Related Infection MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Palsy MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chills ADReCS
Choking Sensation ADReCS
Cholangiolitis MetaADEDB
Cholestasis MetaADEDB
Chronic Lymphocytic Leukaemia ADReCS
Coagulopathy SIDER
Colitis Ischaemic MetaADEDB
Coma MetaADEDB
Compression Fracture MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Eye Naevus MetaADEDB
Consciousness Fluctuating MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Cramp Muscle SIDER
Crystal Urine ADReCS
Crystalluria ADReCS
Csf Neutrophil Count Increased MetaADEDB
Cyanosis MetaADEDB
Cyanosis Central MetaADEDB
Cytolytic Hepatitis MetaADEDB
Death ADReCS
Decreased Appetite ADReCS
Deglutition Disorder MetaADEDB
Delusion MetaADEDB
Dementia With Lewy Bodies MetaADEDB
Dental Operation MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Depression ADReCS
Depression Suicidal MetaADEDB
Depressive Symptom MetaADEDB
Dermatitis ADReCS
Dermatitis Acneiform ADReCS
Device Related Infection MetaADEDB
Diabetic Gangrene MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disease Recurrence MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drooling ADReCS
Drowsiness SIDER
Drug Interaction Potentiation MetaADEDB
Drug Toxicity MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Duodenitis MetaADEDB
Dysgeusia ADReCS
Dysphagia ADReCS
Easy Bruisability MetaADEDB
Eating Disorder Symptom MetaADEDB
Eczema ADReCS
Effusion ADReCS
Electrocardiogram Pr Prolongation MetaADEDB
Embolism Pulmonary MetaADEDB
End-Tidal Co2 Increased MetaADEDB
Endometrial Cancer MetaADEDB
Enema Administration MetaADEDB
Enlarged Liver MetaADEDB
Enzyme Inhibition MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilia ADReCS
Epilepsy MetaADEDB
Erectile Dysfunction ADReCS
Eruption SIDER
Erythema ADReCS
Erythema Multiforme MetaADEDB
Escherichia Infection MetaADEDB
Excess Potassium MetaADEDB
Excessive Salivation MetaADEDB
Extravasation ADReCS
Fanconi Syndrome MetaADEDB
Fasciculation MetaADEDB
Fatigue ADReCS
Feeling Abnormal ADReCS
Femoral Neck Fracture MetaADEDB
Fever MetaADEDB
Fever Chills SIDER
Fib MetaADEDB
Flatulence MetaADEDB
Furuncle MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Irritation SIDER
Gastric Ulcer Haemorrhage MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Motility Disorder MetaADEDB
Gastrointestinal Pain ADReCS
Gaucher Disease MetaADEDB
Gingival Hypertrophy MetaADEDB
Gingivectomy MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Haematochezia MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemorrhage ADReCS
Hair Growth Abnormal ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Hearing Loss Bilateral MetaADEDB
Hearing Loss Sensorineural MetaADEDB
Hearing Loss Sudden MetaADEDB
Heart Arrest MetaADEDB
Heart Failure MetaADEDB
Heart Rate Increased MetaADEDB
Heat Stroke MetaADEDB
Hematuria MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal MetaADEDB
Hepatitis ADReCS
Hepatitis A MetaADEDB
Hepatitis B MetaADEDB
Hepatitis Chronic MetaADEDB
Hepatitis Fulminant MetaADEDB
Human Herpesvirus 6 Infection MetaADEDB
Hydrothorax MetaADEDB
Hyperhidrosis ADReCS
Hyperkalemia MetaADEDB
Hypersensitivity ADReCS
Hypertonia MetaADEDB
Hypertonic Bladder MetaADEDB
Hypertrophic Cardiomyopathy MetaADEDB
Hypogammaglobulinaemia MetaADEDB
Hypoxic Encephalopathy MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Ill-Defined Disorder ADReCS
Immunoglobulins Decreased MetaADEDB
Impaired Healing MetaADEDB
Incontinence ADReCS
Infection MetaADEDB
Infection Urinary Tract MetaADEDB
Inflammatory Bowel Disease MetaADEDB
Infusion Related Reaction MetaADEDB
Injection Site Infection MetaADEDB
Injection Site Reaction ADReCS
Injection Site Ulcer MetaADEDB
Injury Asphyxiation MetaADEDB
Insomnia ADReCS
International Normalised Ratio Fluctuation MetaADEDB
Intestinal Obstruction ADReCS
Intracranial Aneurysm MetaADEDB
Jaundice MetaADEDB
Judgement Impaired MetaADEDB
Kidney Failure MetaADEDB
Labile Blood Pressure MetaADEDB
Laboratory Test Interference MetaADEDB
Lacrimation SIDER
Lacrimation Increased ADReCS
Leukemia Lymphocytic Chronic B-Cell MetaADEDB
Leukopenia ADReCS
Light Chain Disease MetaADEDB
Lightheadedness SIDER
Lymphocytic Lymphoma ADReCS
Lymphoma ADReCS
Macrocytosis MetaADEDB
Malabsorption MetaADEDB
Malaise ADReCS
Malignant Hyperthermia MetaADEDB
Malignant Syndrome Nos SIDER
Micturition Disorder ADReCS
Miyoshi Myopathy MetaADEDB
Mucosal Inflammation MetaADEDB
Multi-Organ Disorder MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Sclerosis MetaADEDB
Multiple Sclerosis Relapse MetaADEDB
Muscle Hypertonia MetaADEDB
Muscle Injury MetaADEDB
Muscle Necrosis MetaADEDB
Muscle Rigidity MetaADEDB
Muscle Spasms ADReCS
Muscle Tightness MetaADEDB
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness MetaADEDB
Mutism MetaADEDB
Myalgia ADReCS
Myelodysplasia MetaADEDB
Myoclonus MetaADEDB
Nausea ADReCS
Necrosis ADReCS
Nephrolithiasis MetaADEDB
Nephrotic Syndrome MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuroleptic Malignant Syndrome ADReCS
Nocturia ADReCS
Nuclear Magnetic Resonance Imaging Brain Abnormal MetaADEDB
Nystagmus MetaADEDB
Obstruction ADReCS
Oedema ADReCS
Oliguria MetaADEDB
Optic Nerve Disorder MetaADEDB
Oral Discomfort MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Pancreatic Duct Dilatation MetaADEDB
Paraplegia MetaADEDB
Pericarditis ADReCS
Persecutory Delusion MetaADEDB
Phlebitis ADReCS
Physical Disability MetaADEDB
Platelet Count MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pleural Fibrosis MetaADEDB
Pleurisy MetaADEDB
Pneumonia MetaADEDB
Poikilocytosis MetaADEDB
Pollakiuria ADReCS
Post Procedural Complication MetaADEDB
Protein Total Decreased MetaADEDB
Pruritus ADReCS
Psychiatric Decompensation MetaADEDB
Psychomotor Skills Impaired MetaADEDB
Pulmonary Edema MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Oedema ADReCS
Pyelonephritis Acute MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Reflux Esophagitis MetaADEDB
Renal Failure ADReCS
Renal Tubular Disorder MetaADEDB
Respiratory Depression ADReCS
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Retroperitoneal Haematoma MetaADEDB
Rhabdomyolysis MetaADEDB
Right Ventricular Dysfunction MetaADEDB
Risus Sardonicus MetaADEDB
Seizures SIDER
Sensation Of Heaviness MetaADEDB
Sensory Loss MetaADEDB
Social Avoidant Behaviour ADReCS
Somnolence ADReCS
Spasm MetaADEDB
Speech Disorder ADReCS
Speech Impairment Nos SIDER
Spinal Deformity MetaADEDB
Sputum Abnormal MetaADEDB
Sputum Culture Positive MetaADEDB
Staphylococcal Infection MetaADEDB
Staphylococcal Skin Infection MetaADEDB
Status Epilepticus MetaADEDB
Stomach Ulcer MetaADEDB
Subcutaneous Abscess MetaADEDB
Suffocation Feeling ADReCS
Sweating SIDER
Swelling ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Therapeutic Response Unexpected With Drug Substitution MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis ADReCS
Toxic Skin Eruption MetaADEDB
Upper Respiratory Tract Inflammation MetaADEDB
Urinary Bladder Neoplasms MetaADEDB
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urine Ketone Body Present MetaADEDB
Urine Output Increased MetaADEDB
Urticaria ADReCS
Ventriculo-Peritoneal Shunt MetaADEDB
Viith Nerve Paralysis MetaADEDB
Vision Disorders MetaADEDB
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Wheeze MetaADEDB
Withdrawn SIDER

InAADR: Drug-Protein-ADRs database